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Cited by 5Nerve injury and regenerationSpinal Cord Injury ResearchMultiple Sclerosis Research Studies

Spinal cord repair: future directions

Fawcett, J W·1992·Spinal Cord
DOI 10.1038/sc.1992.29
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Abstract

The main cause of disability following spinal injury is failure of axons to regenerate and reconnect the spinal cord with the brain. If patients with cord lesions are ever to make a full recovery some means will have to be found to restore ascending sensory and descending motor connections. Until the last few years there has been a very limited understanding of the reasons why axons in the central nervous system (CNS) fail to regenerate, but as a result of recent work the picture is now much clearer.

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Crossref · 10.1038/sc.1992.29

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10 of 10 references verified0 citation errors · 0 not checkable

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  • The AR signaling pathway elicits its biological effects through both DNA-binding-dependent and non-DNA-binding-dependent pathways, which may be activated by either cytosolically located AR or membrane-localized AR as well as other membrane-localized receptors.

    “The AR signaling pathway elicits its biological effects through both DNA‐binding‐dependent and non‐DNA‐binding‐dependent pathways 32 which may be activated by either cytosolically located AR or membrane localized AR 46 as well as other membrane localized receptors. 35”

    From The role of the androgen receptor in the pathogenesis of obesity and its utility as a target for obesity treatments (2022) · cites this paper as [32]

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Authors
Fawcett, J. W.
Corresponding author
Fawcett, J W
ORCID
Fawcett, J W
Venue
Spinal Cord
Publisher
Springer Science and Business Media LLC
Published
1992-02
Volume
30
Issue
2
Pages
83-85
ISSN
  • 1362-4393 (ISSN-L)
  • 1476-5624
DOI
10.1038/sc.1992.29
OpenAlex
W1974586667
Cited by
5
References
10
Citations by year
2022: 2 · 2021: 1
FWCI
0.14
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)
Locations
  • Spinal Cord (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Spinal Cord Injury Research
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
Keywords
spinal cord injury, axon regeneration, central nervous system regeneration, spinal cord repair, functional recovery, descending motor pathways, ascending sensory pathways
MeSH terms
Humans, Nerve Regeneration, Spinal Cord Injuries

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