The DOI matches its Crossref record; 82 of the 82 references it cites were found in a registry or an index.
Overview of single-cell analyses: microdevices and applications
Abstract
Numerous microdevices developed for single-cell analyses have been presented in the last decades. Practical usefulness in biological and clinical settings has become an important focus during the development and implementation of new structures and assays. Single-cell analysis has been applied in intracellular research, gene- and protein content and expression, PCR, cell culture and division, clone formation, differentiation, morphology, lysis, separation, sorting, cytotoxicity and fluorescence screens, antibody secretion, etc. as discussed here along with brief descriptions of the technical devices used for the studies, e.g. well-, trap-, pattern-, and droplet-based structures. This review aims to serve as an overview of available techniques for single-cell analysis by describing the different biological single-cell assays that have been performed to date and how each individual application requires a particular device design.
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Citations
Cites
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Droplet microfluidic technology for single-cell high-throughput screening
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Cited by
Single Cell Isolation and Analysis
Hu, P., Zhang, W., Xin, H., & Deng, G. (2016) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2016.00116 · Cited by 384
Thompson, B. L., Ouyang, Y., Duarte, G. R. M., Carrilho, E., Krauss, S. T., & Landers, J. P. (2015) · Nature Protocols · doi:10.1038/nprot.2015.051 · Cited by 149
Cancer immunotherapy μ-environment LabChip: taking advantage of optoelectronic tweezers
Ke, L.-Y., Kuo, Z.-K., Chen, Y.-S., Yeh, T.-Y., Dong, M., Tseng, H.-W., & Liu, C.-H. (2018) · Lab on a Chip · doi:10.1039/c7lc00963a · Cited by 50
Metadata
- Authors
- Lindström, S., & Andersson-Svahn, H.
- Venue
- Lab on a Chip
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 10
- Issue
- 24
- Pages
- 3363
- ISSN
- 1473-0189 (ISSN-L)
- 1473-0197
- OpenAlex
- W2015029046
- Cited by
- 260
- References
- 82
- FWCI
- 13.83
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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