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Cited by 397Dialysis and Renal Disease ManagementCardiac electrophysiology and arrhythmiasPotassium and Related Disorders

The DOI matches its Crossref record; 31 of the 34 references it cites were found in a registry or an index.

Characteristics of sudden death in hemodialysis patients

Open access
Bleyer, A.J., Hartman, J., Brannon, P.C., Reeves-Daniel, A., Satko, S.G., Russell, G.·2006·Kidney International
DOI 10.1038/sj.ki.5000446
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Abstract

Hemodialysis (HD) is an intermittent procedure during which large fluid and electrolyte shifts occur. We hypothesized that sudden death occurrences in HD patients are related to the timing of HD, and that they occur more frequently in the 12 h period starting with dialysis and in the 12 h period at the end of the dialysis-free weekend interval. In a retrospective study, 228 patient deaths were screened to determine if they met the criteria for sudden death. Information was obtained from clinic charts, dialysis center records, and interview of witnesses of the death event. There were 80 HD patients who met the criteria for sudden death. A bimodal distribution of death occurrences was present, with a 1.7-fold increased death risk occurring in the 12 h period starting with the dialysis procedure and a threefold increased risk of death in the 12 h before HD at the end of the weekend interval (P=0.011). Patients with sudden death had a high prevalence of congestive heart failure and coronary artery disease. Only 40% of patients experiencing sudden death were receiving beta-blockers, and the prior monthly serum potassium value was less than 4 mEq/l in 25%. Sudden death is temporally related to the HD procedure. Every other day HD could be beneficial in preventing sudden death. Careful attention to the usage of beta-blockers and to the maintenance of normal serum potassium values is indicated in HD patients at risk for sudden death.

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Research works printed but not linked: 4

  1. Ifudu, 2004, Dietary potassium is not the sole determinant of serum potassium concentration in hemodialysis patients, Dial Transplant, 33, 684
  2. Arrizabalaga, 1983, Increase in serum potassium caused by beta-2 adrenergic blockage in terminal renal failure: absence of mediation by insulin or aldosterone, Proc Eur Dial Transplant Assoc, 20, 572
  3. Bleyer, 1999, Sudden and cardiac death rates in hemodialysis patients, Kidney Int, 55, 1553, 10.1046/j.1523-1755.1999.00391.x · DOI
  4. Popovtzer, 2004, Disorders of calcium, phosphorus, vitamin D, and parathyroid hormone activity, chapter 6, 241

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Metadata

Authors
Bleyer, A. J., Hartman, J., Brannon, P. C., Reeves-Daniel, A., Satko, S. G., & Russell, G.
Affiliations
Wake Forest University Health Sciences (US)
Corresponding author
Bleyer, A.J.
ORCID
Venue
Kidney International
Publisher
Elsevier BV
Published
2006-06
Volume
69
Issue
12
Pages
2268-2273
ISSN
0085-2538 (ISSN-L)
DOI
10.1038/sj.ki.5000446
OpenAlex
W2027678078
Cited by
397
References
34
Citations by year
2026: 10 · 2025: 22 · 2024: 9 · 2023: 16 · 2022: 16 · 2021: 23 · 2020: 21 · 2019: 21 · 2018: 20 · 2017: 34 · 2016: 12 · 2015: 21 · 2014: 19 · 2013: 22 · 2012: 32
FWCI
10.74
Type
journal article
Language
en
Open access
Licence
Locations
  • Kidney International (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Nephrology › Dialysis and Renal Disease Management
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
  • Health Sciences › Medicine › Nephrology › Potassium and Related Disorders
Keywords
sudden death, hemodialysis, timing of dialysis, beta-blockers, serum potassium, congestive heart failure, coronary artery disease, mortality risk factors
MeSH terms
Adrenergic beta-Antagonists, Aged, Coronary Artery Disease, Death, Sudden, Female, Heart Failure, Renal Dialysis, Humans, Hypokalemia, Male, Mass Screening, Middle Aged, Potassium, Retrospective Studies, Risk Factors, Time Factors, Prevalence

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