Matrix Metalloproteinase-Mediated Disruption of Tight Junction Proteins in Cerebral Vessels is Reversed by Synthetic Matrix Metalloproteinase Inhibitor in Focal Ischemia in Rat

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Seizures Are Associated with Blood-Brain Barrier Disruption in a Piglet Model of Neonatal Hypoxic-Ischaemic Encephalopathy

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A differential release of matrix metalloproteinases 9 and 2 during coronary artery bypass grafting and off-pump coronary artery bypass surgery

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Multimodal Nanoprobes Evaluating Physiological Pore Size of Brain Vasculatures in Ischemic Stroke Models

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Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice

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SPARC Aggravates Blood‐Brain Barrier Disruption via Integrin αVβ3/MAPKs/MMP‐9 Signaling Pathway after Subarachnoid Hemorrhage

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The ATX–LPA Axis Regulates Vascular Permeability during Cerebral Ischemic-Reperfusion

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Therapeutic efficacy of matrix metalloproteinase-12 suppression on neurological recovery after ischemic stroke: Optimal treatment timing and duration

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Serum Proteins Associated with Blood–Brain Barrier as Potential Biomarkers for Seizure Prediction

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Embryonic 6:2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood-testis barrier in offspring mice

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The Role of Gut Microbiota in Blood–Brain Barrier Disruption after Stroke

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Marine pharmacology: therapeutic targeting of matrix metalloproteinases in neuroinflammation

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Apocynum venetum Leaf Extract Attenuates Disruption of the Blood–Brain Barrier and Upregulation of Matrix Metalloproteinase-9/-2 in a Rat Model of Cerebral Ischemia–Reperfusion Injury

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Treatment with sodium orthovanadate reduces blood–brain barrier disruption via phosphatase and tensin homolog deleted on chromosome 10 (PTEN) phosphorylation in experimental subarachnoid hemorrhage

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Claudin-5 protein is a new differential marker for histopathological differential diagnosis of canine hemangiosarcoma.

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Neuroinflammation and Alteration of the Blood-Brain Barrier in Alzheimer´s Disease

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Chloride Intracellular Channel Proteins (CLICs) and Malignant Tumor Progression: A Focus on the Preventive Role of CLIC2 in Invasion and Metastasis

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Inhibition of MMP-9 attenuates hypertensive cerebrovascular dysfunction in Dahl salt-sensitive rats

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The Disruption of the Endothelial Barrier Contributes to Acute Lung Injury Induced by Coxsackievirus A2 Infection in Mice

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Propofol protects against blood-spinal cord barrier disruption induced by ischemia/reperfusion injury

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Need for a Paradigm Shift in the Treatment of Ischemic Stroke: The Blood-Brain Barrier

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An Emerging Role of Degrading Proteinases in Hypertension and the Metabolic Syndrome: Autodigestion and Receptor Cleavage

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Effects of Nigella sativa Extract on Markers of Cerebral Angiogenesis after Global Ischemia of Brain in Rats

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FGFR1 participates in damage to the blood-brain barrier after intra-abdominal hypertension and traumatic brain injury of rats via ERK pathway

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Regulation of pathological blood-brain barrier for intracranial enhanced drug delivery and anti-glioblastoma therapeutics

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Matrix metalloproteinase inhibition counteracts impairment of cortical experience‐dependent plasticity after photothrombotic stroke

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Regulation of Proteases after Spinal Cord Injury

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Platonin preserves blood–brain barrier integrity in septic rats

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Upregulation of tissue inhibitor of metalloproteinase-1 contributes to restoration of the extracellular matrix in the rabbit basilar artery during cerebral vasospasm after subarachnoid hemorrhage

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Activation of MMP-9 by human lung epithelial cells in response to the cystic fibrosis-associated pathogen Burkholderia cenocepacia reduced wound healing in vitro

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Regulation of Blood–Brain Barrier Permeability via JNK Signaling Pathway: Mechanisms and Potential Therapeutic Strategies for Ischemic Stroke, Alzheimer’s Disease and Brain Tumors

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Protein kinase C and endothelial dysfunction in select vascular diseases

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Cardiovascular disease and depression: a bidirectional relationship and its clinical implications

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Matrix Metalloproteinase 9 and Vasodilator-Stimulated Phosphoprotein Related to Acute Kidney Injury in Severe Acute Pancreatitis Rats

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Natural Products in the Prevention of Metabolic Diseases: Lessons Learned from the 20th KAST Frontier Scientists Workshop

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Pericytes of Indirect Contact Coculture Decrease Integrity of Inner Blood-Retina Barrier Model In Vitro by Upgrading MMP-2/9 Activity

Yang, T., Guo, L., Fang, Y., Liang, M., Zheng, Y., Pan, M., Meng, C., & Liu, G. (2021) · Disease Markers · doi:10.1155/2021/7124835 · Cited by 12

Cerebral microvascular matrix metalloproteinase-3 (MMP3) contributes to vascular injury after stroke in female diabetic rats

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Impact of Moderate Blast Exposures on Thrombin Biomarkers Assessed by Calibrated Automated Thrombography in Rats

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Quorum‐sensing molecule dihydroxy‐2,3‐pentanedione and its analogs as regulators of epithelial integrity

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The autodigestion hypothesis and receptor cleavage in diabetes and hypertension

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Blood–brain barrier disruption in dementia: Nano‐solutions as new treatment options

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Protective effects of butyrate on cerebral ischaemic injury in animal models: a systematic review and meta-analysis

Yan, S., Ji, Q., Ding, J., Liu, Z., Wei, W., Li, H., Li, L., Ma, C., Liao, D., He, Z., et al. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1304906 · Cited by 12

Therapeutic Potential of Natural Compounds for Brain Ischemia-Reperfusion Injury

Yoo, K., Won, M., Ahn, J. H., & Park, J. H. (2025) · Biology · doi:10.3390/biology14091153 · Cited by 11

Mechanism of blood-retinal barrier breakdown induced by HIV-1 (Review)

Che, X., Fan, X., & Wang, Z. (2014) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2014.1521 · Cited by 11

DIDS Prevents Ischemic Membrane Degradation in Cultured Hippocampal Neurons by Inhibiting Matrix Metalloproteinase Release

Pamenter, M. E., Ryu, J., Hua, S. T., Perkins, G. A., Mendiola, V. L., Gu, X. Q., Ellisman, M. H., & Haddad, G. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0043995 · Cited by 11

Transcriptional Response and Morphological Features of the Neurovascular Unit and Associated Extracellular Matrix After Experimental Stroke in Mice

Aleithe, S., Blietz, A., Mages, B., Hobusch, C., Härtig, W., & Michalski, D. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-1604-4 · Cited by 11

Attachment of Cancer Urothelial Cells to the Bladder Epithelium Occurs on Uroplakin-Negative Cells and Is Mediated by Desmosomal and Not by Classical Cadherins

Jerman, U. D., Višnjar, T., Hafner‐Bratkovič, I., Resnik, N., Pavlin, M., Veranič, P., & Kreft, M. E. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22115565 · Cited by 11

Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier

Tirumuru, N., Pretto, C. D., de Castro-Jorge, L. A., & Spindler, K. R. (2016) · mSphere · doi:10.1128/msphere.00079-16 · Cited by 11

Effects of electromagnetic pulse exposure on gelatinase of blood–brain barrierin vitro

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Ghrelin ameliorates blood–brain barrier disruption during systemic hypoxia

Mohaddes, G., Abdolalizadeh, J., Babri, S., & Hossienzadeh, F. (2017) · Experimental Physiology · doi:10.1113/ep086068 · Cited by 10

Assessment of recombinant tissue plasminogen activator (rtPA) toxicity in cultured neural cells and subsequent treatment with poly-arginine peptide R18D

Kenna, J. E., Anderton, R. S., Knuckey, N. W., & Meloni, B. P. (2020) · Neurochemical Research · doi:10.1007/s11064-020-03004-3 · Cited by 11

The role of nuclear factor kappa B (NF-κB) in filarial pathology

Fordjour, F. A., Asiedu, E., Larbi, A. A., & Kwarteng, A. (2021) · Journal of Cell Communication and Signaling · doi:10.1007/s12079-021-00607-5 · Cited by 11

CLINICAL PATHOPHYSIOLOGY OF CEREBRAL EDEMA (PART 2)

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Pharmacologic management of brain edema

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Multiple sclerosis: etiology in the context of neurovascular unit and immune system involvement and advancements with in vitro blood–brain barrier models

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The Relationship Between Cerebral Reperfusion And Regional Expression Of Matrix Metalloproteinase-9 In Rat Brain Following Focal Cerebral Ischemia

Douglas, A., Shearer, J. A., Okolo, A., Pandit, A. S., Gilvarry, M., & Doyle, K. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.10.034 · Cited by 10

Role of albumin on endothelial basement membrane and hemostasis in a rat model of hemorrhagic shock

Torres, L. N., Salgado, C. L., Dubick, M. A., Cap, A. P., & Filho, I. P. T. (2021) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0000000000003298 · Cited by 10

The protective effects of butorphanol tartrate against homocysteine-induced blood-brain barrier dysfunction

Shen, S., Wang, J., Zhao, Q., & Hu, Q. (2022) · Bioengineered · doi:10.1080/21655979.2022.2037953 · Cited by 10

Neurobiochemical characteristics of arginine-rich peptides explain their potential therapeutic efficacy in neurodegenerative diseases

Eskandari, S., Rezayof, A., Asghari, S. M., & Hashemizadeh, S. (2023) · Neuropeptides · doi:10.1016/j.npep.2023.102356 · Cited by 10

Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia

Rosenberg, G. A., & Yang, Y. R. (2007) · Neurosurgical FOCUS · doi:10.3171/foc.2007.22.5.5 · Cited by 358

Relationship of gelatinases-tight junction proteins and blood-brain barrier permeability in the early stage of cerebral ischemia and reperfusion.

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Matrix Metalloproteinases and TIMPs Are Associated With Blood-Brain Barrier Opening After Reperfusion in Rat Brain

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Early Inhibition of MMP Activity in Ischemic Rat Brain Promotes Expression of Tight Junction Proteins and Angiogenesis During Recovery

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Early appearance of activated matrix metalloproteinase-9 and blood–brain barrier disruption in mice after focal cerebral ischemia and reperfusion

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