The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.
Self-assembling materials for therapeutic delivery
Open accessAbstract
A growing number of medications must be administered through parenteral delivery, i.e., intravenous, intramuscular, or subcutaneous injection, to ensure effectiveness of the therapeutic. For some therapeutics, the use of delivery vehicles in conjunction with this delivery mechanism can improve drug efficacy and patient compliance. Macromolecular self-assembly has been exploited recently to engineer materials for the encapsulation and controlled delivery of therapeutics. Self-assembled materials offer the advantages of conventional crosslinked materials normally used for release, but also provide the ability to tailor specific bulk material properties, such as release profiles, at the molecular level via monomer design. As a result, the design of materials from the “bottom up” approach has generated a variety of supramolecular devices for biomedical applications. This review provides an overview of self-assembling molecules, their resultant structures, and their use in therapeutic delivery. It highlights the current progress in the design of polymer- and peptide-based self-assembled materials.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
2 retracted
Hosseinkhani, H., Hosseinkhani, M., Khademhosseini, A., & Kobayashi, H. (2007) · Journal of Controlled Release · doi:10.1016/j.jconrel.2006.11.018 · Cited by 163
RetractedElsabahy, M., Perron, M.-È., Bertrand, N., Yu, G.-E., & Leroux, J.-C. (2007) · Biomacromolecules · doi:10.1021/bm070226v · Cited by 83
RetractedWhitesides, G. M., & Grzybowski, B. (2002) · Science · doi:10.1126/science.1070821 · Cited by 7,439
Recent advances with liposomes as pharmaceutical carriers
Torchilin, V. P. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1632 · Cited by 5,282
Hydrogels in Biology and Medicine: From Molecular Principles to Bionanotechnology
Peppas, N. A., Hilt, J. Z., Khademhosseini, A., & Langer, R. (2006) · Advanced Materials · doi:10.1002/adma.200501612 · Cited by 4,109
Hydrogels in pharmaceutical formulations
Peppas, N. (2000) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/s0939-6411(00)00090-4 · Cited by 4,011
Designing materials for biology and medicine
Langer, R., & Tirrell, D. A. (2004) · Nature · doi:10.1038/nature02388 · Cited by 3,198
Design and development of polymers for gene delivery
Pack, D. W., Hoffman, A. S., Pun, S., & Stayton, P. S. (2005) · Nature Reviews Drug Discovery · doi:10.1038/nrd1775 · Cited by 2,568
Polymersomes: Tough Vesicles Made from Diblock Copolymers
Discher, B. M., Won, Y.-Y., Ege, D. S., Lee, J. C.-M., Bates, F. S., Discher, D. E., & Hammer, D. A. (1999) · Science · doi:10.1126/science.284.5417.1143 · Cited by 2,512
Selective Differentiation of Neural Progenitor Cells by High-Epitope Density Nanofibers
Silva, G. A., Czeisler, C., Niece, K. L., Beniash, E., Harrington, D. A., Kessler, J. A., & Stupp, S. I. (2004) · Science · doi:10.1126/science.1093783 · Cited by 2,169
Cited by
Molecular self-assembly and applications of designer peptide amphiphiles
Zhao, X., Pan, F., Xu, H., Yaseen, M., Shan, H., Hauser, C. A. E., Zhang, S., & Lu, J. R. (2010) · Chemical Society Reviews · doi:10.1039/b915923c · Cited by 668
Tannic acid-based sustained-release system for protein drugs
Utatsu, K., Motoyama, K., Nakamura, T., Onodera, R., & Higashi, T. (2023) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.123229 · Cited by 31
Metadata
- Authors
- Branco, M. C., & Schneider, J. P.
- Venue
- Acta Biomaterialia
- Publisher
- Elsevier BV
- Published
- 2009-03
- Volume
- 5
- Issue
- 3
- Pages
- 817-831
- ISSN
- 1742-7061 (ISSN-L)
- OpenAlex
- W2009881105
- Cited by
- 462
- References
- 144
- FWCI
- 13.42
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Self-assembling materials for therapeutic delivery. https://app.cochat.ai/papers/10.1016/j.actbio.2008.09.018
- The paper
- Branco, M. C., & Schneider, J. P. (2009). Self-assembling materials for therapeutic delivery. Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2008.09.018
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
