Cited by 39Tryptophan and brain disordersStress Responses and CortisolTreatment of Major Depression

Cytokines, p38 MAP kinase and the pathophysiology of depression

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Miller, Andrew H, Raison, Charles L·2006·Neuropsychopharmacology

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Crossref · 10.1038/sj.npp.1301032

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  • Elevated plasma proinflammatory cytokine levels have been observed in diagnosed MDD patients who attempted suicide, had suicidal ideation, or had geriatric depression, suggesting a positive association between inflammatory mechanisms and different depressive disorder subsets.

    “studies have also shown elevated plasma levels of proinflammatory cytokines in diagnosed MDD patients who had attempted suicide, with suicidal ideation, and geriatric depression suggesting that inflammatory mechanisms may be positively associated with different subsets of depressive disorders (Miller et al., 2006;O'Donavan et al., 2013;Sublette et al., 2011).”

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Authors
Miller, A. H., & Raison, C. L.
Affiliations
Emory University (US)
Corresponding author
Miller, Andrew H
Venue
Neuropsychopharmacology
Published
2006-09-18
Volume
31
Issue
10
Pages
2089-2090
ISSN
  • 0893-133X (ISSN-L)
  • 1740-634X
OpenAlex
W2068474941
Cited by
39
References
7
Citations by year
2025: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 2 · 2016: 3 · 2014: 5 · 2013: 2 · 2012: 1
Type
journal article
Language
en
Open access
Locations
  • Neuropsychopharmacology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Biological Psychiatry › Tryptophan and brain disorders
  • Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
Keywords
depression, inflammatory cytokines, p38 MAPK, innate immunity, neuroinflammation, stress-induced inflammation, sympathetic nervous system, chemokines, acute phase proteins, adhesion molecules
MeSH terms
Depression, Humans, Cytokines, p38 Mitogen-Activated Protein Kinases

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