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Fluorescent core–shell silica nanoparticles: towards “Lab on a Particle” architectures for nanobiotechnology
Abstract
Novel nanoscale fluorescent materials are integral to the progress of emergent fields such as nanobiotechnology and facilitate new research in a variety of contexts. Sol-gel derived silica is an excellent host material for creating fluorescent nanoparticles by the inclusion of covalently-bound organic dyes. Significant enhancements in the brightness and stability of organic dye emission can be achieved for silica-based core-shell nanoparticle architectures at length scales down to tens of nanometers with narrow size distributions. This tutorial review will highlight these findings and describe the evolution of the fluorescent core-shell silica nanoparticle concept towards integration of multiple functionalities including mesoporosity, metal nanoshells and quantitative chemical sensing. These developments point towards the development of "lab on a particle" architectures with promising prospects for nanobiotechnology, drug development and beyond.
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Carmeliet, P., & Jain, R. K. (2000) · Nature · doi:10.1038/35025220 · Cited by 9,070
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Wang, Y., Zhao, Q., Han, N., Bai, L., Li, J., Liu, J., Che, E., Hu, L., Zhang, Q., Jiang, T., et al. (2015) · Nanomedicine: Nanotechnology, Biology and Medicine · doi:10.1016/j.nano.2014.09.014 · Cited by 1,192
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Metadata
- Authors
- Burns, A., Ow, H., & Wiesner, U.
- Venue
- Chem. Soc. Rev.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2006
- Volume
- 35
- Issue
- 11
- Pages
- 1028-1042
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2109464992
- Cited by
- 849
- References
- 1
- FWCI
- 2.66
- Type
- journal article
- Language
- en
- Open access
- closed
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- Burns, A., Ow, H., & Wiesner, U. (2006). Fluorescent core–shell silica nanoparticles: towards “Lab on a Particle” architectures for nanobiotechnology. Chem. Soc. Rev. https://doi.org/10.1039/b600562b
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