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Cited by 308

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The global epidemiology of bladder cancer: a joinpoint regression analysis of its incidence and mortality trends and projection

Open access
Wong, Martin C. S., Fung, Franklin D. H., Leung, Colette, Cheung, Wilson W. L., Goggins, William B., Ng, C. F.·2018·Scientific Reports

Abstract

We tested the hypotheses that the global incidence of bladder cancer was increasing but its mortality was reducing and its incidence was positively correlated with country-specific socioeconomic development. We retrieved data on age-standardized incidence and mortality rates/100,000 from the GLOBOCAN database in 2012. Temporal patterns were examined for 39 countries from the Cancer Incidence in Five Continents volumes I-X and other national registries. We evaluated the correlation between the incidence/mortality rates and Human Development Index (HDI)/ logarithmic values of Gross Domestic Product per capita (GDP). The average annual percent change of the incidence and mortality rates in the most recent 10 years was examined by joinpoint regression analysis. The highest incidence rates were observed in Southern Europe, Western Europe and North America. The mortality rates were the highest in Western Asia and Northern Africa. The incidence was positively correlated with HDI (r = 0.66 [men]; r = 0.50 [women]) and to a lesser extent logarithmic values of GDP per capita (r = 0.60 [men]; r = 0.50 [women], all p < 0.01). Many European countries experienced incidence rise. A substantial mortality reduction was observed in most countries, yet increases in mortality rates were observed in the Philippines and Iceland. These findings identified countries where more preventive actions are required.

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Metadata

Authors
Wong, M. C. S., Fung, F. D. H., Leung, C., Cheung, W. W. L., Goggins, W. B., & Ng, C. F.
Venue
Scientific Reports
Published
2018-01-18
Volume
8
Issue
1
Pages
1129-1129
ISSN
2045-2322 (ISSN-L)
OpenAlex
W2783414919
Cited by
308
References
27
FWCI
10.87
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: The global epidemiology of bladder cancer: a joinpoint regression analysis of its incidence and mortality trends and projection. https://app.cochat.ai/papers/10.1038/s41598-018-19199-z
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Wong, M. C. S., Fung, F. D. H., Leung, C., Cheung, W. W. L., Goggins, W. B., & Ng, C. F. (2018). The global epidemiology of bladder cancer: a joinpoint regression analysis of its incidence and mortality trends and projection. Scientific Reports. https://doi.org/10.1038/s41598-018-19199-z

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