Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes

Cited by (240)

Items 101–200 of 240

1. Increased plasma nesfatin-1 levels may be associated with corticosterone, IL-6, and CRP levels in patients with major depressive disorder
   Qingrong Xia, Jun Liang, Yin Cao, Feng Shan, Yang Liu, Yayun Xu · 2018 · Clinica Chimica Acta
2. Gut microbiota in mental health and depression: role of pre/pro/synbiotics in their modulation
   Hasnain N. Methiwala, Bhupesh Vaidya, Vamsi Krishna Addanki, Mahendra Bishnoi, Shyam Sunder Sharma, Kanthi Kiran Kondepudi · 2021 · Food & Function
3. Central and peripheral nervous systems: master controllers in cancer metastasis
   Ming Shi, Dan Liu, Zhengyan Yang, Ning Guo · 2013 · Cancer and Metastasis Reviews
4. Blood-based biomarkers predicting response to antidepressants
   Yasmin Busch, Andreas Menke · 2018 · Journal of Neural Transmission
5. PDE11A negatively regulates lithium responsivity
   Girish Pathak, Michael J. Agostino, Katherine Bishara, William R. Capell, J L Fisher, Shweta Hegde, Baher A. Ibrahim, Katy Pilarzyk, Crawford Sabin, T Tuczkewycz et al. · 2016 · Molecular Psychiatry
6. A review on antidepressant effect of medicinal plants
   Zahra Rabiei, Sana Rabiei · 2017 · Bangladesh Journal of Pharmacology
7. Knockdown of hippocampal cysteinyl leukotriene receptor 1 prevents depressive behavior and neuroinflammation induced by chronic mild stress in mice
   Xuben Yu, Rongrong Dong, Hui Wang, Jingran Lin, Yunqi An, Yong Du, Susu Tang, Mei Ying Hu, Yan Long, Hongbin Sun et al. · 2015 · Psychopharmacology
8. Depression in myasthenia gravis: a heterogeneous and intriguing entity
   Yury V. Gavrilov, Tatjana M. Alekseeva, O. A. Kreis, Philipp O. Valko, Konrad Peter Weber, Yulia Valko · 2020 · Journal of Neurology
9. Interleukin-6 amplifies glucagon secretion: coordinated control via the brain and pancreas
   Tammy M. Barnes, Yolanda F. Otero, Amicia D. Elliott, Alicia D. Locke, Carlo M. Malabanan, Anastasia Coldren, Marcela Briššová, David W. Piston, Owen P. McGuinness · 2014 · American Journal of Physiology-Endocrinology and Metabolism
10. Higher Levels of Pro-inflammatory Cytokines Are Associated With Higher Levels of Glutamate in the Anterior Cingulate Cortex in Depressed Adolescents
    Ho, Tiffany C., Teresi, Giana I., Segarra, Jillian R., Ojha, Amar, Walker, Johanna C., Gu, Meng, Spielman, Daniel M., Sacchet, Matthew D., Jiang, Fei, Rosenberg-Hasson, Yael et al. · 2021 · Frontiers in Psychiatry
11. Interferon-α exacerbates neuropsychiatric phenotypes in lupus-prone mice
    Jing Zeng, Xinyu Meng, Ping Zhou, Zhihua Yin, Qinglian Xie, Hong Zou, Nan Shen, Zhizhong Ye, Yuanjia Tang · 2019 · Arthritis Research & Therapy
12. Thymoquinone Loaded Solid Lipid Nanoparticles Demonstrated Antidepressant-Like Activity in Rats via Indoleamine 2, 3- Dioxygenase Pathway
    Mohammad Mahtab Alam, Saima Zameer, Abul Kalam Najmi, Farhan Jalees Ahmad, Syed Sarim Imam, Mohd Akhtar · 2020 · Drug Research
13. Minocycline attenuates depressive-like behaviors in mice treated with the low dose of intracerebroventricular streptozotocin; the role of mitochondrial function and neuroinflammation
    Haniyeh Mozafari, Shayan Amiri, Shahram Ejtemaei Mehr, Majid Momeny, Hossein Amini-Khoei, Soroush Bijani, Mir-Jamal Hosseini · 2020 · Molecular Biology Reports
14. The translational aspect of complementary and alternative medicine for cancer with particular emphasis on Kampo
    Marie S. Amitani · 2015 · Frontiers in Pharmacology
15. Candidate Strategies for Development of a Rapid-Acting Antidepressant Class That Does Not Result in Neuropsychiatric Adverse Effects: Prevention of Ketamine-Induced Neuropsychiatric Adverse Reactions
    Motohiro Okada, Yasuhiro Kawano, Kouji Fukuyama, Eishi Motomura, Takashi Shiroyama · 2020 · International Journal of Molecular Sciences
16. Accumulation of Senescent Neural Cells in Murine Lupus With Depression-Like Behavior
    Yuki Saito, Maki Miyajima, Sena Yamamoto, Tsukasa Sato, Norihiro Miura, Mineko Fujimiya, Takako Chikenji · 2021 · Frontiers in Immunology
17. Evaluation of interleukin‐6 and serotonin as biomarkers to predict response to fluoxetine
    Aarthi Manoharan, Ravi Philip Rajkumar, Deepak Gopal Shewade, Rajan Sundaram, Avin Muthuramalingam, Abialbon Paul · 2016 · Human Psychopharmacology Clinical and Experimental
18. Suppressive effects of the supercritical-carbon dioxide fluid extract of Chrysanthemum indicum on chronic unpredictable mild stress-induced depressive-like behavior in mice.
    Xiaoli Wu, Benqin Tang, Xian Liao, Zi-Ren Su, S. Lee, Ye-Feng Cai, Chuwen Li · 2019 · Food & Function
19. Interaction of the immune-inflammatory and the kynurenine pathways in rats resistant to antidepressant treatment in model of depression
    Weronika Duda, Katarzyna Curzytek, Marta Kubera, Thomas J. Connor, Eimear M. Fagan, Agnieszka Basta‐Kaim, Ewa Trojan, Mariusz Papp, Piotr Gruca, Bogusława Budziszewska et al. · 2019 · International Immunopharmacology
20. Transgenic mice with increased astrocyte expression of IL-6 show altered effects of acute ethanol on synaptic function
    Ruben V. Hernandez, A. Puro, Jessica C. Manos, Salvador Huitrón‐Reséndiz, Kenneth C. Reyes, Kevin Liu, Khanh Vo, Amanda J. Roberts, Donna L. Gruol · 2015 · Neuropharmacology
21. Immunomodulatory activity of ketamine in human astroglial A172 cells: Possible relevance to its rapid antidepressant activity
    Yael Yuhas, Shai Ashkenazi, Eva Berent, Abraham Weizman · 2015 · Journal of Neuroimmunology
22. Poly (ADP-ribose) polymerase-1 inhibitor, 3-aminobenzamide pretreatment ameliorates lipopolysaccharide-induced neurobehavioral and neurochemical anomalies in mice
    Chandra Shaker Sriram, Ashok Jangra, Satendra Singh Gurjar, Md. Iftikar Hussain, Probodh Borah, Mangala Lahkar, Pritam Mohan, Babul Kumar Bezbaruah · 2015 · Pharmacology Biochemistry and Behavior
23. An altered peripheral IL6 response in major depressive disorder
    Kelli M. Money, Zita Galik-Olah, Željka Korade, Krassimira A. Garbett, Richard Charles Shelton, Károly Mirnics · 2016 · Neurobiology of Disease
24. Novel Treatment Targets Based on Insights in the Etiology of Depression: Role of IL-6 Trans-Signaling and Stress-Induced Elevation of Glutamate and ATP
    Hans O. Kalkman · 2019 · Pharmaceuticals
25. Systemic immunization with altered myelin basic protein peptide produces sustained antidepressant-like effects
    Ying Han, Cheng-Yu Sun, Shiqiu Meng, Serik Tabarak, Kai Yuan, Lu Cao, Wei Yan, Lingzhi Xu, Jiahui Deng, Weili Zhu et al. · 2019 · Molecular Psychiatry
26. Could a blood test for PTSD and depression be on the horizon?
    Dario Aspesi, Graziano Pinna · 2018 · Expert Review of Proteomics
27. Interleukin 6 as a pathogenic factor mediating clinical manifestations and a therapeutic target for rheumatic diseases and depressive disorders
    Tatyana Andreyevna Lisitsyna, Dmitry Yu. Veltishchev, Aleksander M. Lila, Evgeny Lvovich Nasonov · 2019 · Rheumatology Science and Practice
28. Water extract of Armillaria mellea (Vahl) P. Kumm. Alleviates the depression-like behaviors in acute- and chronic mild stress-induced rodent models via anti-inflammatory action
    Yu‐En Lin, Hsiang-Lan Wang, Kuan‐Hung Lu, Yun‐Ju Huang, Suraphan Panyod, Wei-Ting Liu, Shuhui Yang, Mei-Hsing Chen, Yun‐Shen Lu, Lee‐Yan Sheen · 2020 · Journal of Ethnopharmacology
29. Improvement of astrocytic gap junction involves the anti-depressive effect of celecoxib through inhibition of NF-κB
    Xiao-xi Zheng, Chengfeng Zhang, Li-qing Li, Jun-rui Ye, Siyu Ren, Zhao Zhang, Xin He, Shifeng Chu, Nai‐Hong Chen · 2024 · Brain Research Bulletin
30. Potential value of Interleukin-6 as a diagnostic biomarker in human MDD and the antidepressant effect of its receptor antagonist tocilizumab in lipopolysaccharide-challenged rats
    Dandan Xu, Yayun Xu, Xinran Gao, Mengyu Yan, Chen Zhang, Xian Wu, Qingrong Xia, Jin‐Fang Ge · 2023 · International Immunopharmacology
31. Inflammation and internalizing disorders in adolescents
    Cristiano Tschiedel Belem da Silva, Marianna de Abreu Costa, Flávio Pereira Kapczinski, Bianca Wollenhaupt de Aguiar, Giovanni Abrahão Salum, Gisele Gus Manfro · 2017 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
32. Antidepressant‐Like Effect of Lipid Extract of Channa striatus in Chronic Unpredictable Mild Stress Model of Depression in Rats
    Mohamed Saleem Abdul Shukkoor, Mohamad Taufik Hidayat Baharuldin, Abdul Manan Mat Jais, Mohamad Aris Mohd Moklas, Sharida Fakurazi · 2016 · Evidence-based Complementary and Alternative Medicine
33. Controversies about a common etiology for eating and mood disorders
    Clara Rossetti, Olivier Halfon, Benjamin Boutrel · 2014 · Frontiers in Psychology
34. Serum Cortisol, Nesfatin-1, and IL-1β: Potential Diagnostic Biomarkers in Elderly Patients with Treatment-Resistant Depression
    Xiaoping Wu, Biao Dai, Fanfan Yan, Yang Chen, Yayun Xu, Qingrong Xia, Xulai Zhang · 2022 · Clinical Interventions in Aging
35. Altered brain activity during withdrawal from chronic alcohol is associated with changes in IL-6 signal transduction and GABAergic mechanisms in transgenic mice with increased astrocyte expression of IL-6
    Donna L. Gruol, Salvador Huitrón‐Reséndiz, Amanda J. Roberts · 2018 · Neuropharmacology
36. Strategies for Treatment-Resistant Depression: Lessons Learned from Animal Models
    Gislaine Z. Réus, Airam Barbosa de Moura, Laura Araújo Borba, Helena M. Abelaira, João Quevedo · 2019 · Complex Psychiatry
37. Prolonged STAT1 activation in neurons drives a pathological transcriptional response
    Danielle N. Clark, Shane M. O’Neil, Li Xu, Justin T. Steppe, Justin T Savage, Kavya Raghunathan, Anthony J. Filiano · 2023 · Journal of Neuroimmunology
38. Chronic high dose of captopril induces depressive-like behaviors in mice: possible mechanism of regulatory T cell in depression
    Hyun-Sun Park, Arum Han, Hye-Lim Yeo, Min-Jung Park, Min‐Jung You, Hyun Jin Choi, Chang-Won Hong, Sang‐Hyuk Lee, Seung Hyun Kim, Borah Kim et al. · 2017 · Oncotarget
39. Genome-wide analysis of LPS-induced inflammatory response in the rat ventral hippocampus: Modulatory activity of the antidepressant agomelatine
    A.C. Rossetti, Maria Serena Paladini, Giorgio Racagni, Marco Andrea Riva, Annamaria Cattaneo, Raffaella Molteni · 2017 · The World Journal of Biological Psychiatry
40. Peripheral Biomarkers of Inflammation in Depression: Evidence from Animal Models and Clinical Studies
    João Paulo Brás, Soraia Filipa Tavares Pinto, Maria Inês Almeida, Joana Prata, Orlando von Doellinger, Rui C. Coelho, Mário Adolfo Barbosa, Susana Gomes Santos · 2019 · Methods in molecular biology
41. Cashew (Anacardium occidentale) Extract: Possible Effects on Hypothalamic–Pituitary–Adrenal (HPA) Axis in Modulating Chronic Stress
    Guedang Nyayi Simon Désiré, Foyet Harquin Simplice, Guillaume Woumitna Camdi, Fatima Zahra Kamal, Parfait Bouvourné, Tchinda Defo Serge Hermann, Ngatanko Abaïssou Hervé Hervé, Eglantine Keugong Wado, Jorelle Linda Damo Kamda, Roland Nhouma Rebe et al. · 2023 · Brain Sciences
42. An augmentation study of MSI-195 (S-adenosylmethionine) in Major Depressive Disorder
    Steven D. Targum, Beth R. Cameron, Ludvina Ferreira, I. David MacDonald · 2018 · Journal of Psychiatric Research
43. Biological Evaluation of Aegle marmelos Fruit Extract and Isolated Aegeline in Alleviating Pain–Depression Dyad: In Silico Analysis of Aegeline on MAO-A and iNOS
    Amritpal Singh, Lovedeep Singh, Palwinder Singh, Rajbir Bhatti · 2021 · ACS Omega
44. Choline Supplementation Alters Hippocampal Cytokine Levels in Adolescence and Adulthood in an Animal Model of Fetal Alcohol Spectrum Disorders
    Jessica A. Baker, Tamara S. Bodnar, Kristen R. Breit, Joanne Weinberg, Jennifer Dolan Thomas · 2023 · Cells
45. The role of interleukin genes in the course of depression
    Monika Ewa Talarowska, Janusz Szemraj, Piotr Gałecki · 2016 · Open Medicine
46. Infection and chronic disease activate a brain-muscle signaling axis that regulates muscle performance
    Shuo Yang, Meijie Tian, Yulong Dai, Shengyong Feng, Yunyun Wang, Deepak Chhangani, Tiffany Ou, Wenle Li, Ze Hua Yang, Jennifer F. McAdow et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
47. Identification of a microglial activation-dependent antidepressant effect of amphotericin B liposome
    Minhui Gao, Peili Hu, Zixuan Cai, Yue Hui Wu, Dan Wang, Wenfeng Hu, Xing Xu, Ya-Ru Zhang, Xu Lu, Dongjian Chen et al. · 2019 · Neuropharmacology
48. Acupuncture alters pro-inflammatory cytokines in the plasma of maternally separated rat pups
    Dongsoo Kim, Chang‐Hwan Bae, Ye Lee Jun, Hyongjun Jeon, Sungtae Koo, Seungtae Kim · 2017 · Chinese Journal of Integrative Medicine
49. Association of plasma cytokines and antidepressant response following mild-intensity whole-body hyperthermia in major depressive disorder
    Michael C. Flux, David Glenn Smith, John J. B. Allen, Matthias R. Mehl, Andi Medrano, Tommy K. Begay, Brandon H. Middlemist, Brandon M. Marquart, Steven P. Cole, Christina J. Sauder et al. · 2023 · Translational Psychiatry
50. Cannabidiol prevents lipopolysaccharide-induced sickness behavior and alters cytokine and neurotrophic factor levels in the brain
    Pedro Augusto Lopes Tito, Túlio Cézar de Souza Bernardino, Paula Maria Quaglio Bellozi, Maria Carolina Machado da Silva, Aline Silva de Miranda, Érica Leandro Marciano Vieira, Fabrício A. Moreira, András Palotás, Antônio Carlos Pinheiro de Oliveira, Helton José Reis · 2021 · Pharmacological Reports
51. Neural Mechanisms of Exercise: Effects on Gut Miccrobiota and Depression
    Ti‐Fei Yuan, Nuno Rocha, Flávia Paes, Óscar Arias-Carrión, Sergio Eduardo de Carvalho Machado, Alberto Souza Sá Filho · 2015 · CNS & Neurological Disorders - Drug Targets
52. Future Viable Models of Psychiatry Drug Discovery in Pharma
    Stacey J. Sukoff Rizzo, Jeremy R. Edgerton, Zoë A. Hughes, Nicholas J. Brandon · 2013 · SLAS DISCOVERY
53. Suppressive Effects of Isofraxidin on Depressive-like Behaviors Induced by Chronic Unpredictable Mild Stress in Mice
    Xiaoli Wu, Jingwen Gu, Zhi-Sheng Zou, Meng Yu, Chen Zhang, Qinghui Xiao, Xin Chen, Chu-Wen Li · 2022 · Brain Science
54. miRNAs in treatment-resistant depression: a systematic review
    Lun Cai, Jingwen Xu, Jie Liu, Huazheng Luo, Rongrong Yang, Xiongbin Gui, Liping Wei · 2024 · Molecular Biology Reports
55. Mechanistic insights into the anti-depressant effect of emodin: an integrated systems pharmacology study and experimental validation
    Peng Hui Zeng, Xiaoming Wang, Chao‐Yuan Ye, Hong-Fei Su, Ying‐Yan Fang, Teng Zhang, Qing Tian · 2021 · Aging
56. Clinical and Biological Factors Are Associated with Treatment-Resistant Depression
    Massimiliano Buoli, Enrico Capuzzi, Alice Caldiroli, Alessandro Ceresa, Cecilia Maria Esposito, Cristina Posio, Anna Maria Auxilia, Martina Capellazzi, Ilaria Tagliabue, Teresa Surace et al. · 2022 · Behavioral Sciences
57. Activation of indoleamine 2, 3- dioxygenase pathway by olanzapine augments antidepressant effects of venlafaxine in mice
    Jaya Thomas, Razia Khanam, Divya Vohora · 2017 · Psychiatry Research
58. Effects of age and social isolation on murine hippocampal biochemistry and behavior
    Annabelle Panossian, Michael W. Cave, Bhavik Anil Patel, Emily L. Brooks, Melanie Sarah Flint, Mark S. Yeoman · 2020 · Mechanisms of Ageing and Development
59. Attenuation of the levels of pro-inflammatory cytokines prevents depressive-like behavior during ethanol withdrawal in mice
    E.B. Fraga-Junior, Isadora Luiza Fernandes, Christopher Alecsander Herane Rohden, Diego Luiz Doneda, H.N. Ynoue, Fabrício Rios-Santos, E. Lima, Z.S. Buss, Samuel Vandresen-Filho · 2022 · Brain Research Bulletin
60. Hippocampal Inflammation and Gene Expression Changes in Peripheral Lipopolysaccharide Challenged Mice Showing Sickness and Anxiety-Like Behaviors
    Sumire Matsuura, Yuki Nishimoto, Akane Endo, Hirono Shiraki, Kanzo Suzuki, Eri Segi‐Nishida · 2023 · Biological and Pharmaceutical Bulletin
61. Toothbrushing and School Refusal in Elementary School: A Longitudinal Study
    Yoshifumi Fukuya, Yusuke Matsuyama, Aya Isumi, Satomi Kato Doi, Manami Ochi, Takeo Fujiwara · 2020 · International Journal of Environmental Research and Public Health
62. Antidepressants upregulate c-Fos expression in the lateral entorhinal cortex and hippocampal dorsal subiculum: study in rats.
    I. Ionov, Irina I. Pushinskaya, Niсholas P Gorev, David D. Frenkel · 2019 · Brain Research Bulletin
63. Glucocorticoids attenuate interleukin‐6‐induced c‐Fos and Egr1 expression and impair neuritogenesis in PC12 cells
    Hannes Bongartz, Elena A. Seiß, Jörg Bock, Fred Schaper · 2021 · Journal of Neurochemistry
64. Interleukin 6 trans-signaling regulates basal synaptic transmission and sensitivity to pentylenetetrazole-induced seizures in mice
    Roberto Cuevas‐Olguin, Eric Esquivel‐Rendon, Jorge Vargas‐Mireles, Francisco García‐Oscos, Marcela Miranda‐Morales, Humberto Salgado, Stefan Rose‐John, Marco Atzori · 2017 · Synapse
65. IL-6 and IL-10 levels in the umbilical cord blood of newborns with a history of crack/cocaine exposure in utero: a comparative study
    Victor Mardini, Luís Augusto Rohde, Keila Maria Mendes Ceresér, Carolina Gubert, Emily Galvão da Silva, Fernando Xavier, Rodrigo Ritter Parcianello, Liane Marise Röhsig, Flávio Pechansky, Thiago Gatti Pianca et al. · 2016 · Trends in Psychiatry and Psychotherapy
66. Biomedical Implications of Plant-based Principles as Antidepressants: Prospects for Novel Drug Development
    Khushboo, Abhishek Kumar, Bechan Sharma · 2021 · Mini-Reviews in Medicinal Chemistry
67. The Role of Mitochondrial Dysfunction-Mediated Changes in Immune Cytokine Expression in the Pathophysiology and Treatment of Major Depressive Disorder
    Wanjun Zhang, Tianyi Wang, Lei Li, Jiyi Xu, Jing Wang, Gang Wang, Jing Du · 2025 · Molecular Neurobiology
68. Lipopolysaccharide‐induced sickness behavior is not altered in male Fmr1 ‐deficient mice
    Danielle Santana‐Coelho, Samantha L. Hodges, Saul Ivan Quintero, Paige D. Womble, D. Gregory Sullens, David A. Narvaiz, Rebecca Herrera, Melanie J. Sekeres, Joaquín N. Lugo · 2023 · Brain and Behavior
69. Chronic stress causes neuroendocrine-immune disturbances without affecting renal vitamin D metabolism in rats
    Pei Jiang, L. Zhang, Wen-Ye Zhu, Hongru Li, Ruili Dang, Mimi Tang · 2014 · Journal of Endocrinological Investigation
70. Antidepressant‐Like Effect of Lipid Extract of Channa striatus in Postpartum Model of Depression in Rats
    Mohamed Saleem Abdul Shukkoor, Mohamad Taufik Hidayat Baharuldin, Abdul Manan Mat Jais, Mohamad Aris Mohd Moklas, Sharida Fakurazi, Rusliza Basir · 2017 · Evidence-based Complementary and Alternative Medicine
71. Associations of plasma interleukin-6 with plasma and cerebrospinal fluid monoamine biosynthetic pathway metabolites in treatment-resistant depression
    Manivel L. Rengasamy, Lora Lee McClain, Pranali Gandhi, Anna Maria Segreti, David A. Brent, David Gerard Peters, Lisa A. Pan · 2018 · Neurology Psychiatry and Brain Research
72. Impact of Elevated Brain IL-6 in Transgenic Mice on the Behavioral and Neurochemical Consequences of Chronic Alcohol Exposure
    Donna L. Gruol, Delilah Calderon, Salvador Huitrón‐Reséndiz, Chelsea Cates‐Gatto, Amanda J. Roberts · 2023 · Cells
73. Advances of Endothelial Progenitor Cells in the Development of Depression
    Nana Yang, Shiyu Sun, Guangqing Duan, Kaixuan Lv, Chen Liang, Linlin Zhang, Jielun Yu, Yaohui Tang, Guohua Lü · 2021 · Frontiers in Cellular Neuroscience
74. Cognitive impairment induced by permanent bilateral common carotid occlusion exacerbates depression-related behavioral, biochemical, immunological and neuronal markers
    Fatemeh Khojasteh, Arezo Nahavandi, Sara Mehrpouya, Judith Regina Homberg, Solmaz Mirzamohammadi, Safoora Raufi, Mansoureh Soleimani, Mahmood Barati · 2014 · Brain Research
75. Immunomodulatory and behavioral effects of ayahuasca and N, N-dimethyltryptamine in a rat model of lipopolysaccharide-induced depression
    Daniel do Nascimento Sousa, Monique de Abreu Azevedo, Maria Lucília dos Santos, Tatiana Karla dos Santos Borges, Daniela Mara de Oliveira, Eloísa Dutra Caldas · 2025 · Metabolic Brain Disease
76. Research Progress on the Biological Function and Homeostatic Disruption of Microglia in the Pathogenesis of Major Depressive Disorder
    Shuqi Kong, Zhuoyue Huang, Yiru Fang · 2026 · Neuroscience Bulletin
77. Novel Therapeutic Targets for Major Depressive Disorder
    Max A. Lazar, Roger S. McIntyre · 2019 · Elsevier eBooks
78. Relationship between the double burden of malnutrition and mental health in overweight and obese adult women
    Mohammad Gholizadeh, Leila Setayesh, Habib Yarizadeh, Atieh Mirzababaei, Cain C. T. Clark, Khadijeh Mirzaei · 2022 · Journal of Nutritional Science
79. Vicarious defeat stress induces increased alcohol consumption in female mice: Role of neurokinin‐1 receptor and interleukin‐6
    Ellie B. Decker Ramirez, Miranda E. Arnold, Jesse R. Schank · 2023 · Addiction Biology
80. Alcohol Enhances Responses to High Frequency Stimulation in Hippocampus from Transgenic Mice with Increased Astrocyte Expression of IL-6
    Donna L. Gruol, Ruben V. Hernandez, Amanda J. Roberts · 2020 · Cellular and Molecular Neurobiology
81. Depression as a risk factor for Alzheimer’s disease: A human post-mortem study
    Mizuki Morisaki, Farnoosh Rezaali, Laurie C. Lau, Delphine Boche, Golam Mohammed Khandaker, Gustavo Turecki, Lindsey Isla Sinclair · 2025 · PLoS ONE
82. Anti‐depression molecular mechanism elucidation of the phytochemicals in edible flower of Hemerocallis citrina Baroni
    Ruohan Zhao, Jinhai Luo, Sookja Kim Chung, Baojun Xu · 2024 · Food Science & Nutrition
83. Rodent Models of Stress-Induced Depression: The Link Between Stress and Immune System Related Changes
    B. W. McGuinness, Andrew Harkin · 2015 · Current topics in neurotoxicity
84. Interleukin-6 in epilepsy and its neuropsychiatric comorbidities: How to bridge the gap
    Xiao-Man Chen, Shuo Zhang, Shiqi Gao, Michael Y. Xu · 2024 · World Journal of Psychiatry
85. Sex differences in inflammatory mechanisms related to alcohol use disorder and depression
    Ellie B Decker Ramirez, Jesse R. Schank · 2025 · Brain Behavior and Immunity
86. Lessons From Clinical Trials of Immunomodulatory Drugs in Psychiatric Disorders
    Thomas Kun Pak, Nabila Haque, Manish K. Jha · 2025 · Biological Psychiatry
87. A real-world pharmacovigilance study of FDA adverse event reporting system (FAERS) events for bimekizumab
    Zhuomiao Lin, Xihui Yu, Meiqing Yang, Jialan Xu, Jiahong Zhong · 2026 · Frontiers in Pharmacology
88. Inflammatory Cytokines as a Shared Pathophysiological Pathway in Depression and Chronic Insomnia: A Narrative Review of Mechanisms and Clinical Implications
    Ning Ren, XiaoNa Zhang, Zhe Yu, Yangfei Che, Yajie Zhang, Mingfen Song, Hongjing Mao · 2026 · Neuropsychiatric Disease and Treatment
89. Neural Mechanism of Exercise: Neurovascular Responses to Exercise
    Ti‐Fei Yuan, Nuno Rocha, Flávia Paes, Óscar Arias-Carrión, Sergio Eduardo de Carvalho Machado, Alberto Souza Sá Filho · 2015 · CNS & Neurological Disorders - Drug Targets
90. Personality traits as a possible factor in the inflammatory response in the first depression episode and in recurrent depressive disorders
    Monika Ewa Talarowska, Katarzyna Maria Bliźniewska-Kowalska, Janusz Szemraj, M. Kowalczyk, Piotr Gałecki · 2018 · The European Journal of Psychiatry
91. Protein Cytokines, Cytokine Gene Polymorphisms, and Potential Acute Coronary Syndrome Symptoms
    Sahereh Mirzaei, Larisa Burke, Anne G. Rosenfeld, Susan L. Dunn, Jennifer R. Dungan, Katherine A. Maki, Holli A. DeVon · 2019 · Biological Research For Nursing
92. Is Riparin III a promising drug in the treatment for depression?
    Auriana Serra Vasconcelos Mallmann, Raquell de Castro Chaves, Natália Ferreira de Oliveira, Iris Cristina Maia Oliveira, Victor Celso Cavalcanti Capibaribe, José Tiago Valentim, Daniel Moreira Alves da Silva, Danusio Pinheiro Sartori, Gabriel Carvalho Rodrigues, Adriano José Maia Chaves Filho et al. · 2021 · European Journal of Pharmaceutical Sciences
93. Common mechanisms involved in lung cancer and depression: The dominant role of interleukin-6-IDO pathway in the lung-brain axis
    Haiting Tang, Yongping Zhang, Shuai Zhao, Cai Song · 2023 · Journal of Affective Disorders Reports
94. Major depressive disorder (mdd): emerging immune targets at preclinical level
    Manasi Varma, Arshpreet Kaur, Ranjana Bhandari, Ashwani Kumar, Anurag Kuhad · 2023 · Expert Opinion on Therapeutic Targets
95. Construction of gene-classifier and co-expression network analysis of genes in association with major depressive disorder
    Dongmei Guo, Shumin Zhang, Zhen Tang, Hanyan Wang · 2020 · Psychiatry Research
96. Rigid linker peptides improve the stability and anti‐inflammation effect of human serum albumin and α‐melanocyte‐stimulating hormone fusion proteins
    Yiyao Liu, Yang Li, Xueyan Wei, Inam Ullah, Shahab Uddin M.S., Jiatao Wang, Runjie Xia, Meizhu Wang, Hui Yang, Hongyu Li · 2024 · Biotechnology Journal
97. Revealing genetic causality between blood-based biomarkers and major depression in east Asian ancestry
    Xiaoxiao Mo, Chao Wang, Qiuyi Pu, Zhengdong D. Zhang, Dong‐Mei Wu · 2024 · Frontiers in Psychiatry
98. Giant Cell Arteritis Presenting as Depressed Mood and Headache in an Elderly Patient
    Bharat Kumar, Dale E. Toney, Mujahed Alikhan, Kristine M. Lohr · 2013 · JCR Journal of Clinical Rheumatology
99. Cyclosomatostatin-induced catalepsy in aged rats: Specific change of brain c-Fos protein expression in the lateral entorhinal cortex
    Ilya D. Ionov, Irina I. Pushinskaya, Nicholas P. Gorev, David D. Frenkel · 2020 · Brain Research Bulletin
100. The effects of social defeat stress on hippocampal glial cells and interleukin-6 in adolescence and adulthood
     Yingjuan Xu, Jiling Zhang, Zeman Fang, Handi Zhang · 2022 · Neuroreport