PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

Shiba-Fukushima, Kahori, Imai, Yuzuru, Yoshida, Shigeharu, Ishihama, Yasushi, Kanao, Tomoko, Sato, Shigeto, Hattori, Nobutaka·2012·Scientific Reports

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  3. Cardiac Autophagy in Sepsis
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  4. Phospho-ubiquitin: upending the PINK–Parkin–ubiquitin cascade
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  7. PINK1 signalling in cancer biology
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  8. Targeting Pink1-Parkin-mediated mitophagy for treating liver injury
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  11. Activation mechanisms of the E3 ubiquitin ligase parkin
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  17. Specificity and disease in the ubiquitin system
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  50. Mitochondrial quality control in neurodegenerative diseases.
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  61. PINK1 phosphorylates ubiquitin predominantly in astrocytes
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