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Synthetic ion channels in bilayer membranes
Abstract
Natural ion channels are large protein complexes that regulate key functions of cells. Supramolecular chemists have been able to take hints from Nature to design and prepare completely synthetic ion channel systems that reproduce many of the fundamental functions of natural channels. This tutorial review introduces the field to non-specialists. It examines the design, synthesis, incorporation, and characterization of synthetic ion channels in bilayer membranes, and points to potential applications of synthetic ion channels.
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Cited by
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Davis, J. T., Okunola, O., & Quesada, R. (2010) · Chemical Society Reviews · doi:10.1039/b926164h · Cited by 372
Chiral Selective Transmembrane Transport of Amino Acids through Artificial Channels
Chen, L., Si, W., Zhang, L., Tang, G., Li, Z.-T., & Hou, J.-L. (2013) · Journal of the American Chemical Society · doi:10.1021/ja312704e · Cited by 305
Systems protobiology: origin of life in lipid catalytic networks
Lancet, D., Zidovetzki, R., & Markovitch, O. (2018) · Journal of The Royal Society Interface · doi:10.1098/rsif.2018.0159 · Cited by 182
Calixarenes: from biomimetic receptors to multivalent ligands for biomolecular recognition
Sansone, F., Baldini, L., Casnati, A., & Ungaro, R. (2010) · New Journal of Chemistry · doi:10.1039/c0nj00285b · Cited by 167
Metadata
- Authors
- Fyles, T. M.
- Venue
- Chem. Soc. Rev.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2007
- Volume
- 36
- Issue
- 2
- Pages
- 335-347
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2340178576
- Cited by
- 336
- References
- 0
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- closed
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