The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
A large-scale population study of early life factors influencing left-handedness
Open accessAbstract
Hand preference is a conspicuous variation in human behaviour, with a worldwide proportion of around 90% of people preferring to use the right hand for many tasks, and 10% the left hand. We used the large cohort of the UK biobank (~500,000 participants) to study possible relations between early life factors and adult hand preference. The probability of being left-handed was affected by the year and location of birth, likely due to cultural effects. In addition, hand preference was affected by birthweight, being part of a multiple birth, season of birth, breastfeeding, and sex, with each effect remaining significant after accounting for all others. Analysis of genome-wide genotype data showed that left-handedness was very weakly heritable, but shared no genetic basis with birthweight. Although on average left-handers and right-handers differed for a number of early life factors, all together these factors had only a minimal predictive value for individual hand preference.
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“Since BOLT-REML heritability estimates and standard errors are close to GCTA-REML estimates (87) this calculator gives an indicative estimate.”
BackgroundBreastfeeding Determinants in Healthy Term Newborns
Colombo, L., Crippa, B., Consonni, D., Bettinelli, M., Agosti, V., Mangino, G., Bezze, E., Mauri, P., Zanotta, L., Roggero, P., et al. (2018) · Nutrients · doi:10.3390/nu10010048 · Cited by 150
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Papadatou-Pastou, M., Ntolka, E., Schmitz, J., Martin, M., Munafò, M. R., Ocklenburg, S., & Paracchini, S. (2020) · Psychological Bulletin · doi:10.1037/bul0000229 · Cited by 526
Brain Lateralization: A Comparative Perspective
Güntürkün, O., Ströckens, F., & Ocklenburg, S. (2020) · Physiological Reviews · doi:10.1152/physrev.00006.2019 · Cited by 484
Atypical Lateralization in Neurodevelopmental and Psychiatric Disorders: What Is the Role of Stress?
Berretz, G., Wolf, O. T., Güntürkün, O., & Ocklenburg, S. (2020) · Cortex · doi:10.1016/j.cortex.2019.12.019 · Cited by 100
Exome-wide analysis implicates rare protein-altering variants in human handedness
Schijven, D., Soheili-Nezhad, S., Fisher, S. E., & Francks, C. (2024) · Nature Communications · doi:10.1038/s41467-024-46277-w · Cited by 27
Self-citation
Metadata
- Authors
- de Kovel, C. G. F., Carrión-Castillo, A., & Francks, C.
- Venue
- Scientific Reports
- Published
- 2019-01-24
- Volume
- 9
- Issue
- 1
- Pages
- 584-584
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W2912157499
- Cited by
- 189
- References
- 5
- FWCI
- 11.90
- Type
- journal article
- Language
- en
- Open access
- gold
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