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Cited by 15Peripheral Nerve DisordersSmoking Behavior and CessationErgonomics and Musculoskeletal Disorders

The DOI matches its Crossref record; 29 of the 29 references it cites were found in a registry or an index.

Smoking is associated with ulnar nerve entrapment: a birth cohort study

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Hulkkonen, Sina, Auvinen, Juha, Miettunen, Jouko, Karppinen, Jaro, Ryhänen, Jorma·2019·Scientific Reports
DOI 10.1038/s41598-019-45675-1PMC PMC6603028
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Abstract

Ulnar nerve entrapment is the second most common compression neuropathy of the upper extremity. It has been associated with smoking in cross-sectional studies. Our aim was to study whether smoking is associated with ulnar nerve entrapment. The study population consisted of the Northern Finland Birth Cohort 1966 participants, who attended the 31-year follow-up in 1997 (N = 8,716). Information on smoking, body mass index (BMI), long-term illnesses, and socio-economic status were recorded at baseline in 1997. Data on hospitalizations due to ulnar nerve entrapment neuropathies was obtained from the Care Register for Health Care, 1997-2016. Hazard ratios (HR) with 95% confidence intervals (CI) and population attributable risk (PAR) were calculated adjusted for gender, BMI and socio-economic status. 66 patients were diagnosed with ulnar nerve entrapment in the follow-up 1997-2016. Before the age of 31 years, smoking ≤10 pack years associated with more than doubled (HR = 2.57, 95% CI = 1.29-5.15) and smoking >10 pack years with more than five-folded (HR = 5.61, 95% CI = 2.80-11.23) risk for ulnar nerve entrapment compared to non-smokers in the adjusted analyses. Adjusted PAR for smoking (reference of no smoking) was 53.6%. In our study, smoking associated with increased risk for ulnar nerve entrapment, accounting for considerable proportion of increased risk.

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  • Psychosocial status, lifestyle, and occupational demands are important risk factors for elbow pain.

    “Psychosocial status [9,10], lifestyle [11,12], and occupational demands (such as heavy load handling and highly repetitive movements with the wrist/hand) [11,13,14,15,16] are important risk factors.”

    From Digital Rehabilitation for Elbow Pain Musculoskeletal Conditions: A Prospective Longitudinal Cohort Study (2022) · cites this paper as [12]

    The Introduction (page unavailable) identifies smoking and occupational biomechanical exposures as risk factors for ulnar nerve entrapment. The Discussion (page unavailable) reports a substantial smoking-associated risk but says socioeconomic status was not significantly associated with entrapment in this study. The paper does not establish these factors as risks for elbow pain generally or substantiate the specified heavy-load and wrist/hand-repetition demands; the citing sentence attaches other references, not this source, to psychosocial status. (LLM, conf=0.84)

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Metadata

Authors
Hulkkonen, S., Auvinen, J., Miettunen, J., Karppinen, J., & Ryhänen, J.
Affiliations
  • University of Helsinki (FI)
  • Oulu University Hospital (FI)
Corresponding author
Hulkkonen, Sina
ORCID
Venue
Scientific Reports
Publisher
Springer Science and Business Media LLC
Published
2019-07-01
Volume
9
Issue
1
Pages
9450-9450
ISSN
2045-2322 (ISSN-L)
DOI
10.1038/s41598-019-45675-1
PMC
PMC6603028
OpenAlex
W2954205385
Cited by
15
References
29
Citations by year
2026: 2 · 2025: 2 · 2024: 2 · 2023: 1 · 2022: 3 · 2021: 2 · 2020: 3
FWCI
1.32
Type
journal article
Language
en
Open access
Licence
Locations
  • Scientific Reports (publishedVersion, cc-by)
  • Europe PMC (PubMed Central) (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • German Medical Science (German Research Foundation) (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion)
  • Työväentutkimus Vuosikirja (submittedVersion)
  • German Medical Science (German Research Foundation) (cc-by)
Topics
  • Health Sciences › Medicine › Clinical Neurology › Peripheral Nerve Disorders
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Smoking Behavior and Cessation
  • Social Sciences › Human Factors and Ergonomics › Ergonomics and Musculoskeletal Disorders
Keywords
ulnar nerve compression, smoking, compression neuropathy, upper extremity neuropathy, pack-years, population attributable risk, Northern Finland Birth Cohort 1966, hospitalization risk
MeSH terms
Adult, Cross-Sectional Studies, Female, Follow-Up Studies, Humans, Male, Registries, Risk Factors, Smoking, Cohort Studies, Body Mass Index, Proportional Hazards Models, Ulnar Nerve Compression Syndromes

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