Cross-talk between signaling pathways: The link between plant secondary metabolite production and wounding stress response
Open accessAbstract
Plants subjected to wounding stress produce secondary metabolites. Several of these metabolites prevent chronic diseases and can be used as colorants, flavors and as antimicrobials. This wound-induced production of plant secondary metabolites is mediated by signaling-molecules such as reactive oxygen species (ROS), ethylene (ET) and jasmonic acid (JA). However, their specific role and interactions that modulate the wound-respond in plants is not fully understood. In the present study, a subtractive cDNA library was generated, to better understand the global response of plants to wounding stress. Carrot (Daucus carota) was used as a model system for this study. A total of 335 unique expressed sequence tags (ESTs) sequences were obtained. ESTs sequences with a putative identity showed involvement in stress-signaling pathways as well as on the primary and secondary metabolism. Inhibitors of ROS biosynthesis, ET action and JA biosynthesis alone and in combination were applied to wounded-carrots in order to determine, based on relative gene expression data, the regulatory role of ET, JA and ROS on the wound-response in plants. Our results demonstrate that ROS play a key role as signaling-molecules for the wound-induced activation of the primary and secondary metabolism whereas ET and JA are essential to modulate ROS levels.
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Mechanical damage to either aerial or root tissue is known to activate the plant defense response and stimulate the production of secondary metabolites.
“Mechanical damage to either aerial or root tissue is known to activate the plant defense response and stimulate the production of secondary metabolites [28].”
From Ecdysteroid Content and Therapeutic Activity in Elicited Spinach Accessions (2020) · cites this paper as [28]
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Research works printed but not linked: 1
- Surjadinata B. B. Wounding and ultraviolet radiation stresses affect the phenolic profile and antioxidant capacity of carrot tissue. PhD Dissertation, Texas A&M University. pp 120 (2006).
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Ecdysteroid Content and Therapeutic Activity in Elicited Spinach Accessions
Gorelick, J., Iraqi, R. H., & Bernstein, N. (2020) · Plants · doi:10.3390/plants9060727 · Cited by 19 · see citing works
- Authors
- Jacobo-Velázquez, D. A., González-Agüero, M., & Cisneros-Zevallos, L.
- Affiliations
- Instituto de Investigaciones Agropecuarias (CL)
- Venue
- Scientific Reports
- Published
- 2015-02-25
- Volume
- 5
- Issue
- 1
- Pages
- 8608-8608
- ISSN
- 2045-2322 (ISSN-L)
- PMC
- PMC5390084
- OpenAlex
- W2025979008
- Cited by
- 238
- References
- 32
- Citations by year
- 2026: 14 · 2025: 21 · 2024: 20 · 2023: 22 · 2022: 28 · 2021: 27 · 2020: 27 · 2019: 22 · 2018: 16 · 2017: 17 · 2016: 21 · 2015: 3
- FWCI
- 22.95
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Locations
- Scientific Reports (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- OakTrust (Texas A&M University Libraries) (submittedVersion)
- Funders
- U.S. Department of Agriculture
- Texas AgriLife Research
- Consejo Nacional de Ciencia y Tecnología
- Cooperative State Research, Education, and Extension Service
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Stress Responses and Tolerance
- Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect-Plant Interactions and Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Keywords
- plant secondary metabolites, reactive oxygen species, ethylene, jasmonic acid, signaling crosstalk, carrot, expressed sequence tags, subtractive cDNA library, gene expression, primary metabolism
- MeSH terms
- Basal Metabolism, Cyclopentanes, Ethylenes, Models, Biological, Phenols, Plants, Stress, Physiological, Wounds and Injuries, Signal Transduction, Gene Library, Reactive Oxygen Species, Gene Expression Regulation, Plant, Daucus carota, Oxylipins, Secondary Metabolism
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