The DOI matches its Crossref record; 19 of the 19 references it cites were found in a registry or an index.
Determining accurate molecular sizes in solution through NMR diffusion spectroscopy
Abstract
This tutorial review deals with the methodological procedures that can be used to obtain accurate molecular sizes in solution from diffusion NMR spectroscopy. The critical aspects associated with the estimation of the size of molecules from the measured translational self-diffusion coefficient, using the Stokes-Einstein equation, are highlighted and discussed. From a theoretical point of view, it is shown how to take into account the size of the solute with respect to that of the solvent and its non-spherical shape using the appropriate correction factors in the frictional coefficient. From a practical point of view, the advantages of introducing an internal standard in the sample are presented. Initially, non-aggregating systems are considered in an attempt to clarify what hydrodynamic dimensions mean. Successively, aggregating systems are addressed showing how it is possible to understand the aggregation level and derive the thermodynamic parameters for some illustrative aggregation processes.
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Cites
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Koller, R., Stanek, K., Stolz, D., Aardoom, R., Niedermann, K., & Togni, A. (2009) · Angewandte Chemie International Edition · doi:10.1002/anie.200900974 · Cited by 313
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Metadata
- Authors
- Macchioni, A., Ciancaleoni, G., Zuccaccia, C., & Zuccaccia, D.
- Venue
- Chem. Soc. Rev.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2008
- Volume
- 37
- Issue
- 3
- Pages
- 479-489
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2005692644
- Cited by
- 591
- References
- 19
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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