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Cited by 417

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Immobilization of bio-macromolecules on self-assembled monolayers: methods and sensor applications

Samanta, Debasis, Sarkar, Amitabha·2011·Chemical Society Reviews

Abstract

Attachment of biomolecules on gold, silicon or glass surfaces has direct implications for the development of novel biosensors in the context of nanoscale detection of pathogens and other metabolites related to issues of human health. In this critical review, we have highlighted the current developments in various techniques of immobilization of biomolecules, specifically biological macromolecules on surfaces through the modification of a functional self-assembled monolayer. The utility of such immobilized biomolecules in the area of biosensing in nanoscale has been surveyed. Merits and demerits of some of the methods with reference to sensitivity of detection and practical use have been discussed (221 references).

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Metadata

Authors
Samanta, D., & Sarkar, A.
Venue
Chemical Society Reviews
Published
2011
Volume
40
Issue
5
Pages
2567
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
OpenAlex
W2020820266
Cited by
417
References
1
FWCI
2.77
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Immobilization of bio-macromolecules on self-assembled monolayers: methods and sensor applications. https://app.cochat.ai/papers/10.1039/c0cs00056f
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Samanta, D., & Sarkar, A. (2011). Immobilization of bio-macromolecules on self-assembled monolayers: methods and sensor applications. Chemical Society Reviews. https://doi.org/10.1039/c0cs00056f

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