Quantitative Measurement of Intact Alpha-Synuclein Proteoforms from Post-Mortem Control and Parkinson's Disease Brain Tissue by Intact Protein Mass Spectrometry

Kellie, John F., Higgs, Richard E., Ryder, John W., Major, Anthony, Beach, Thomas G., Adler, Charles H., Merchant, Kalpana, Knierman, Michael D.·2014·Scientific Reports

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  19. Differently sized soluble α-synuclein species from multiple system atrophy and Lewy body disease brains display different seeding propensities
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  20. Top-Down versus Bottom-Up Proteomics in Highly Sensitive LC-MS-Based Profiling of Limited Samples
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  23. N-terminal acetylation reduces synuclein pathology in models of Parkinson's disease
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  26. Aggregation-prone alpha-synuclein proteoforms and dysregulated molecular signatures in the vermiform appendix of synucleinopathy patients
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  27. Residues 2-7 of α-synuclein regulate amyloid formation via lipid-dependent and -independent pathways
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  29. Aggregation of alpha-synuclein using single-molecule spectroscopy
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  30. Mass spectrometric analysis of Lewy body-enriched -synuclein in Parkinson’s disease
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