The DOI matches its Crossref record; 90 of the 90 references it cites were found in a registry or an index.
Injectable scaffolds for tissue regeneration
Abstract
Tissue engineering aims to develop functional substitutes for damaged or diseased tissues through complex constructs of living cells, bioactive molecules and three-dimensional porous scaffolds, which support cell attachment, proliferation and differentiation. Such constructs can be formed either by seeding cells within a pre-formed scaffold or through injection of a solidifiable precursor and cell mixture to the defective tissue. As cell and bioactive molecule carriers, injectable scaffolds are appealing, particularly from the clinical point of view, because they offer the possibility of homogeneously distributing cells and molecular signals throughout the scaffold and can be injected directly into cavities, even of irregular shape and size, in a minimally invasive manner. In this paper the challenges in designing an injectable scaffold from the viewpoint of materials chemistry and the solidification mechanisms of injectable precursors are discussed. The applications of injectable scaffolds in angiogenesis, bone repair and cartilage regeneration are described.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Hydrogels for Tissue Engineering
Lee, K. Y., & Mooney, D. J. (2001) · Chemical Reviews · doi:10.1021/cr000108x · Cited by 5,277
Alginate hydrogels as synthetic extracellular matrix materials
Rowley, J. A., Madlambayan, G., & Mooney, D. J. (1999) · Biomaterials · doi:10.1016/s0142-9612(98)00107-0 · Cited by 2,342
Biodegradable block copolymers as injectable drug-delivery systems
Jeong, B., Bae, Y. H., Lee, D. S., & Kim, S. W. (1997) · Nature · doi:10.1038/42218 · Cited by 1,997
Novel crosslinking methods to design hydrogels
Hennink, W. E., & van Nostrum, C. F. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00240-x · Cited by 1,962
Photopolymerizable hydrogels for tissue engineering applications
Nguyen, K. T., & West, J. L. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00175-8 · Cited by 1,669
Kuo, C. K., & Ma, P. X. (2001) · Biomaterials · doi:10.1016/s0142-9612(00)00201-5 · Cited by 1,491
Novel injectable neutral solutions of chitosan form biodegradable gels in situ
Chenite, A., Chaput, C., Wang, D., Combes, C., Buschmann, M. D., Hoemann, C. D., Leroux, J. C., Atkinson, B. L., Binette, F., & Selmani, A. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00116-2 · Cited by 1,406
Burdick, J. A., & Anseth, K. S. (2002) · Biomaterials · doi:10.1016/s0142-9612(02)00176-x · Cited by 1,008
Sawhney, A. S., Pathak, C. P., & Hubbell, J. A. (1993) · Macromolecules · doi:10.1021/ma00056a005 · Cited by 974
Incorporation of adhesion peptides into nonadhesive hydrogels useful for tissue resurfacing
Hern, D. L., & Hubbell, J. A. (1998) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(199802)39:2<266::aid-jbm14>3.0.co;2-b · Cited by 904
Cited by
Alginate-Based Biomaterials for Regenerative Medicine Applications
Sun, J., & Tan, H. (2013) · Materials · doi:10.3390/ma6041285 · Cited by 1,361
Injectable, Biodegradable Hydrogels for Tissue Engineering Applications
Tan, H., & Marra, K. G. (2010) · Materials · doi:10.3390/ma3031746 · Cited by 639
Injectable matrices and scaffolds for drug delivery in tissue engineering
Kretlow, J. D., Klouda, L., & Mikos, A. G. (2007) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2007.03.013 · Cited by 629
Qu, J., Zhao, X., Ma, P. X., & Guo, B. (2017) · Acta Biomaterialia · doi:10.1016/j.actbio.2017.06.001 · Cited by 593
Recent Advances in Design of Functional Biocompatible Hydrogels for Bone Tissue Engineering
Xue, X., Hu, Y., Deng, Y., & Su, J. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202009432 · Cited by 532
Metadata
- Authors
- Hou, Q., De Bank, P. A., & Shakesheff, K. M.
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2004
- Volume
- 14
- Issue
- 13
- Pages
- 1915
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2116863259
- Cited by
- 301
- References
- 90
- FWCI
- 5.30
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Injectable scaffolds for tissue regeneration. https://app.cochat.ai/papers/10.1039/b401791a
- The paper
- Hou, Q., De Bank, P. A., & Shakesheff, K. M. (2004). Injectable scaffolds for tissue regeneration. Journal of Materials Chemistry. https://doi.org/10.1039/b401791a
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
