Environmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in mice

Pan-Montojo, Francisco, Schwarz, Mathias, Winkler, Clemens, Arnhold, Mike, O'Sullivan, Gregory A., Pal, Arun, Said, Jonas, Marsico, Giovanni +5 more·2012·Scientific Reports

Cited by (403)

Items 101–200 of 403

  1. Research on the Premotor Symptoms of Parkinson’s Disease: Clinical and Etiological Implications
    Chen, Honglei, Burton, Edward A., Ross, G. Webster, Huang, Xuemei, Savica, Rodolfo, Abbott, Robert D., Ascherio, Alberto, Caviness, John N., Gao, Xiang, Gray, Kimberly A. et al. · 2013 · Environmental Health Perspectives
  2. The gut-brain axis and Parkinson disease: Clinical and pathogenetic relevance
    Menozzi, Elisa, Macnaughtan, Jane, Schapira, Anthony H. V. · 2021 · Annals of Medicine
  3. Microbiome, Parkinson’s Disease and Molecular Mimicry
    Fabiana Miraglia, Emanuela Colla · 2019 · Cells
  4. Gut microenvironmental changes as a potential trigger in Parkinson’s disease through the gut–brain axis
    Szu‐Ju Chen, Chin‐Hsien Lin · 2022 · Journal of Biomedical Science
  5. The Contribution of α -Synuclein Spreading to Parkinson’s Disease Synaptopathy
    Francesca Longhena, Gaia Faustini, Cristina Missale, Marina Pizzi, PierFranco Spano, Arianna Bellucci · 2017 · Neural Plasticity
  6. Animal models of brain-first and body-first Parkinson's disease
    Nathalie Van Den Berge, Ayşe Ulusoy · 2021 · Neurobiology of Disease
  7. Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation
    Dharmin Rokad, Shivani Ghaisas, Dilshan S. Harischandra, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy · 2016 · Brain Research Bulletin
  8. Spreading of α-synuclein in the face of axonal transport deficits in Parkinson's disease: A speculative synthesis
    Jennifer T. Lamberts, Erin N. Hildebrandt, Patrik Brundin · 2014 · Neurobiology of Disease
  9. Premotor Diagnosis of Parkinson’s Disease
    Heinz Reichmann · 2017 · Neuroscience Bulletin
  10. Distribution of α-synuclein in the spinal cord and dorsal root ganglia in an autopsy cohort of elderly persons
    Hiroyuki Sumikura, Masaki Takao, Hiroyuki Hatsuta, Shinji Ito, Yuta Nakano, Akiko Uchino, Akane Nogami, Yuko Saito, Hideki Mochizuki, Shigeo Murayama · 2015 · Acta Neuropathologica Communications
  11. THE INTESTINAL MICROBIOME IN HUMAN HEALTH AND DISEASE.
    Herbert L. DuPont, Zhi‐Dong Jiang, Andrew W. Dupont, Netanya Sandler Utay · 2020 · PubMed Central
  12. Extracellular Vesicles in Alzheimer’s and Parkinson’s Disease: Small Entities with Large Consequences
    Charysse Vandendriessche, Arnout Bruggeman, Caroline Van Cauwenberghe, Roosmarijn E. Vandenbroucke · 2020 · Cells
  13. C/EBPβ/AEP is age-dependently activated in Parkinson’s disease and mediates α-synuclein in the gut and brain
    Wang, Hualong, Chen, Guiqin, Ahn, Eun Hee, Xia, Yiyuan, Kang, Seong Su, Liu, Xia, Liu, Chang, Han, Ming-Hu, Chen, Shengdi, Ye, Keqiang · 2023 · npj Parkinson's Disease
  14. Roles of α‑synuclein in gastrointestinal microbiome dysbiosis‑related Parkinson's disease progression (Review)
    Qingchun Lei, Tingting Wu, Jin Wu, Xiaogang Hu, Yingxia Guan, Ying Wang, Jinyuan Yan, Guolin Shi · 2021 · Molecular Medicine Reports
  15. Involvement of the immune system, endocytosis and EIF2 signaling in both genetically determined and sporadic forms of Parkinson's disease
    Eugénie Mutez, Aurore Nkiliza, Karim Bélarbi, Amélie de Broucker, Christel Vanbesien-Mailliot, Séverine Bleuse, Aurélie Duflot, Thomas Comptdaer, Pierre Semaille, Renaud Blervaque et al. · 2013 · Neurobiology of Disease
  16. Subcellular expression and neuroprotective effects of SK channels in human dopaminergic neurons
    Amalia M. Dolga, A de Andrade, Lilja Meissner, H-G. Knaus, Matthias Höllerhage, Palle Christophersen, Hans Zischka, Nikolaus Plesnila, Günter U. Höglinger, Carsten Culmsee · 2014 · Cell Death and Disease
  17. The pathomechanisms underlying Parkinson's disease
    K. A. Jellinger · 2014 · Expert Review of Neurotherapeutics
  18. Vagotomy and insights into the microbiota-gut-brain axis
    Yunpeng Liu, Paul Forsythe · 2021 · Neuroscience Research
  19. Therapeutic properties of green tea against environmental insults
    Lixia Chen, Huanbiao Mo, Ling Zhao, Weimin Gao, Shu Fen Wang, Meghan M. Cromie, Chuanwen Lu, Jia‐Sheng Wang, Chwan‐Li Shen · 2016 · The Journal of Nutritional Biochemistry
  20. Exosomes in Toxicology: Relevance to Chemical Exposure and Pathogenesis of Environmentally Linked Diseases
    Dilshan S. Harischandra, Shivani Ghaisas, Dharmin Rokad, Anumantha G. Kanthasamy · 2017 · Toxicological Sciences
  21. The gut in Parkinson’s disease: Bottom‐up, top‐down, or neither?
    Laurène Leclair‐Visonneau, Michel Neunlist, Pascal Derkinderen, Thibaud Lebouvier · 2019 · Neurogastroenterology & Motility
  22. Review: Spreading the word: precise animal models and validated methods are vital when evaluating prion‐like behaviour of alpha‐synuclein
    Nolwen L. Rey, Sonia George, Patrik Brundin · 2015 · Neuropathology and Applied Neurobiology
  23. The importance of preclinical diagnostics in Parkinson disease
    Sneha Mantri, James F. Morley, Andrew D. Siderowf · 2018 · Parkinsonism & Related Disorders
  24. Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition
    Rebecca Zhangqiuzi Fan, Min Amy Guo, Shouqing Luo, Mei Cui, Kim Tieu · 2019 · Acta Neuropathologica Communications
  25. Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy
    Allison J. Schaser, Teresa L. Stackhouse, Leah J. Weston, Patrick C. Kerstein, Valerie R. Osterberg, Claudia S. López, Dennis W. Dickson, Kelvin C. Luk, Charles K. Meshul, Randall L. Woltjer et al. · 2020 · Acta Neuropathologica Communications
  26. Gut mucosal cells transfer α-synuclein to the vagus nerve
    Rashmi Chandra, Arpine Sokratian, Katherine Ramos Chavez, Stephanie King, Sandip Madhusudan Swain, Joshua C. Snyder, Andrew B. West, Rodger A. Liddle · 2023 · JCI Insight
  27. Footprints of a microbial toxin from the gut microbiome to mesencephalic mitochondria
    A. Raquel Esteves, Mario Muñoz, Daniela Nunes‐Costa, Emanuel Candeias, Diana Filipa Silva, João Duarte Magalhães, A. Raquel Pereira-Santos, Ildete L. Ferreira, Susana Alarico, Igor Tiago et al. · 2021 · Gut
  28. The Skin and Parkinson's Disease: Review of Clinical, Diagnostic, and Therapeutic Issues
    Matěj Škorvánek, Kailash P. Bhatia · 2016 · Movement Disorders Clinical Practice
  29. Are We What We Eat? Impact of Diet on the Gut–Brain Axis in Parkinson’s Disease
    Margherita Alfonsetti, Vanessa Castelli, Michele d’Angelo · 2022 · Nutrients
  30. Products of the Parkinson's disease-related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival
    Yusuke Toyoda, Cihan Erkut, Francisco J. Pan-Montojo, Sebastian Boland, Martin P. Stewart, Daniel J. Müller, Wolfgang Wurst, Anthony A. Hyman, Teymuras V. Kurzchalia · 2014 · Biology Open
  31. G ut F eelings Ab out α‐ S ynuclein in G astrointestinal B iopsies: B iomarker in the M aking?
    Claudio Ruffmann, Laura Parkkinen · 2016 · Movement Disorders
  32. Environmental Exposures and Extracellular Vesicles: Indicators of Systemic Effects and Human Disease
    Christina M. Eckhardt, Andrea Baccarelli, Haotian Wu · 2022 · Current Environmental Health Reports
  33. Environmental pollutants and exosomes: A new paradigm in environmental health and disease
    Afsaneh Javdani-Mallak, Iman Salahshoori · 2024 · The Science of The Total Environment
  34. Prevention of the degeneration of human dopaminergic neurons in an astrocyte co‐culture system allowing endogenous drug metabolism
    Liudmila V. Efremova, Stefan Schildknecht, Martina Adam, Regina Pape, Simon Gutbier, Benjamin Hanf, Alexander Bürkle, Marcel Leist · 2015 · British Journal of Pharmacology
  35. Editor’s Highlight: Nlrp3 Is Required for Inflammatory Changes and Nigral Cell Loss Resulting From Chronic Intragastric Rotenone Exposure in Mice
    Eileen M. Martinez, Alison L. Young, Yash R. Patankar, Brent L. Berwin, Li Wang, Katharine M. von Herrmann, Jaclyn M. Weier, Matthew C. Havrda · 2017 · Toxicological Sciences
  36. Specific Pesticide-Dependent Increases in α-Synuclein Levels in Human Neuroblastoma (SH-SY5Y) and Melanoma (SK-MEL-2) Cell Lines
    Areski Chorfa, Dominique Bétemps, Eric Morignat, Corinne Lazizzera, Kevin N. Hogeveen, Thibault Andrieu, Thierry Baron · 2013 · Toxicological Sciences
  37. Erythrocytic α-synuclein contained in microvesicles regulates astrocytic glutamate homeostasis: a new perspective on Parkinson’s disease pathogenesis
    Lifu Sheng, Tessandra Stewart, Dishun Yang, Eric Thorland, David Soltys, Patrick Aro, Tarek Khrisat, Zhiying Xie, Na Li, Zongran Liu et al. · 2020 · Acta Neuropathologica Communications
  38. Enteric Glia at the Crossroads between Intestinal Immune System and Epithelial Barrier: Implications for Parkinson Disease
    Laura Benvenuti, Vanessa D’Antongiovanni, Carolina Pellegrini, Luca Antonioli, Nunzia Bernardini, Corrado Blandizzi, Matteo Fornai · 2020 · International Journal of Molecular Sciences
  39. Environmental neurotoxicant-induced dopaminergic neurodegeneration: a potential link to impaired neuroinflammatory mechanisms
    Arthi Kanthasamy, Huajun Jin, Adhithiya Charli, Vellareddy Anantharam, Anumantha G. Kanthasamy · 2019 · Pharmacology & Therapeutics
  40. Parkinson's Disease: Risk Factor Modification and Prevention
    Suraj M. Rajan, Bonnie M. Kaas · 2022 · Seminars in Neurology
  41. Exploiting the therapeutic potential of ready-to-use drugs: Repurposing antibiotics against amyloid aggregation in neurodegenerative diseases
    Sergio B. Socías, Florencia González‐Lizárraga, César L. Ávila, Cecilia Vera, Leonardo Acuña, Julia Elisa Sepulveda-Diaz, Elaine Aparecida Del Bel, Rita Raisman‐Vozari, Rosana Nieves Chehín · 2017 · Progress in Neurobiology
  42. The Gut and Nonmotor Symptoms in Parkinson's Disease
    Lisa Klingelhoefer, Heinz Reichmann · 2017 · International review of neurobiology
  43. Oral Exposure to Paraquat Triggers Earlier Expression of Phosphorylated α-Synuclein in the Enteric Nervous System of A53T Mutant Human α-Synuclein Transgenic Mice
    Nicolas Naudet, Emilie Antier, Damien Gaillard, Eric Morignat, Latifa Lakhdar, Thierry Baron, Anna A. Bencsik · 2017 · Journal of Neuropathology & Experimental Neurology
  44. Microbes Tickling Your Tummy: the Importance of the Gut-Brain Axis in Parkinson’s Disease
    Paula Perez‐Pardo, Mitch Hartog, Johan Garssen, Aletta D. Kraneveld · 2017 · Current Behavioral Neuroscience Reports
  45. Peptidoglycan recognition protein genes and risk of Parkinson's disease
    Samuel M. Goldman, Freya Kamel, George Webster Ross, Sarah A. Jewell, Connie Marras, Jane A. Hoppin, David M. Umbach, Grace S. Bhudhikanok, Cheryl Meng, Monica Korell et al. · 2014 · Movement Disorders
  46. Excessive levels of nitric oxide in rat model of Parkinson’s disease induced by rotenone
    Zhong-kui Xiong, Juan Lang, Gang Xu, HAI-YU LI, Yun Zhang, Lei Wang, YAO SU, AI-JING SUN · 2014 · Experimental and Therapeutic Medicine
  47. The nonmotor features of Parkinson's disease: pathophysiology and management advances
    Heinz Reichmann, Moritz Brandt, Lisa Klingelhoefer · 2016 · Current Opinion in Neurology
  48. Gastrointestinal disorders in Parkinson’s disease and other Lewy body diseases
    Masaaki Hirayama, Hiroshi Nishiwaki, Tomonari Hamaguchi, Kinji Ohno · 2023 · npj Parkinson s Disease
  49. Isolation of high-purity myenteric plexus from adult human and mouse gastrointestinal tract
    David Grundmann, Markus Klotz, Holger Rabe, Matthias Glanemann, Karl‐Herbert Schäfer · 2015 · Scientific Reports
  50. Considerations on the role of environmental toxins in idiopathic Parkinson’s disease pathophysiology
    Francisco J. Pan-Montojo, Heinz Reichmann · 2014 · Translational Neurodegeneration
  51. Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia†
    EFSA Panel on Plant Protection Products and their residues (PPR), Colin Ockleford, Paulien Adriaanse, Philippe J. Berny, T.C.M. Brock, Sabine Duquesne, Sandro Grilli, Antonio F. Hernández, Susanne Hougaard Bennekou, Michael Klein et al. · 2017 · EFSA Journal
  52. α-Synuclein Pathology in Synucleinopathies: Mechanisms, Biomarkers, and Therapeutic Challenges
    Óscar Arias-Carrión, Magdalena Guerra‐Crespo, Francisco Javier Padilla-Godínez, Luis Oskar Soto-Rojas, Elı́as Manjarrez · 2025 · International Journal of Molecular Sciences
  53. Beyond the Microbiota: Understanding the Role of the Enteric Nervous System in Parkinson’s Disease from Mice to Human
    Martina Montanari, Paola Imbriani, Paola Bonsi, Giuseppina Martella, Antonella Peppe · 2023 · Biomedicines
  54. The Body, the Brain, the Environment, and Parkinson’s Disease
    Earl Ray Dorsey, Briana R. De Miranda, Jacob Horsager, Per Borghammer · 2024 · Journal of Parkinson s Disease
  55. Distinct subcellular localization of the neuronal marker HuC/D reveals hypoxia‐induced damage in enteric neurons
    An-Sofie Desmet, Carla Cirillo, Pieter Vanden Berghe · 2014 · Neurogastroenterology & Motility
  56. Alpha-synuclein and iron: two keys unlocking Parkinson’s disease
    Paul Lingor, Eleonora Carboni, Jan Christoph Koch · 2017 · Journal of Neural Transmission
  57. Neuropathology of Nonmotor Symptoms of Parkinson's Disease
    K. A. Jellinger · 2017 · International review of neurobiology
  58. Inflammasomes: An Emerging Mechanism Translating Environmental Toxicant Exposure Into Neuroinflammation in Parkinson’s Disease
    Faith L. Anderson, Madeleine Coffey, Brent L. Berwin, Matthew C. Havrda · 2018 · Toxicological Sciences
  59. Circulating extracellular vesicles: friends and foes in neurodegeneration
    Riccardo Calvani, Anna Picca, Flora Guerra, Hélio José Coelho-Júnior, Cecilia Bucci, Emanuele Marzetti · 2021 · Neural Regeneration Research
  60. What Is the Evidence that Parkinson’s Disease Is a Prion Disorder, Which Originates in the Gut?
    Małgorzata Kujawska, Jadwiga Jodynis‐Liebert · 2018 · International Journal of Molecular Sciences
  61. Autonomic dysfunction in Parkinson disease and animal models
    Jeanette M. Metzger, Marina Elena Emborg · 2019 · Clinical Autonomic Research
  62. Environmental triggers of Parkinson's disease – Implications of the Braak and dual-hit hypotheses
    Honglei Chen, Keran Wang, Filip Scheperjans, Bryan A. Killinger · 2021 · Neurobiology of Disease
  63. Parkinson disease and progressive supranuclear palsy: protein expression in skin
    Ildefonso Rodríguez‐Leyva, Érika Chi-Ahumada, Juan Carrizales-Rodríguez, Mayela Rodríguez‐Violante, Salvador Velázquez‐Osuna, Verónica Medina‐Mier, María Guadalupe Martel Gallegos, Sergio Zarazúa, Lourdes Enríquez‐Macías, Adriana Castro‐Zavala et al. · 2016 · Annals of Clinical and Translational Neurology
  64. Vaccination strategies in tauopathies and synucleinopathies
    Anne Kristin Braczynski, Jörg Bernhard Schulz, Jan‐Philipp Bach · 2017 · Journal of Neurochemistry
  65. <p>Colonic inflammation affects myenteric alpha-synuclein in nonhuman primates</p>
    Resnikoff, Henry, Metzger, Jeanette M, Lopez, Mary, Bondarenko, Viktoriya, Mejia, Andres, Simmons, Heather A, Emborg, Marina E · 2019 · Journal of Inflammation Research
  66. Impact of aging on animal models of Parkinson's disease
    Ida Hyllen Klæstrup, Mie Kristine Just, Karina Lassen Holm, Aage Kristian Olsen Alstrup, Marina Romero‐Ramos, Per Borghammer, Nathalie Van Den Berge · 2022 · Frontiers in Aging Neuroscience
  67. Rotenone impairs oxidant/antioxidant balance both in brain and intestines in zebrafish
    İsmail Ünal, Ünsal Veli Üstündağ, Perihan Seda Ateş, Gizem Eğilmezer, A. Ata Alturfan, Türkan Yiğitbaşı, Ebru Emekli‐Alturfan · 2018 · International Journal of Neuroscience
  68. Detection and Assessment of α-Synuclein Oligomers in the Urine of Parkinson’s Disease Patients
    Daleum Nam, Jee‐Young Lee, Minhyung Lee, Janghwan Kim, Wongi Seol, Ilhong Son, Dong Hwan Ho · 2020 · Journal of Parkinson s Disease
  69. The Rotenone Models Reproducing Central and Peripheral Features of Parkinson’s Disease
    Ikuko Miyazaki, Masato Asanuma · 2020 · NeuroSci
  70. Molecular and Cellular Interactions in Pathogenesis of Sporadic Parkinson Disease
    Л. П. Долгачева, В. П. Зинченко, Nikolay V. Goncharov · 2022 · International Journal of Molecular Sciences
  71. Effects of HIV-1 Tat on Enteric Neuropathogenesis
    Joy Ngwainmbi, Dipanjana De, Tricia Hardt Smith, Nazira El‐Hage, Sylvia Fitting, Minho Kang, William L. Dewey, Kurt F. Hauser, Hamid I. Akbarali · 2014 · Journal of Neuroscience
  72. The Presence of Alpha‐Synuclein in Skin from Melanoma and Patients with Parkinson's Disease
    Ildefonso Rodríguez‐Leyva, Érika Chi-Ahumada, Manuel Mejía, Juan Pablo Castanedo-Cázares, William Eng, Sami Kameel Saikaly, Juan Carrizales-Rodríguez, Todd Levine, Robert A. Norman, María Esther Jiménez-Capdeville · 2017 · Movement Disorders Clinical Practice
  73. Squalamine Restores the Function of the Enteric Nervous System in Mouse Models of Parkinson’s Disease
    Christine L. West, Yukang Mao, Thilini Delungahawatta, Jessica Y. Amin, Sohana Farhin, Rachel Mai McQuade, Shanti Diwakarla, Ruslan V. Pustovit, Andrew M. Stanisz, John Bienenstock et al. · 2020 · Journal of Parkinson s Disease
  74. Pesticides and the Microbiome-Gut-Brain Axis: Convergent Pathways in the Pathogenesis of Parkinson’s Disease
    Kulcsarova, Kristina, Bang, Corinna, Berg, Daniela, Schaeffer, Eva · 2023 · Journal of Parkinson’s Disease
  75. The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications
    Elisa Menozzi, Anthony H.V. Schapira, Per Borghammer · 2025 · Movement Disorders Clinical Practice
  76. Neuroprotective Effects of Metallothionein Against Rotenone-Induced Myenteric Neurodegeneration in Parkinsonian Mice
    Shinki Murakami, Ikuko Miyazaki, Norio Sogawa, Ko Miyoshi, Masato Asanuma · 2014 · Neurotoxicity Research
  77. Inflammation and Parkinson's disease pathogenesis: Mechanisms and therapeutic insight
    Gianluigi Forloni, Pietro La Vitola, Milica Cerovic, Claudia Balducci · 2020 · Progress in molecular biology and translational science
  78. The association of enteric neuropathy with gut phenotypes in acute and progressive models of Parkinson’s disease
    Rachel Mai McQuade, Lewis M. Singleton, Hongyi Wu, Sophie Hyesuk Lee, Remy Constable, Madeleine R. Di Natale, Mitchell Ty Ringuet, Joel P. Berger, Jessica A. Kauhausen, Clare L. Parish et al. · 2021 · Scientific Reports
  79. Exosomes as Mediators of Chemical-Induced Toxicity
    Dharmin Rokad, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G. Kanthasamy · 2019 · Current Environmental Health Reports
  80. α-Synuclein and nonhuman primate models of Parkinson's disease
    Scott Vermilyea, Marina Elena Emborg · 2015 · Journal of Neuroscience Methods
  81. Relationship among Parkinson’s disease, constipation, microbes, and microbiological therapy
    Xin-Yang Yuan, Yusen Chen, Zhou Liu · 2024 · World Journal of Gastroenterology
  82. Oral subchronic exposure to the mycotoxin ochratoxin A induces key pathological features of Parkinson's disease in mice six months after the end of the treatment
    María Izco, Ariane Vettorazzi, Raquel Forcén, Javier Blesa, María de Toro, Natalia Alvarez-Herrera, J Allen D Cooper, Elena González‐Peñas, Adela López de Ceráin, Lydia Alvarez‐Erviti · 2021 · Food and Chemical Toxicology
  83. Traffic-related air pollution and Parkinson's disease in central California
    Dayoon Kwon, Kimberly C. Paul, Yu Yu, Keren Zhang, Aline Duarte Folle, Jun Yun Wu, Jeff M. Bronstein, Beate R. Ritz · 2023 · Environmental Research
  84. Rifampicin Attenuates Rotenone-Treated Microglia Inflammation via Improving Lysosomal Function
    Liang, Yanran, Zheng, Dezhi, Peng, Sudan, Lin, Danyu, Jing, Xiuna, Zeng, Zhifen, Chen, Ying, Huang, Kaixun, Xie, Yingyu, Zhou, Tianen et al. · 2020 · Toxicology in Vitro
  85. Gut–Brain Axis: Potential Factors Involved in the Pathogenesis of Parkinson's Disease
    Yinxia Chao, Muhammad Yaaseen Gulam, Nicholas Shyh Jenn Chia, Lei Feng, Olaf Rötzschke, Eng‐King Tan · 2020 · Frontiers in Neurology
  86. Brain-gut-microbiota axis in Parkinson’s disease: A historical review and future perspective
    Siyu Dong, Mei Sun, Chuan Hua He, Hong Cheng · 2022 · Brain Research Bulletin
  87. Common mechanisms underlying axonal transport deficits in neurodegenerative diseases: a mini review
    Xiaoman Yang, Zhuoran Ma, Piaopiao Lian, Yan Chun Xu, Xuebing Cao · 2023 · Frontiers in Molecular Neuroscience
  88. Inhibition of Protein Aggregation and Endoplasmic Reticulum Stress as a Targeted Therapy for α-Synucleinopathy
    Natalia Siwecka, Kamil Saramowicz, Grzegorz Galita, Wioletta Rozpędek‐Kamińska, Ireneusz Majsterek · 2023 · Pharmaceutics
  89. Age-Dependent Alpha-Synuclein Accumulation and Phosphorylation in the Enteric Nervous System in a Transgenic Mouse Model of Parkinson’s Disease
    Chong-Bin Zhong, Qian-Qian Chen, Caroline Haikal, Wen Li, Alexander Svanbergsson, Meike Diepenbroek, Jiayi Li · 2017 · Neuroscience Bulletin
  90. Using multi-organ culture systems to study Parkinson’s disease
    Orly Reiner, Tamar Sapir, Arpan Parichha · 2020 · Molecular Psychiatry
  91. Exosomes in Parkinson: Revisiting Their Pathologic Role and Potential Applications
    Yassamine Ouerdane, Mohamed Y. Hassaballah, Abdalrazeq Nagah, Tarek M. Ibrahim, Hosny A. H. Mohamed, Areej El-Baz, Mohamed S. Attia · 2022 · Pharmaceuticals
  92. Long-Term Systemic Exposure to Rotenone Induces Central and Peripheral Pathology of Parkinson’s Disease in Mice
    Shinki Murakami, Ikuko Miyazaki, Ko Miyoshi, Masato Asanuma · 2015 · Neurochemical Research
  93. Live calcium and mitochondrial imaging in the enteric nervous system of Parkinson patients and controls
    An-Sofie Desmet, Carla Cirillo, Jan F. Tack, Wim Vandenberghe, Pieter Vanden Berghe · 2017 · eLife
  94. Is Parkinson’s Disease Truly a Prion-Like Disorder? An Appraisal of Current Evidence
    Aneesha Chauhan, Alexander F. Jeans · 2015 · Neurology Research International
  95. Altered Gut Microbiota in Parkinson’s Disease Patients with Motor Complications
    Takahashi, Kai, Nishiwaki, Hiroshi, Ito, Mikako, Iwaoka, Kazuhiro, Takahashi, Kenta, Suzuki, Yoshio, Taguchi, Keita, Yamahara, Kanako, Tsuboi, Yoshio, Kashihara, Kenichi et al. · 2022 · Parkinsonism & Related Disorders
  96. AMPK-dependent autophagy activation and alpha-Synuclein clearance: a putative mechanism behind alpha-mangostin’s neuroprotection in a rotenone-induced mouse model of Parkinson’s disease
    Pathik Parekh, Nishant Sharma, Monika Sharma, Anagha Gadepalli, Adil Ali Sayyed, Sayan Chatterjee, Abhijeet Sudhir Kate, Amit Khairnar · 2022 · Metabolic Brain Disease
  97. Changes in the sympathetic innervation of the gut in rotenone treated mice as possible early biomarker for Parkinson’s disease
    Mike Arnhold, Yanina Dening, Michaël Chopin, Esteban Arévalo, Mathias Schwarz, Heinz Reichmann, Gabriele Gille, Richard H. W. Funk, Francisco J. Pan-Montojo · 2016 · Clinical Autonomic Research
  98. NF-κB/c-Rel deficiency causes Parkinson’s disease-like prodromal symptoms and progressive pathology in mice
    Edoardo Parrella, Arianna Bellucci, Vanessa Porrini, Marina Benarese, Annamaria Lanzillotta, Gaia Faustini, Francesca Longhena, Giulia Abate, Daniela Letizia Uberti, Marina Pizzi · 2019 · Translational Neurodegeneration
  99. Alzheimer's disease in the gut—Major changes in the gut of 5xFAD model mice with ApoA1 as potential key player
    Nicolai M. Stoye, Malena dos Santos Guilherme, Kristina Endres · 2020 · The FASEB Journal
  100. Parkinson’s disease and translational research
    Elisabeth Dinter, Theodora Saridaki, Leonie Diederichs, Heinz Reichmann, Björn H. Falkenburger · 2020 · Translational Neurodegeneration