Cited by 20Atrial Fibrillation Management and OutcomesCardiac pacing and defibrillation studiesCardiac Arrhythmias and Treatments

Overview of management of atrial fibrillation in symptomatic elderly patients: pharmacologic therapy versus AV node ablation

Bradley, D J, Shen, W-K·2007·Clinical Pharmacology & Therapeutics

Abstract

Atrial fibrillation is an abnormal heart rhythm affecting the upper chambers of the heart in which uncoordinated electrical depolarizations lead to ineffective contractions. Approximately five million patients in the US have atrial fibrillation, and this number is expected to double to 10 million over the next 30 years. Advancing age is a major risk factor for the development of atrial fibrillation; new cases of atrial fibrillation are diagnosed in men over age 80 at the rate of 2% per year. Although several drugs are available for management of atrial fibrillation, the efficacy of these drugs may be limited in elderly patients. In this review, we provide an overview of management of atrial fibrillation, with special emphasis on pharmacologic therapy versus arteriovenous (AV) node ablation in symptomatic elderly patients.

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Crossref · 10.1038/sj.clpt.6100062

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20 of 20 references verified0 citation errors · 0 not checkable

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Authors
Bradley, D. J., & Shen, W.-K.
Affiliations
Mayo Clinic (US)
Corresponding author
Shen, W-K
Venue
Clinical Pharmacology & Therapeutics
Publisher
Wiley
Published
2007-02
Volume
81
Issue
2
Pages
284-287
ISSN
  • 0009-9236 (ISSN-L)
  • 1532-6535
OpenAlex
W2062685615
Cited by
20
References
20
Citations by year
2024: 3 · 2022: 1 · 2021: 5 · 2020: 1 · 2018: 1 · 2016: 3 · 2012: 1
FWCI
0.70
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Pharmacology & Therapeutics (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Atrial Fibrillation Management and Outcomes
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords
atrial fibrillation, elderly patients, pharmacotherapy, AV node ablation, antiarrhythmic drugs, symptomatic atrial fibrillation, atrial fibrillation incidence
MeSH terms
Age Factors, Aged, Aged, 80 and over, Atrial Fibrillation, Atrioventricular Node, Humans, Practice Patterns, Physicians', Practice Guidelines as Topic

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