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Supramolecular hydrogels based on biofunctional nanofibers of self-assembled small molecules
Abstract
This Feature Article summarizes the design and synthesis of supramolecular hydrogels based on nanofibers of self-assembled small bioactive molecules. The hydrogels show responses to molecular recognition and find applications in wound healing, toxin removal, and drug release. We also described our recent results of using an enzyme or enzymatic switch to trigger or regulate the self-assembly of small molecules for the generation of nanofibers and the subsequent hydrogelation. The results in this Feature Article clearly indicate that supramolecular hydrogels, as an expression of the self-assembly of molecules in water, promise a broad range of biomaterials and therapeutics.
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Citations
Cited by
Advances in engineering hydrogels
Zhang, Y. S., & Khademhosseini, A. (2017) · Science · doi:10.1126/science.aaf3627 · Cited by 2,908
Tao, K., Levin, A., Adler-Abramovich, L., & Gazit, E. (2016) · Chemical Society Reviews · doi:10.1039/c5cs00889a · Cited by 482
Self-assembling materials for therapeutic delivery
Branco, M. C., & Schneider, J. P. (2009) · Acta Biomaterialia · doi:10.1016/j.actbio.2008.09.018 · Cited by 462
Applications of electrospun nanofibers
Fang, J., Niu, H., Lin, T., & Wang, X. (2008) · Science Bulletin · doi:10.1007/s11434-008-0319-0 · Cited by 313
Supramolecular Hydrogel Exhibiting Four Basic Logic Gate Functions To Fine-Tune Substance Release
Komatsu, H., Matsumoto, S., Tamaru, S.-I., Kaneko, K., Ikeda, M., & Hamachi, I. (2009) · Journal of the American Chemical Society · doi:10.1021/ja8098239 · Cited by 305
Metadata
- Authors
- Yang, Z., & Xu, B.
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2007
- Volume
- 17
- Issue
- 23
- Pages
- 2385
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2093641424
- Cited by
- 185
- References
- 0
- FWCI
- 8.19
- Type
- journal article
- Language
- en
- Open access
- closed
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- Yang, Z., & Xu, B. (2007). Supramolecular hydrogels based on biofunctional nanofibers of self-assembled small molecules. Journal of Materials Chemistry. https://doi.org/10.1039/b702493b
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
