A plea for caution and guidance about using AI in genomics
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AI systems that design proteins, antibodies, and other therapeutic biomolecules could be used to develop harmful products, such as bioweapons or environmentally disruptive species.
“For example, AI systems that design proteins, antibodies, and other therapeutic biomolecules could be used to develop harmful products, such as bioweapons or environmentally disruptive species [106–108].”
From Autonomous artificial intelligence, scientific research, and human values (2026) · cites this paper as [107]
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Cites
Resurrecting Surviving Neandertal Lineages from Modern Human Genomes
Vernot, B., & Akey, J. M. (2014) · Science · doi:10.1126/science.1245938 · Cited by 562 · see citing works
Artificial intelligence in clinical and genomic diagnostics
Dias, R., & Torkamani, A. (2019) · Genome Medicine · doi:10.1186/s13073-019-0689-8 · Cited by 474 · see citing works
Obtaining genetics insights from deep learning via explainable artificial intelligence
Novakovsky, G., Dexter, N., Libbrecht, M. W., Wasserman, W. W., & Mostafavi, S. (2022) · Nature Reviews Genetics · doi:10.1038/s41576-022-00532-2 · Cited by 387 · see citing works
Resnik, D. B., & Hosseini, M. (2025) · AI and Ethics · doi:10.1007/s43681-024-00493-8 · Cited by 228 · see citing works
Self-citationOrganoids: a systematic review of ethical issues
de Jongh, D., Massey, E. K., Berishvili, E., Fonseca, L. M., Lebreton, F., Bellofatto, K., Bignard, J., Seißler, J., Buerck, L. W.-V., Honarpisheh, M. M., et al. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02950-9 · Cited by 208 · see citing works
Vega, F. M. D. L., Chowdhury, S., Moore, B., Frise, E., McCarthy, J. J., Hernandez, E. J., Wong, T. C., James, K. N., Guidugli, L., Agrawal, P. B., et al. (2021) · Genome Medicine · doi:10.1186/s13073-021-00965-0 · Cited by 173 · see citing works
Neanderthal-like ‘mini-brains’ created in lab with CRISPR
Remmel, A. (2021) · Nature · doi:10.1038/d41586-021-00388-2 · Cited by 4 · see citing works
Flagged first, then by citations
Research works printed but not linked: 3
- [6]Shapiro B Life as We Made it: How 50,000 Years of Human Innovation Refined and Redefined (Basic Books, 2021). 34709892
- [8]Boguslaw D The Intercept https://go.nature.com/4ezOc0y (2022).
- [10]Sensenbrenner FJ House Report 105–239, Human Cloning Research Prohibition Act; https://go.nature.com/4fR9g3Z (1997).
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Autonomous artificial intelligence, scientific research, and human values
Resnik, D. B., Hosseini, M., & Hauswald, R. (2026) · AI and Ethics · doi:10.1007/s43681-025-00908-0 · Cited by 15 · see citing works
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- Authors
- Hosseini, M., & Donohue, C. R.
- Affiliations
- Northwestern University (US)
- National Institutes of Health (US)
- Corresponding author
- Hosseini, Mohammad
- Venue
- Nature Machine Intelligence
- Published
- 2024-11-29
- Volume
- 6
- Issue
- 12
- Pages
- 1409-1410
- ISSN
- 2522-5839 (ISSN-L)
- PMC
- PMC12393819
- OpenAlex
- W4404860008
- Cited by
- 4
- References
- 7
- Citations by year
- 2026: 2 · 2025: 2
- FWCI
- 0.37
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- Nature Machine Intelligence (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Health & Human Services | NIH | National Center for Advancing Translational Sciences (UM1TR005121)
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Social Sciences › Safety Research › Ethics and Social Impacts of AI
- Physical Sciences › Computer Science › Artificial Intelligence › Law, AI, and Intellectual Property
- Keywords
- artificial intelligence in genomics, AI ethics, human cloning, bioethics
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