Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes

Sukoff Rizzo, S J, Neal, S J, Hughes, Z A, Beyna, M, Rosenzweig-Lipson, S, Moss, S J, Brandon, N J·2012·Translational Psychiatry

Cited by (240)

Items 201–240 of 240

  1. Protective effect of salicylic acid on Hg 0 intoxication in mice
    Chunyan Ma, Di Xie, Linli Huang, Lihong Sun, Qiang Xu, Guangzhe Li, Lin Hao · 2013 · Inhalation Toxicology
  2. Exogenous L-fucose attenuates depression induced by chronic unpredictable stress: Implicating core fucosylation has an antidepressant potential
    Dan Wang, Tomohiko Fukuda, Tian-Gui Wu, Xing Xu, T. Isaji, Jianguo Gu · 2025 · Journal of Biological Chemistry
  3. Inflammation in treatment-resistant depression: From mechanisms to therapeutics
    Shijin Wu, Xiaofa Gao, Yuyang Zhou, Zibo Lin, C H Chen, Jing Luo, Xiaoyun Liu, Liming Lin, 邵红伟, Song Liu · 2026 · Brain Research Bulletin
  4. Associations between serum estradiol and IL-6/sIL-6R/sgp130 complex in female patients with major depressive disorder
    Ting Sun, Qian Chen, Junchi Mei, Yan Li · 2023 · BMC Psychiatry
  5. Дискуссионные аспекты суицидологии: связь нейровоспаления с суицидальным поведением у психически здоровых людей. Сообщение I
    Vadim A. Kozlov, А.В. Голенков, Pavel B. Zotov, Булыгина Ирина Евгеньевна · 2024 · Суицидология
  6. A study of the effects of chronic neuroinflammation on cognition and behaviour in the GFAP-IL6 transgenic mouse and investigation of the flavonoid apigenin as a neuroprotective agent
    Sandra Sonego · 2018
  7. α7 Nicotinic acetylcholine receptor-mediated anti-inflammatory actions modulate brain functions
    2016 · Neurotransmitter
  8. Causas biológicas de depressão em doentes com lupus eritematoso sistémico: um estudo de revisão
    Joana Carvalho Figueiredo Ferreira Braga · 2014 · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
  9. Dietary inflammatory potential and depression in middle-aged and older adults: A population-based study of associations and comorbid disease network
    Yucheng Yang, Junhan Zhang, Xiaona Na, Yuefeng Tan, Chuhan Wu, X.Q. Shi, Ai Zhao · 2025 · Journal of Affective Disorders
  10. Chaihu Shugan San exerts antidepressant effects in female mice by suppressing hippocampal IL-6 and activating the cAMP-CaMKII-BDNF pathway
    Xiangfei Liu, Banxin Luo, Li Gao, Lida Zhang, Xiao Li, Qiuling Lu, Junru Zhang, Junji Zhu, Jiacheng Qian, Chenxiao Shan et al. · 2026 · Journal of Ethnopharmacology
  11. Diminished responses to monoaminergic antidepressants but not ketamine in a mouse model for neuropsychiatric lupus
    Bettadapura N. Srikumar, Pattipati S. Naidu, Narasimharaju Kalidindi, M. S. Paschapur, Bharath Adepu, Siva Subramani, Jignesh Nagar, Ratika Srivastava, Muppana V. Sreedhara, Durga Shiva Prasad et al. · 2018 · Journal of Psychopharmacology
  12. The Cytokine Interleukin 6 (IL-6) as a Neural and Endocrine Regulator
    K. Nava-Castro, L. A. Méndez-García, H. Solleiro-Villavicencio, J. Morales-Montor · 2020 · Advances in Neuroimmune Biology
  13. Pathogenesis of Neuropsychiatric Lupus
    Ariel D. Stock, Ayal Ben‐Zvi, Chaim Putterman · 2019 · Elsevier eBooks
  14. Different Effects of Fluoxetine and Paroxetine Combined with Vitamin D3 in Ovariectomized Rats Exposed to Unpredictable Stress
    Julia Fedotova · 2020 · The Open Biology Journal
  15. Linking interleukin-6 and depression
    Manivel L. Rengasamy, Rebecca B. Price · 2021 · Elsevier eBooks
  16. Evidence to support peripheral and central IL-6 signaling targets to treat depression
    Trehani M. Fonseka, Roger S. McIntyre, Joanna K. Soczynska, Sidney H. Kennedy · 2015 · Expert Opinion on Investigational Drugs
  17. Role of Interferon-Gamma and Leucine-Rich Repeat Kinase 2 in Stress-Related Pathology
    Darcy Litteljohn · 2016
  18. Nicotine for Psychiatric Disease: From Nuisance to Novel Treatment?
    Marco Atzori, Manuel Mejía · 2015 · Future Medicinal Chemistry
  19. Roles of dopaminergic systems and inflammation-related molecules derived from microglia in stress-induced behavioral changes
    Ryota Shinohara, Shiho Kitaoka, Tomoyuki Furuyashiki · 2016 · PAIN RESEARCH
  20. Mediators of neuroinflammation
    Rajiv Tikamdas, Ping Zhang, Bin Liu · 2016
  21. Article Open Access
    Holly Lawford‐Smith · 2015
  22. Beliefs about the Impact of Excess Body Weight on Biopsychosocial Functioning in Multiple Sclerosis Patients
    Abigail R. Ness · 2017 · MOspace Institutional Repository (University of Missouri)
  23. The two sides of the coin of psychosocial stress: evaluation by positron emission tomography
    Paula Kopschina Feltes · 2018 · University of Groningen research database (University of Groningen / Centre for Information Technology)
  24. Inflammation and accumulating risk for developing psychiatric disorders
    Kelli M. Money · 2016
  25. Avaliação dos efeitos do canabidiol sobre as alterações neuroimunoendócrinas e comportamentais induzidas pelo estresse em camundongos
    Alice Hartmann dos Santos · 2020 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
  26. The Relationship between Double Burden of Malnutrition and Mental Health among Adult Females
    Mohammad Gholizadeh, Leila Setayesh, Habib Yarizadeh, Atieh Mirzababaei, Khadijeh Mirzaei · 2021 · Research Square
  27. The Impact of SSRI Use on the Clinical Outcome and Prognosis of COVID-19 Patients: A Single-Center Prospective Study
    Mitra Safa, Seyed Ali Ziaee, Afshin Moniri, Fatemeh Ghassem Boroujerdi, Farzaneh Haji Zadeh, Amirali Soheili, Siamak Afaghi, Fatemeh Sadat Rahimi, Bamdad Mirab Zadeh Ardekani · 2022 · Current Psychopharmacologye
  28. Ethanol extract of Alpiniae oxyphyllae fructus regulates glucose metabolism, the HPA axis and hippocampal function in diabetic mice with depression
    Qilun Zhou, Yue Qi, Jinlan Deng, Ruonan Li, Yongping Zhang, Xiaofeng Zhang · 2023 · Research Square
  29. Avaliação longitudinal de neurometabólitos na substância branca e sua associação com manifestações neuropsiquiátricas e citocinas Th1 e Th2 em pacientes com lúpus eritematoso sistêmico
    Renan Bazuco Frittoli · 2021
  30. Pathogenesis of neuropsychiatric lupus
    Erica Moore, Ayal Ben‐Zvi, Chaim Putterman · 2024 · Elsevier eBooks
  31. Whole-body hyperthermia as a novel antidepressant therapy
    Kevin D. Gaitonde, Henry A. Nasrallah · 2025 · Biomarkers in Neuropsychiatry
  32. Correlation between serum inflammatory factors and psychosomatic syndrome in patients with chronic obstructive pulmonary disease: an observational study
    Wenjing Zhang, Yujuan Cui, Ling V. Sun, Chunlin Tu, Yanfang Yu · 2025 · Frontiers in Psychiatry
  33. Potentialisation de la réponse antidépressive par la lumière : étude préclinique
    Sarah Delcourte · 2019 · theses.fr (ABES)
  34. Rôle de la neurogenèse hippocampique adulte dans la résilience au stress : étude dans deux modèles murins de stress aigu et chronique
    Barbara Planchez · 2021 · theses.fr (ABES)
  35. Rôles directs d'une chimiothérapie et vésicules libérées par le cancer sur les déficits cognitifs et/ou émotionnels dans des modèles précliniques
    Renaud Parment · 2023 · theses.fr (ABES)
  36. Insights into the blood–brain barrier in mental health disorders: from experimental models to clinical findings
    Maria Grazia Ferraro, Adrien Stanley, Pellegrino Lippiello, Silvia Pascarella, Luisa Speranza, Mariateresa Ricci, Floriana Volpicelli, Sergio Chieffi, Maria Concetta Miniaci · 2026 · Reviews in the Neurosciences
  37. Environmental enrichment alleviates chronic unpredictable stress-induced cognitive dysfunction in male rats and is associated with alterations in BDNF/TrkB signaling
    Ece Durmuş Gündoğdu, Hale SAYAN ÖZAÇMAK · 2026 · Brain Research
  38. Neurobiological and Neuroimmune Mechanisms Linking Chronic Pain, Sleep Disturbances and Mental Health Disorders
    Boris Burnjaković, Harrison Moy, Aleksandar Sič, Nebojša Nick Knežević · 2026 · International Journal of Molecular Sciences
  39. Effects of Early Proinflammatory Stress and Increased Crowding in Adulthood on Social Behavior and the Expression of Neuroinflammation-Associated Genes in Rats
    I. V. Pavlova, N. D. Broshevitskaya · 2026 · Journal of Evolutionary Biochemistry and Physiology
  40. Stoichiometric insufficiency of the IL-6 sgp130 trans-signaling buffer in treatment-resistant depression
    Franco Giordano Sanchez García, Saúl Ramirez de los Santos, Vito S. Hernández, Fernando Jáuregui Huerta · 2026 · Personalized Medicine in Psychiatry