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The effect of the fast of Ramadan on ambulatory blood pressure in treated hypertensives
Abstract
Every year, millions of Moslems throughout the world fast from sunrise till sunset daily during the month of Ramadan, that is, experience repeated cycles of fasting-refeeding. Studies in animal models have shown that repeated cycles of fasting-refeeding may cause or exacerbate hypertension. Changes in sleeping patterns as well as changes in medication timing may also influence ambulatory blood pressure. We undertook this study in order to examine the effect of the Ramadan fast on treated hypertensive subjects. Seventeen hypertensive subjects were examined, and 24-h blood pressure monitoring was carried out twice, before and during the last week of the Ramadan. All continued their medications, which were all once-daily preparations. Twenty-four hour mean blood pressure as well as average awake and average asleep blood pressure were compared. There was no difference between mean blood pressure before and during the Ramadan (138.5 +/- 18.5/77.2 +/- 8.1 mm Hg vs 136.4 +/- 20.4/75.7 +/- 5.9 mm Hg, P-nonsignificant). Blood pressure load also did not differ before and during Ramadan (systolic load 49% vs. 44%, diastolic load 21% vs. 18%, P-nonsignificant). Weight was reduced by 1.4 +/- 1.6 kg (P < 0.002). We conclude, that according to our findings, treated, hypertensive patients may be assured that, with continuation of previous medications, traditional fasting during the month of Ramadan can be safely undertaken.
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Among the 25 highest-quality weight studies, 11 (44%) reported greater weight among the more R/S and five (20%) found lower weight or less underweight.
“Among the 25 studies with the highest quality ratings, 11 (44%) reported greater weight among the more R/S [82, 317–322] and five (20%) found lower weight (or less underweight [323]).”
From Religion, Spirituality, and Health: The Research and Clinical Implications (2012) · cites this paper as [323]
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Metadata
- Authors
- Perk, G., Ghanem, J., Aamar, S., Ben-Ishay, D., & Bursztyn, M.
- Affiliations
- Hadassah Medical Center (IL)
- Corresponding author
- Bursztyn, M
- ORCID
- Venue
- Journal of Human Hypertension
- Published
- 2001-10-01
- Volume
- 15
- Issue
- 10
- Pages
- 723-725
- ISSN
- 0950-9240 (ISSN-L)
- 1476-5527
- OpenAlex
- W1974107754
- Cited by
- 134
- References
- 15
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 44 · 2022: 4 · 2021: 7 · 2020: 10 · 2019: 4 · 2018: 1 · 2017: 9 · 2016: 7 · 2015: 4 · 2014: 9 · 2013: 4 · 2012: 4
- FWCI
- 1.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Human Hypertension (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Dietary Effects on Health
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Syncope and Autonomic Disorders
- Keywords
- Ramadan fasting, hypertension, antihypertensive drugs, ambulatory blood pressure, 24-hour ambulatory blood pressure monitoring, blood pressure load, weight loss, timing of drug administration, sleep blood pressure
- MeSH terms
- Angiotensin-Converting Enzyme Inhibitors, Antihypertensive Agents, Atenolol, Blood Pressure, Calcium Channel Blockers, Fasting, Female, Humans, Hydrochlorothiazide, Hypertension, Islam, Male, Middle Aged, Nifedipine, Religion and Medicine, Sleep, Verapamil, Blood Pressure Monitoring, Ambulatory
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