Entropically-driven ring-opening polymerization of macrocyclic esters with up to 84-membered rings catalysed by polymer-supported Candida antarctica lipase B
Abstract
Macrocyclic esters with 24- to 84-ring atoms can be polymerized successfully using PS Candida antarctica lipase B as the catalyst. This method allows the polymerization of macrocycles containing substantial in-chain functional moieties, such as monomers incorporating steroid residues. It also affords metal-free products.
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Gains in rotational and vibrational degrees of freedom can lead to positive changes in ΔS_p° but are only rarely large enough to fully offset the large decrease in translational entropy that usually accompanies polymerization.
“Gains in rotational and vibrational degrees of freedom can lead to positive changes in Δ S p ° but are only rarely large enough to fully o ff set the large decrease in translational entropy that usually accompanies polymerization. 71,72”
From Aliphatic Polyester Block Polymer Design (2016) · cites this paper as [71]
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- Authors
- Manzini, B., Hodge, P., & Ben-Haida, A.
- Affiliations
- University of Manchester (GB)
- Corresponding author
- Hodge, Philip
- ORCID
- Hodge, Philip
- Venue
- Polym. Chem.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 1
- Issue
- 3
- Pages
- 339-346
- ISSN
- 1759-9954 (ISSN-L)
- 1759-9962
- OpenAlex
- W2017892995
- Cited by
- 28
- References
- 35
- Citations by year
- 2023: 1 · 2022: 2 · 2021: 4 · 2019: 2 · 2017: 3 · 2016: 5 · 2015: 3 · 2014: 2 · 2013: 1 · 2012: 2
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Polymer Chemistry (publishedVersion)
- Funders
- Engineering and Physical Sciences Research Council
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Enzyme Catalysis and Immobilization
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
- Keywords
- ring-opening polymerization, Candida antarctica lipase B, entropic driving force, enzymatic polymerization
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