The c-Abl inhibitor, nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson’s disease
Karuppagounder, Senthilkumar S., Brahmachari, Saurav, Lee, Yunjong, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok·2014·Scientific Reports
Cited by (268)
Items 101–200 of 268
- Mitochondrial Aging in the CNS: Unravelling Implications for Neurological Health and DiseaseDavide Steffan, Camilla Pezzini, Martina Esposito, Anaïs Franco‐Romero · 2025 · Biomolecules
- Autophagy and lysosomal pathways in nervous system disordersBaris Bingol · 2018 · Molecular and Cellular Neuroscience
- Tyrosine kinase inhibitors relax pulmonary arteries in human and murine precision-cut lung slicesAnnette Dorothea Rieg, Nina A. Bünting, Christian Cranen, Said Suleiman, Jan Wilhelm Spillner, Heike Schnöring, Thomas Schröder, Saskia Freifrau von Stillfried, Till A. Braunschweig, Paul William Manley et al. · 2019 · Respiratory Research
- Teaching the basics of repurposing mitochondria-targeted drugs: From Parkinson's disease to cancer and back to Parkinson's diseaseBalaraman Kalyanaraman · 2020 · Redox Biology
- Matrix effects in nilotinib formulations with pH-responsive polymer produced by carbon dioxide-mediated precipitationStefano Colombo, Magnus Brisander, Jakob Haglöf, Peter Sjövall, Per Andersson, Jesper Østergaard, Martin Malmsten · 2015 · International Journal of Pharmaceutics
- Therapies to Slow, Stop, or Reverse Parkinson’s DiseaseThomas Foltynie, J. William Langston · 2018 · Journal of Parkinson s Disease
- Poloxamer 188 rescues MPTP‐induced lysosomal membrane integrity impairment in cellular and mouse models of Parkinson's diseaseHongli Dong, Yuanyuan Qin, Yuyu Huang, Dongliang Ji, Feng Wu · 2019 · Neurochemistry International
- Genetic causes of PD: A pathway to disease modificationMarco Toffoli, Sophia R.L. Vieira, Anthony H.V. Schapira · 2020 · Neuropharmacology
- Drug Repurposing for Parkinson’s Disease: The International Linked Clinical Trials experienceSimon Stott, Richard K H Wyse, Patrik Brundin · 2021 · Frontiers in Neuroscience
- Parkin interacting substrate phosphorylation by c-Abl drives dopaminergic neurodegenerationHyojung Kim, Jeong‐Yong Shin, Areum Jo, Ji-Hun Kim, Sangwook Park, Jeong‐Yun Choi, Ho Chul Kang, Valina Lynn Dawson, Ted M. Dawson, Joo‐Ho Shin et al. · 2021 · Brain
- Indoor VOCs exposure induced Parkinson-like behaviors through autophagy dysfunction and NLRP3 inflammasome-mediated neuroinflammationJie Zheng, Yaxian Pang, Yaling Zhang, Wentao Hu, Peihao Yang, Qingping Liu, Jie Ning, Zhe Du, Xiaoting Jin, Jinglong Tang et al. · 2022 · Journal of Hazardous Materials
- Repositioning of drugs for Parkinson’s disease and pharmaceutical nanotechnology tools for their optimizationHéctor Hernández‐Parra, Hernán Cortés, José Arturo Ávalos‐Fuentes, María Luisa Del Prado-Audelo, Benjamín Florán, Gerardo Leyva‐Gómez, Javad Sharifi‐Rad, William Chi Shing Cho · 2022 · Journal of Nanobiotechnology
- Neurodegenerative Diseases: New Hopes and PerspectivesMohammad Aadil Bhat, Suneela Sunil Dhaneshwar · 2023 · Current Molecular Medicine
- In Search of Effective Treatments Targeting α-Synuclein Toxicity in Synucleinopathies: Pros and ConsMaria Fouka, Panagiota Mavroeidi, Grigoria Tsaka, Maria Xilouri · 2020 · Frontiers in Cell and Developmental Biology
- New Era in disease modification in Parkinson's disease: Review of genetically targeted therapeuticsS. Pablo Sardi, Tanya Simuni · 2018 · Parkinsonism & Related Disorders
- Atp7b-dependent choroid plexus dysfunction causes transient copper deficit and metabolic changes in the developing mouse brainClorissa Washington-Hughes, Shubhrajit Roy, Herana Kamal Seneviratne, Senthilkumar S. Karuppagounder, Yulemni Morel, Jace W. Jones, Alex Zak, Tong Xiao, Tatiana N. Boronina, Robert Norman Cole et al. · 2023 · PLoS Genetics
- Old wines in new bottles: Repurposing opportunities for Parkinson's diseaseAshish Kumar Kakkar, Harmanjit Singh, Bikash Medhi · 2018 · European Journal of Pharmacology
- Disease-Modifying Therapies for Multiple System Atrophy: Where Are We in 2022?Victoria Sidoroff, Pam Bower, Nadia Stefanova, Alessandra Fanciulli, Iva Stankovic, Werner H Poewe, Klaus Seppi, Gregor Karl Wenning, Florian Krismer · 2022 · Journal of Parkinson s Disease
- Site-specific mitochondrial dysfunction in neurodegenerationAnežka Vodičková, Shon A. Koren, Andrew P. Wojtovich · 2022 · Mitochondrion
- Nilotinib in Parkinson's disease: A systematic review and meta-analysisXiaolu Xie, Ping Yuan, Liqiu Kou, Xiu Chen, Jun Li, Yaling Li · 2022 · Frontiers in Aging Neuroscience
- Identification and Experimental Validation of Parkinson’s Disease with Major Depressive Disorder Common GenesHuiqing Wang, Shanshan Dou, Chunmei Wang, Wenming Gao, Baohua Cheng, Fuling Yan · 2023 · Molecular Neurobiology
- A current pharmacologic agent versus the promise of next generation therapeutics to ameliorate protein misfolding and/or aggregation diseasesAleksandra Baranczak, Jeffery W. Kelly · 2016 · Current Opinion in Chemical Biology
- The dual role of c‐src in cell‐to‐cell transmission of α‐synucleinYu Ree Choi, Jae‐Bong Kim, Seo‐Jun Kang, Hye Rin Noh, Ilo Jou, Eun-hye Joe, Sang Myun Park · 2020 · EMBO Reports
- Substantial protection against MPTP-associated Parkinson's neurotoxicity in vitro and in vivo by anti-cancer agent SU4312 via activation of MEF2D and inhibition of MAO-BBaojian Guo, Shengquan Hu, Chengyou Zheng, Hongyu Wang, Fangcheng Luo, Haitao Li, Wei Cui, Xifei Yang, Guozhen Cui, Shinghung Mak et al. · 2017 · Neuropharmacology
- c-Abl activates RIPK3 signaling in Gaucher diseaseMaria Jose Yañez, Fabián Campos, Tamara Marín, Andrés D. Klein, Anthony H. Futerman, Alejandra R. Alvarez, Silvana Zanlungo · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Prospects for Disease Slowing in Parkinson DiseaseElisa Menozzi, Anthony H.V. Schapira · 2024 · The Annual Review of Pharmacology and Toxicology
- Molecular Symphony of Mitophagy: Ubiquitin‐Specific Protease‐30 as a Maestro for Precision Management of Neurodegenerative DiseasesAnkit Siwach, Harit Patel, Amit Khairnar, Pathik Parekh · 2025 · CNS Neuroscience & Therapeutics
- Protective role of anticancer drugs in neurodegenerative disorders: A drug repurposing approachDia Advani, Rohan V. Gupta, Rahul S. Tripathi, Sudhanshu Sharma, Rashmi K. Ambasta, Pravir Kumar · 2020 · Neurochemistry International
- Precision Medicine in Parkinson’s Disease: From Genetic Risk Signals to Personalized TherapyGiulia Straccia, Fabiana Colucci, Roberto Eleopra, Roberto Cilia · 2022 · Brain Sciences
- Role of the microtubule-associated TPPP/p25 in Parkinson’s and related diseases and its therapeutic potentialJudit Oláh, Philippe Bertrand, Judit Ovádi · 2017 · Expert Review of Proteomics
- Neurodegenerative diseases: model organisms, pathology and autophagyShwetha Suresh, Vijaya Verma, Shruthi Sateesh, James Premdoss Clement, Ravi R. Manjithaya · 2018 · Journal of Genetics
- LK6/Mnk2a is a new kinase of alpha synuclein phosphorylation mediating neurodegenerationShiqing Zhang, Jiang Xie, Ying Xia, Shu Yu, Zhi-li Gu, Ruili Feng, Guanghong Luo, Dong Wang, Kai Wang, Meng Jiang et al. · 2015 · Scientific Reports
- Nonreceptor Tyrosine Kinase c‐Abl‐Mediated PHB2 Phosphorylation Aggravates Mitophagy Disorder in Parkinson’s Disease ModelYongjiang Zhang, Jiannan Wu, Wei‐Na Jin, Mengmeng Shen, Shiyi Yin, Xiaoyi Lai, Hongxia Ma, Menghan Jiang, Dongxue Sun, Junqiang Yan · 2022 · Oxidative Medicine and Cellular Longevity
- A recent update on drugs and alternative approaches for parkinsonismSneha Kispotta, Debajyoti Das, Shakti Ketan Prusty · 2024 · Neuropeptides
- KSRMF: Kernelized similarity based regularized matrix factorization framework for predicting anti-cancer drug responsesAman Sharma, Rinkle Rani · 2018 · Journal of Intelligent & Fuzzy Systems
- The c-Abl inhibitor in Parkinson diseaseZhihua Zhou, Yunfan Wu, Xue-min Wang, Yongzhu Han · 2017 · Neurological Sciences
- Twelve Years of Drug Prioritization to Help Accelerate Disease Modification Trials in Parkinson’s Disease: The International Linked Clinical Trials InitiativeRichard K H Wyse, Tom Isaacs, Roger A. Barker, Mark Cookson, Ted M. Dawson, David Devos, David Trevor Dexter, Joy Duffen, Howard J. Federoff, Brian K. Fiske et al. · 2024 · Journal of Parkinson s Disease
- Therapeutic innovation in Parkinson’s disease: a 2020 update on disease-modifying approachesDaniele Colombo, Paraskevi Pnevmatikou, Elsa Melloni, Charlotte Keywood · 2020 · Expert Review of Neurotherapeutics
- Negative Conditioning of Mitochondrial Dysfunction in Age-related Neurodegenerative Diseases.Sharmelee Selvaraji, Luting Poh, Venkateswaran Natarajan, Karthik Babu Mallilankaraman, Thiruma Valavan Arumugam · 2019 · PubMed
- Abl depletion via autophagy mediates the beneficial effects of quercetin against Alzheimer pathology across speciesAlfonso Schiavi, Claudia Cirotti, Lora‐Sophie Gerber, Giulia Di Lauro, Silvia Maglioni, Priscila Yumi Tanaka Shibao, Sabrina Montresor, Janine Kirstein, Patrick Petzsch, Karl Köhrer et al. · 2023 · Cell Death Discovery
- Current Nondopaminergic Therapeutic Options for Motor Symptoms of Parkinson's DiseaseJuanjuan Du, Shengdi Chen · 2017 · Chinese Medical Journal
- Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studiesViswanath Das, John Holmes Miller, Alladi Charanraj Goud, Narendran Annadurai, Juan Bautista De Sanctis, Lenka Hrubá, Marián Hajdúch · 2024 · Medicinal Research Reviews
- High-content phenotypic screen to identify small molecule enhancers of Parkin-dependent ubiquitination and mitophagyRoberta Tufi, Emily H. Clark, Tamaki Hoshikawa, Christiana Tsagkaraki, Jack Stanley, Kunitoshi Takeda, James M. Staddon, Thomas Briston · 2023 · SLAS DISCOVERY
- Hybrids of polyphenolic/quinone acids, the potential preventive and therapeutic drugs for PD: Disaggregate α-Syn fibrils, inhibit inclusions, and repair damaged neurons in miceMing-Huan Lü, Zhenping Wang, Li-Zi Xing, Wei Zhang, Feng Han, Guolong Huang, Wei Liu, Yunxiao Zhang, Jinquan Cui, Jinquan Cui · 2023 · European Journal of Medicinal Chemistry
- Kinase-Based Taming of Brain Microglia Toward Disease-Modifying TherapySun Hwa Lee, Kyoungho Suk · 2018 · Frontiers in Cellular Neuroscience
- The c-Abl/p73 pathway induces neurodegeneration in a Parkinson's disease modelTamara Marín, Cristian Valls, Carolina Jerez, Tomás Huerta, Daniela Elgueta, René L. Vidal, Alejandra R. Alvarez, Gonzalo I. Cancino · 2022 · IBRO Neuroscience Reports
- Novel approaches to counter protein aggregation pathology in Parkinson's diseaseSimon Stott, Richard K H Wyse, Patrik Brundin · 2019 · Progress in brain research
- Accelerated Discovery of Novel Ponatinib Analogs with Improved Properties for the Treatment of Parkinson’s DiseaseThomas M. Kaiser, Zackery W. Dentmon, Christopher E. Dalloul, Savita K. Sharma, Dennis C. Liotta · 2020 · ACS Medicinal Chemistry Letters
- Beneficial effects of nilotinib, tyrosine kinase inhibitor on cyclosporine-A induced renal damage in ratsManar A. Nader, Ghalia M. Attia · 2016 · International Immunopharmacology
- Nilotinib Fails to Prevent Synucleinopathy and Cell Loss in a Mouse Model of Multiple System AtrophyMiguel Lopez Cuina, Paul A. Guerin, Marie‐Hélène Canron, Anna Delamarre, Benjamin Dehay, Erwan Bézard, Wassilios G. Meissner, Pierre‐Olivier Fernagut · 2020 · Movement Disorders
- Clinical symptoms, underlying pathogenesis, and the prospect of tailored therapies have all benefited from genetic discoveries in Parkinson's diseaseMoataz Dowaidar · 2021
- Drug Repositioning and Repurposing for Disease-Modifying Effects in Parkinson’s DiseaseSeong Ho Jeong, Phil Hyu Lee · 2025 · Journal of Movement Disorders
- Degradation of alpha-synuclein by dendritic cell factor 1 delays neurodegeneration and extends lifespan in DrosophilaShiqing Zhang, Ruili Feng, Yanhui Li, Linhua Gan, Fangfang Zhou, Shiquan Meng, Qian Li, Tieqiao Wen · 2018 · Neurobiology of Aging
- Recent Advances in Drug Repurposing for Parkinson’s DiseaseXin Chen, Giuseppe Gumina, Kristopher G. Virga · 2018 · Current Medicinal Chemistry
- Enhanced in vivo targeting of estrogen receptor alpha signaling in murine mammary adenocarcinoma by nilotinib/rosuvastatin novel combinationAhmed E. Goda, Alaa E. El‐Sisi, Samia Salem Sokar, Noha M. Abdelrazik · 2020 · Toxicology and Applied Pharmacology
- Glutathione Liposomes Carrying Ceftriaxone, FK506, and Nilotinib to Control Overexpressed Dopamine Markers and Apoptotic Factors in NeuronsYung‐Chih Kuo, He-Cheng Tsai, Rajendiran Rajesh · 2021 · ACS Biomaterials Science & Engineering
- A Novel, Selective c-Abl Inhibitor, Compound 5, Prevents Neurodegeneration in Parkinson’s DiseaseSeung‐Hwan Kwon, Sangjune Kim, A Yeong Park, Saebom Lee, Changdev Gorakshnath Gadhe, Bo Am Seo, Jong Sung Park, Suyeon Jo, Yumin Oh, Sin Ho Kweon et al. · 2021 · Journal of Medicinal Chemistry
- c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and NeurodegenerationAlexis N. Martinez, Cristian M. Lamaizon, Cristian Valls, Fabien Llambi, Nancy R. Leal, Patrick Fitzgerald, Cliff S. Guy, Marcin M. Kamiński, Nibaldo C. Inestrosa, Brigitte van Zundert et al. · 2023 · Antioxidants
- Promising biomarkers and therapeutic targets for the management of Parkinson's disease: recent advancements and contemporary researchMohammad Ahmed Khan, Nafis Haider, Tanveer Singh, Ritam Bandopadhyay, Mohammed M. Ghoneim, Sultan Alshehri, Murtada Taha, Javed Ahmad, Awanish Mishra · 2023 · Metabolic Brain Disease
- Therapeutic potential of Parkin and its regulation in Parkinson’s diseaseNarukkottil Safreena, Indu C. Nair, Goutam Chandra · 2024 · Biochemical Pharmacology
- Preclinical studies and transcriptome analysis in a model of Parkinson’s disease with dopaminergic ZNF746 expressionJi-Hun Kim, Sumin Yang, Hyojung Kim, Dang-Khoa Vo, Han‐Joo Maeng, Areum Jo, Jooheon H. Shin, Joo‐Ho Shin, Hyeon‐Man Baek, Gum Hwa Lee et al. · 2025 · Molecular Neurodegeneration
- The Role of Membrane Affinity and Binding Modes in Alpha-Synuclein Regulation of Vesicle Release and TraffickingTapojyoti Das, Meraj Ramezani, David Snead, Cristian Follmer, Peter J. Chung, Ka Yee Lee, David A. Holowka, Barbara A. Baird, David Eliezer · 2022 · Biomolecules
- c-Abl contributes to glucose-promoted apoptosis via p53 signaling pathway in podocytesYiqiong Ma, Qian Yang, Xinghua Chen, Wei Liang, Zhilong Ren, Guohua Ding · 2016 · Diabetes Research and Clinical Practice
- Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse modelManjeet Kumar, Devanshi Shah, Mridhula Giridharan, Niraj Yadav, Ravi R. Manjithaya, James Premdoss Clement · 2021 · Scientific Reports
- Roles for c-Abl in postoperative neurodegenerationLong Feng, Shihui Fu, Yao Yao, Yulong Li, Longhe Xu, Yali Zhao, Leiming Luo · 2022 · International Journal of Medical Sciences
- An update on novel and emerging therapeutic targets in Parkinson’s diseaseRicha Sawant, Angel Pavalu Godad · 2024 · Metabolic Brain Disease
- Beyond expectations: investigating nilotinib’s potential in attenuating neurodegeneration in Alzheimer’s diseaseDarcy R. Tocci, Maiah Fogel, Vanya Gupta, Peter Sang-Hui Kim, Jean J. Latimer, Aida Adlimoghaddam, Lisa S. Robison, Benedict C. Albensi · 2025 · Alzheimer s Research & Therapy
- A Review on Mitochondrial Dysfunction and Oxidative stress due to Complex-Ⅰ in Parkinson DiseaseVarshini Babu, Navneet Khurana · 2021 · Research Journal of Pharmacology and Pharmacodynamics
- Pre-clinical Aspects and Contemporary Treatments of Parkinson’s DiseasePartosh Chhabra, Rishabh Rishabh, Shivani Singla, Sunayna Choudhary, Shivam Kohli, Nitin Bansal, Seema Bansal · 2023 · CNS & Neurological Disorders - Drug Targets
- Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced miceAmérica Chandía-Cristi, Daniela A. Gutiérrez, Andrés E. Dulcey, Marcelo Lara, Lina Vargas, Yi-Han Lin, Pablo Jimenez-Muñoz, Gabriela Larenas, Xin Xu, Amy Y. Wang et al. · 2024 · Cell Reports
- Cell Biology of Parkin: Clues to the Development of New Therapeutics for Parkinson’s DiseaseJaimin Patel, Nikhil Panicker, Valina Lynn Dawson, Ted M. Dawson · 2022 · CNS Drugs
- Protein kinase inhibitors as therapeutics in neurodegenerative and psychiatric disordersTridente, Giuseppe, Jana, Ankit, Nath, Arnab, Ashraf, Ghulam Md · 2023 · Receptor Tyrosine Kinases in Neurodegenerative and Psychiatric Disorders
- Discovery of 4-methyl-3-(pyridin-2-ylamino)benzamide derivatives as C-Abl inhibitors with potential neuroprotective effectZichao Yang, Yangcheng Ai, Shanhe Wan, Zilong Yang, Honghao Li, Zhonghuang Li, Chunhui Huang, Lishun Zhang, Mingxia Li, Jiajie Zhang et al. · 2022 · Bioorganic & Medicinal Chemistry
- Pharmacological inhibition of AIMP2 aggregation attenuates α-synuclein aggregation and toxicity in Parkinson’s diseaseJeong‐Yong Shin, Bina Lee, Sangwoo Ham, Jihun Kim, Hyojung Kim, Heejeong Kim, Min Gi Jo, Hye Jung Kim, Sang Won Park, Hee‐Seok Kweon et al. · 2022 · Biomedicine & Pharmacotherapy
- Identification of abelson tyrosine kinase inhibitors as potential therapeutics for Alzheimer’s disease using multiple e-pharmacophore modeling and molecular dynamicsRavichand Palakurti, Ramakrishna Vadrevu · 2016 · Journal of Biomolecular Structure and Dynamics
- c-Abl Inhibition Exerts Symptomatic Antiparkinsonian Effects Through a Striatal Postsynaptic MechanismYu Zhou, Yukio Yamamura, Masatoshi Ogawa, Ryosuke Tsuji, Koichiro Tsuchiya, Jiro Kasahara, Satoshi Goto · 2018 · Frontiers in Pharmacology
- Inhibition of ABL1 tyrosine kinase reduces HTLV-1 proviral loads in peripheral blood mononuclear cells from patients with HTLV-1-associated myelopathy/tropical spastic paraparesisDaisuke Kodama, Masakazu Tanaka, Toshio Matsuzaki, Kimiko Izumo, Nobuaki Nakano, Eiji Matsuura, Mineki Saito, Masahiro Nagai, Masahisa Horiuchi, Atae Utsunomiya et al. · 2020 · PLoS neglected tropical diseases
- c‐Abl‐induced Olig2 phosphorylation regulates the proliferation of oligodendrocyte precursor cellsJun Zhang, Jian-guang Sun, Xiaowen Xing, Rong-Rong Wu, Lujun Zhou, Ying Zhang, Fang Yuan, Shukun Wang, Zeng-Qiang Yuan · 2022 · Glia
- A high-affinity cocaine binding site associated with the brain acid soluble protein 1Maged M. Harraz, Adarsha P. Malla, Evan R. Semenza, Maria Shishikura, Manisha Singh, Yun Hwang, In Guk Kang, Young Jun Song, Adele M. Snowman, Pedro Cortés et al. · 2022 · Proceedings of the National Academy of Sciences
- Defying c-Abl signaling circuits through small allosteric compoundsStefania Gonfloni · 2014 · Frontiers in Genetics
- Neurotoxin 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP)-Induced Animal Models of Parkinson’s DiseaseJiro Kasahara, Mohammed Emamussalehin Choudhury, Noriko Nishikawa, Akie Tanabe, Ryosuke Tsuji, Yu Zhou, Masatoshi Ogawa, Hironori Yokoyama, Junya Tanaka, Masahiro Nomoto · 2017 · Elsevier eBooks
- Etiology and pathogenesis of Parkinson diseaseJoseph J. Jankovic, Mark Hallett, Michael S. Okun, Cynthia Comella, Stanley Fahn, Jennifer G. Goldman · 2021 · Elsevier eBooks
- Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson’s DiseaseSangwoo Ham, Heejeong Kim, Jin‐Ha Yoon, Hyojung Kim, Bo Reum Song, Jeong‐Yun Choi, Yun‐Song Lee, Seung‐Mann Paek, Han‐Joo Maeng, Yunjong Lee · 2019 · International Journal of Molecular Sciences
- Repurposing of Kinase Inhibitors to Target c-Abl as Potential Therapeutics for Alzheimer’s DiseaseQingzhang Zhu, Jianchun Chen, Xi Lawrence Wu, Xiaoping Jin, Bing Ruan · 2014 · Journal of Pharmaceutical Innovation
- Evaluation of c-Abl inhibitor vodobatinib in subjects with early Parkinson’s disease: a phase 2, randomized, double-blind, placebo-controlled studyHarini Sarva, Rajesh Pahwa, Jorge Hernández‐Vara, Mark A. Goldstein, Rupam Borgohain, Stewart Alan Factor, Sandeep Inamdar, Damon K. Love, Carrie Hames, Yiyong Fu et al. · 2026 · npj Parkinson s Disease
- Abelson Tyrosine Kinase Inhibitors in Parkinson's Disease and Lewy Body Dementia: A Systematic Review, Meta-analysis, and Meta-regressionGiovanni Gosch Berton, Amanda Cyntia Lima Fonseca Rodrigues, Rafael dos Santos Borges, Nicole Rodrigues Cardoso, Thiago Abrahão de Oliveira, Marcos Vinícius Oliveira Marques · 2024 · Clinical Neuropharmacology
- Disease modifying therapies for Parkinson's disease: Novel targetsNirosen Vijiaratnam, Thomas Foltynie · 2021 · Neuropharmacology
- Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A): Could It Be a Promising Biomarker and Therapeutic Target in Parkinson’s Disease?Sijia Yin, Chao Han, Yun Fei Xia, Fang Jung Wan, Junjie Hu, Liang Kou, Yadi Sun, Jiawei Wu, Yunna Li, Qiulu Zhou et al. · 2022 · Molecular Neurobiology
- Nilotinib, an approved leukemia drug, inhibits smoothened signaling in Hedgehog-dependent medulloblastomaKirti Kandhwal Chahal, Jie Li, Irina Kufareva, Milind Parle, Donald L. Durden, Robert J. Wechsler‐Reya, Clark C. Chen, Ruben A Abagyan · 2019 · PLoS ONE
- Harnessing Drug Repurposing for Exploration of New Diseases: An Insight to Strategies and Case StudiesPriti Jain, Shreyans Kumar Jain, Munendra Jain · 2020 · Current Molecular Medicine
- Review on cerebral malaria—Pathogenesis and role of EphA2 receptor in maintaining blood brain barrier integrityMohd Sayeed Shaikh, Mirza Salman Baig, Syed Sarfaraz Ali, Anas Ahmad, Mohammad Taha Mustafa Shaikh, Paresh R. Mahaparale, Md. Faiyazuddin · 2024 · Health Sciences Review
- Discovery of potential Leonurine-based therapeutic lead MJ210 attenuates Parkinson's disease pathogenesis via NF-κB and MAPK pathways: Mechanistic insights from in vitro and in vivo rotenone modelsSanju Gupta, Moumita Jash, Juhee Khan, Shubham Garg, Rajsekhar Roy, Mohammad Umar Arshi, Prasunpriya Nayak, Surajit Ghosh · 2025 · European Journal of Medicinal Chemistry
- Pathological and clinical aspects of alpha/beta synuclein in Parkinson’s disease and related disordersMichael Tolmasov, Ruth Djaldetti, Nirit Lev, Yossi Gilgun‐Sherki · 2016 · Expert Review of Neurotherapeutics
- The c-Abl inhibitor, nilotinib, as a potential therapeutic agent for chronic cerebellar ataxiaWoo Jin Lee, Jangsup Moon, Tae‐Joon Kim, Jin‐Sun Jun, Han Sang Lee, Young Jin Ryu, Soon‐Tae Lee, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung et al. · 2017 · Journal of Neuroimmunology
- Anticancer drugs for Parkinson's disease: Is it a ray of hope or only hype?Vinay Goyal, Deepa Dash · 2018 · Annals of Indian Academy of Neurology
- An update on the monogenic causes of Parkinson’s disease: Impact on patient stratification and personalised medicineSakeena Asmi, Anand Krishnan, Sneha Mary Alexander, Jimna Mohamed Ameer, T. Nidhish, Sen Chandra Sreetama, Keerthi Tr, Rajesh Anantha Shenoi, S G S Chakravarthy, Goutam Chandra · 2026 · Ageing Research Reviews
- Nilotinib as a Prospective Treatment for Alzheimer’s Disease: Effect on Proteins Involved in Neurodegeneration and Neuronal HomeostasisAnkita Srivastava, Heather A. Renna, Maryann Johnson, Katie Sheehan, Saba Ahmed, Thomas A. Palaia, Aaron Pinkhasov, Irving H. Gomolin, Thomas Wısnıewskı, Joshua De Leon et al. · 2024 · Life
- The Search for Disease Modification in Parkinson’s Disease—A Review of the LiteratureDaniel Barber, Tissa Wijeratne, Lakshman Singh, Kevin Jeffrey Barnham, Colin Louis Masters · 2025 · Life
- Development of 18F-Labeled PET Tracer Candidates for Imaging of the Abelson Non-receptor Tyrosine Kinase in Parkinson’s DiseaseE. Johanna L. Stéen, A Yeong Park, Wissam Beaino, Changdev Gorakshnath Gadhe, Esther J. M. Kooijman, Robert C. Schuit, Maxime Schreurs, Prisca S. Leferink, Jeroen J.M. Hoozemans, Jae Eun Kim et al. · 2023 · Journal of Medicinal Chemistry
- Comparative In silico evaluation of c-Abl inhibitors for Parkinson's disease therapyDevu B. Kumar, Santhosh Kumar Subramanya, Poonam Singh Thakur · 2025 · Biochemical and Biophysical Research Communications