The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Prussian blue modified iron oxide magnetic nanoparticles and their high peroxidase-like activity
Abstract
Prussian blue (PB) modified γ-Fe2O3 magnetic nanoparticles (MNPs) featuring varying PB proportions were synthesized and characterized by TEM, FTIR, UV-vis, EDS, XRD and XPS. The magnetic properties and peroxidase-like catalytic activity of the synthesized nanoparticles were investigated. With increasing PB content, the magnetism could still maintain a high level. Peroxidase-like activity was enhanced as the PB proportion increased. Catalysis was found to follow Michaelis–Menten kinetics. The calculated kinetic parameters exhibited strong affinity with substrates and high catalytic activity, which are three orders of magnitudes larger than that for magnetite nanoparticles of similar size. Based on the high activity, an enzyme immunoassay model was established: staphylococcal protein A (SPA) was conjugated onto the surface of the nanoparticles to construct a new nanoprobe which was employed to detect IgG immobilized to 96-well plates. The results presented a linear absorbance enhancement with concentration of IgG, suggesting that PBMNPs serve as an inexpensive horseradish peroxidase (HRP) mimic enzyme with potential applications in bio-detection.
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Cites
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
Gao, L., Zhuang, J., Nie, L., Zhang, J., Zhang, Y., Gu, N., Wang, T., Feng, J., Yang, D., Perrett, S., et al. (2007) · Nature Nanotechnology · doi:10.1038/nnano.2007.260 · Cited by 7,483
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Cited by
Han, L., Li, C., Zhang, T., Lang, Q., & Liu, A. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b03591 · Cited by 280
Wang, H., & Huang, Y. (2011) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2011.04.057 · Cited by 109
Metadata
- Authors
- Zhang, X.-Q., Gong, S.-W., Zhang, Y., Yang, T., Wang, C.-Y., & Gu, N.
- Venue
- Journal of Materials Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 20
- Issue
- 24
- Pages
- 5110
- ISSN
- 0959-9428 (ISSN-L)
- 1364-5501
- OpenAlex
- W2159428955
- Cited by
- 382
- References
- 1
- FWCI
- 6.64
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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