Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry
Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D.·2014·Scientific Reports
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Items 101–130 of 130
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- Neighbouring modifications interfere with the detection of phosphorylated alpha-synuclein at Serine 129: Revisiting the specificity of pS129 antibodiesHilal Ahmed Lashuel, Anne‐Laure Mahul‐Mellier, Salvatore Novello, Ramanath Narayana Hegde, Yllza Jasiqi, Melek Firat Altay, Sonia Donzelli, Sean M. DeGuire, Ritwik Burai, Pedro Magalhães et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Quantitative Profiling of Synuclein Species: Application to Transgenic Mouse Models of Parkinson’s DiseaseSerena Singh, A. Khayachi, A. Milnerwood, Mari L. DeMarco · 2020 · Journal of Parkinson's Disease
- Cracking the code of native amyloid fibrils: advances and next steps to enable pathology-informed therapeutic and diagnosticHilal Ahmed Lashuel · 2026 · Nature Structural & Molecular Biology
- C-terminus-dependent detection of lysosomal alpha-synuclein in nigral Parkinson’s disease human brain neuronsMartino L. Morella, Bana Al Khayrat, Tim E. Moors, Lisanne in ‘t Veld, Irene Frigerio, Vinod Udayar, Bram van der Gaag, Wilma D. J. van de Berg · 2025 · Molecular Neurodegeneration
- Mass spectrometric identification of novel truncated α-synuclein species following optimized immunoprecipitation from human brain tissueKim-Thanh Van, Fatimah Nabeebaccus, Foudil Lamari, Susana Boluda, François Fenaille, Nicolas Villain, François Bécher · 2025 · Analytical Biochemistry
- Quantitative Bioanalysis of Intact Large Molecules using Mass SpectrometryCatherine E. DelGuidice, Omnia A. Ismaiel, William R. Mylott, M. Halquist · 2020
- Hyphenations of one-dimensional capillary liquid chromatography with mass spectrometrySteven Ray Wilson, Henriette Engen Berg, Hanne Røberg‐Larsen, Elsa Lundanes · 2020 · Elsevier eBooks
- Proteoforms in Disease: Biomedical Applications of Top-Down ProteomicsHolden T. Rogers, Z. Gregorich, Megan S. Gant, Zhan Gao, J. Chamot-Rooke, Ying Ge · 2026 · Mass spectrometry reviews (Print)
- Multiplex Immunofluorescent Analysis of Alpha‐Synuclein in Nigral Lewy Bodies With Heat‐Induced Antibody Stripping Reveals an Intricate Multilayered StructureDominik Hraboš, Satomi Hasegawa, D. Koníčková · 2025 · Neuropathology and Applied Neurobiology
- Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodiesD. J. Vidyadhara, D. Bäckström, Risha Chakraborty, J. Ruan, Jae-Min Park, Pramod K. Mistry, S. Chandra · 2024 · Research Square
- Synaptic vesicle endocytosis deficits underlie GBA-linked cognitive dysfunction in Parkinson’s disease and Dementia with Lewy bodiesD. J. Vidyadhara, David C. Bäckström, Risha Chakraborty, Jiapeng Ruan, Jae Min Park, Pramod Kumar Mistry, Sreeganga S. Chandra · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Investigating protein conformational ensembles by native mass spectrometry and complementary biophysical techniques—the case of α-synucleinS. Brocca, E. Ponzini, C. Santambrogio, Rita Grandori · 2026 · Frontiers in Biophysics
- Differently sized soluble α-synuclein species from multiple system atrophy and Lewy body disease brains display different seeding propensitiesS. Zampar, Y. Mei, F. Samuel, M. Karadağ, I. Martínez-Valbuena, N. R. G. Silver, G. Grimmer, S. D. Di Gregorio, A. Tandon, G. Kovacs et al. · 2026 · bioRxiv
- Top-Down versus Bottom-Up Proteomics in Highly Sensitive LC-MS-Based Profiling of Limited SamplesYun-Fan Gao, Michal Greguš, James C. Kostas, Anne-Lise Marie, Alexander R. Ivanov · 2026 · Analytical Chemistry
- N-Terminal Amine Chemistry Influences α-Synuclein Interactions with Lipid BilayersEmily A. E. Brackhahn, Ming-Hao Li, Paola Miranda-Castrodad, H. Lee, J. Musila, David Eliezer, Elizabeth Rhoades · 2026 · Biochemistry
- Structural biology of alpha-synuclein amyloid filaments: Implications in synucleinopathiesPhelippe do Carmo Gonçalves, Irina Fernández, Claudio O. Fernández · 2026 · Journal of Parkinson s Disease
- N-terminal acetylation reduces synuclein pathology in models of Parkinson's diseaseEsther del Cid‐Pellitero, Thomas Goiran, Zaid A.M. Al‐Azzawi, Nathan C. Karpilovsky, Jace Jones-Tabah, Jonas J. Mayo, Frédérique Larroquette, Wen Luo, Irina Shlaifer, Yogitha Thattikota et al. · 2026 · Neurobiology of Disease
- Parkinson's disease and appendix: a hidden kinshipHetvi Patel, Maitry H. Rathod, Bisojeet R. Khandai, A. Vyas · 2026 · International Journal of Basic & Clinical Pharmacology
- Comprehensive Analysis of Autophagy-Related Gene Profiles and Immune Characteristics in Parkinson’s DiseaseLei Yu, Meimei Guo, Shilin Zhang, Yutuo Zheng, Jiawei Hao, Yuhan Liu, Jiabin Zhou · 2026 · ACS Chemical Neuroscience
- Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patientsEhraz Anis, Saima Zameer, Josh Wierenga, Peipei Li, Jacek W. Sikora, Juozas Gordevičius, Meghan Schilthuis, Richard D. LeDuc, Jeffrey H. Kordower, Michelle A. Pinho et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Residues 2-7 of α-synuclein regulate amyloid formation via lipid-dependent and -independent pathwaysKatherine M Dewison, B. Rowlinson, Jonathan M Machin, J. Crossley, Dev Thacker, M. Wilkinson, Sabine M. Ulamec, G. N. Khan, N. Ranson, P. van Oosten-Hawle et al. · 2024 · bioRxiv
- Software-Assisted Data Processing Workflow for Intact Glycoprotein Mass SpectrometryAlan B. Moran, E. Domínguez-Vega, M. Wuhrer, G. Lageveen-Kammeijer · 2023 · Journal of Proteome Research
- Aggregation of alpha-synuclein using single-molecule spectroscopyMarija Iljina · 2017
- Mass spectrometric analysis of Lewy body-enriched -synuclein in Parkinson’s diseasePayel, Bhattacharjee, Annika, Öhrfelt, Tammaryn, Lashley, Kaj, Blennow, Ann, Brinkmalm et al. · 2019