The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
Anti-staphylococcal plant natural products
Abstract
Covering: 1995 to 2003 The occurrence of vancomycin-resistant Staphylococcus aureus (VRSA) and multidrug-resistant (MDR) strains of this organism necessitate the discovery of new classes of anti-staphylococcal drug leads. At present there are no single chemical entity plant derived antibacterials used clinically, and this biologically diverse group deserves consideration as a source of chemical diversity for two important reasons. Firstly, plants have exceptional ability to produce cytotoxic agents and, secondly, there is an ecological rationale that antibacterial natural products should be present or synthesised de novo following microbial attack to protect plants from invasive and pathogenic microbes in their environment. This review cites plant natural products that either modify resistance in Staphylococcus aureus or are antibacterial through bacteriostatic or bactericidal properties. The activities described here show that there are many potential new classes of anti-staphylococcal agents which should undergo further cytotoxicity, microbial specificity and preclinical in vivo studies to assess their potential.
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Cites
Linezolid resistance in a clinical isolate of Staphylococcus aureus
Tsiodras, S., Gold, H. S., Sakoulas, G., Eliopoulos, G. M., Wennersten, C., Venkataraman, L., Moellering, R. C., & Ferraro, M. J. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05410-1 · Cited by 1,033
Antimicrobial activity of the major components of the essential oil of Melaleuca alternifolia
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Multidrug Pump Inhibitors Uncover Remarkable Activity of Plant Antimicrobials
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Interactions between components of the essential oil of Melaleuca alternifolia
Cox, S. D., Mann, C. M., & Markham, J. L. (2001) · Journal of Applied Microbiology · doi:10.1046/j.1365-2672.2001.01406.x · Cited by 301
A comparative study of tea‐tree oil versus benzoylperoxide in the treatment of acne
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TSAO, S.-M., & YIN, M.-C. (2001) · Journal of Medical Microbiology · doi:10.1099/0022-1317-50-7-646 · Cited by 219
Multiple Novel Inhibitors of the NorA Multidrug Transporter of Staphylococcus aureus
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A novel inhibitor of multidrug efflux pumps in Staphylococcus aureus
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Self-citationGibbons, S., & Udo, E. E. (2000) · Phytotherapy Research · doi:10.1002/(sici)1099-1573(200003)14:2<139::aid-ptr608>3.0.co;2-8 · Cited by 207
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Cited by
Platforms for antibiotic discovery
Lewis, K. (2013) · Nature Reviews Drug Discovery · doi:10.1038/nrd3975 · Cited by 1,445
Interaction between Phenolics and Gut Microbiota: Role in Human Health
Selma, M. V., Espín, J. C., & Tomás-Barberán, F. A. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf902107d · Cited by 1,324
Antibacterial Cannabinoids from Cannabis sativa: A Structure−Activity Study
Appendino, G., Gibbons, S., Giana, A., Pagani, A., Grassi, G., Stavri, M., Smith, E., & Rahman, M. M. (2008) · Journal of Natural Products · doi:10.1021/np8002673 · Cited by 661
Self-citationPlant-derived compounds in clinical trials
Saklani, A., & Kutty, S. K. (2008) · Drug Discovery Today · doi:10.1016/j.drudis.2007.10.010 · Cited by 477
Simões, M., Bennett, R. N., & Rosa, E. A. S. (2009) · Natural Product Reports · doi:10.1039/b821648g · Cited by 444
Metadata
- Authors
- Gibbons, S.
- Venue
- Natural Product Reports
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2004
- Volume
- 21
- Issue
- 2
- Pages
- 263
- ISSN
- 0265-0568 (ISSN-L)
- 1460-4752
- OpenAlex
- W2135986898
- Cited by
- 531
- References
- 52
- FWCI
- 10.76
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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