PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

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Items 301–400 of 577

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4. Doxorubicin alters the mitochondrial dynamics machinery and mitophagy in the liver of treated animals
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5. Calcium/calmodulin‐dependent protein kinase regulates the PINK1/Parkin and DJ‐1 pathways of mitophagy during sepsis
   Xianghong Zhang, Du Yuan, Qian Sun, Li Xu, Emma J. Lee, Anthony Lewis, Brian Scott Zuckerbraun, Matthew Randall Rosengart · 2017 · The FASEB Journal
6. A Cell-Based High-Throughput Screening Identified Two Compounds that Enhance PINK1-Parkin Signaling
   Shiba-Fukushima, Kahori, Inoshita, Tsuyoshi, Sano, Osamu, Iwata, Hidehisa, Ishikawa, Kei-ichi, Okano, Hideyuki, Akamatsu, Wado, Imai, Yuzuru, Hattori, Nobutaka · 2020 · iScience
7. The principal PINK1 and Parkin cellular events triggered in response to dissipation of mitochondrial membrane potential occur in primary neurons
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8. Lysosomal Storage of Subunit c of Mitochondrial ATP Synthase in Brain-Specific Atp13a2-Deficient Mice
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9. Potential of PINK1 and PARKIN Proteins as Biomarkers for Active Multiple Sclerosis: A Japanese Cohort Study
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11. Generation of phospho‐ubiquitin variants by orthogonal translation reveals codon skipping
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13. Reciprocal Regulation of Mitofusin 2-Mediated Mitophagy and Mitochondrial Fusion by Different PINK1 Phosphorylation Events
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14. Oxidative phosphorylation mediated pathogenesis of Parkinson's disease and its implication via Akt signaling
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15. Carbon Monoxide Stimulates Both Mitophagy And Mitochondrial Biogenesis to Mediate Protection Against Oxidative Stress in Astrocytes
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16. Pathologic and therapeutic implications for the cell biology of parkin
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17. Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells
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18. Pitavastatin activates mitophagy to protect EPC proliferation through a calcium-dependent CAMK1-PINK1 pathway in atherosclerotic mice
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20. Bcl-xL inhibits PINK1/Parkin-dependent mitophagy by preventing mitochondrial Parkin accumulation
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21. LRRK2 Knockout Confers Resistance in HEK-293 Cells to Rotenone-Induced Oxidative Stress, Mitochondrial Damage, and Apoptosis
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24. Phosphorylation of mitochondrial matrix proteins regulates their selective mitophagic degradation
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27. UbMES and UbFluor: Novel probes for ring-between-ring (RBR) E3 ubiquitin ligase PARKIN
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28. Enhanced mitophagy mediated by the YAP/Parkin pathway protects against DOX-induced cardiotoxicity
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30. Substitution of PINK1 Gly411 modulates substrate receptivity and turnover
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40. Mitochondrial fumarate inhibits Parkin-mediated mitophagy
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41. Female genetic distribution bias in mitochondrial genome observed in Parkinson’s Disease patients in northern China
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42. A mechanistic review of Parkin activation
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43. Mitochondrial-Targeted Therapies Require Mitophagy to Prevent Oxidative Stress Induced by SOD2 Inactivation in Hypertrophied Cardiomyocytes
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44. Regulation of mitochondrial cargo-selective autophagy by posttranslational modifications
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45. Emerging role of mitophagy in myoblast differentiation and skeletal muscle remodeling
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46. Systematic Functional Analysis of PINK1 and PRKN Coding Variants
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47. Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization
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49. Nuclear Parkin Activates the ERRα Transcriptional Program and Drives Widespread Changes in Gene Expression Following Hypoxia
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51. PINK1‐mediated mitophagy maintains pluripotency through optineurin
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52. Molecular Signaling to Preserve Mitochondrial Integrity against Ischemic Stress in the Heart: Rescue or Remove Mitochondria in Danger
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54. Lysine 63-linked Polyubiquitination Is Dispensable for Parkin-mediated Mitophagy
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55. PINK1 overexpression protects against cerebral ischemia through Parkin regulation
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56. Excitotoxicity, Oxytosis/Ferroptosis, and Neurodegeneration: Emerging Insights into Mitochondrial Mechanisms
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60. Mitochondrial Dysfunction, Mitophagy and Their Correlation with Perinatal Complications: Preeclampsia and Low Birth Weight
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61. Age-related cataract: GSTP1 ubiquitination and degradation by Parkin inhibits its anti-apoptosis in lens epithelial cells
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62. Guanosine exerts neuroprotective effects by reversing mitochondrial dysfunction in a cellular model of Parkinson’s disease
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63. A PINK1 input threshold arises from positive feedback in the PINK1/Parkin mitophagy decision circuit
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64. BL-918 activates PINK1/Parkin signaling pathway to ameliorate the progression of Parkinson’s disease
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