The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.
Luminescent quantum clusters of gold in transferrin family protein, lactoferrin exhibiting FRET
Abstract
We report the synthesis of highly luminescent, water soluble quantum clusters (QCs) of gold, which are stabilized by an iron binding transferrin family protein, lactoferrin (Lf). The synthesized AuQC@Lf clusters were characterized using UV-Visible spectroscopy, X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), photoluminescence (PL), matrix assisted laser desorption ionization mass spectrometry (MALDI-MS), FTIR spectroscopy and circular dichroism (CD) spectroscopy along with picosecond-resolved lifetime measurements. Detailed investigations with FTIR and CD spectroscopy have revealed changes in the secondary structure of the protein in the cluster. We have also studied Förster resonance energy transfer (FRET) occurring between the protein and the cluster. The ability of the clusters to sense cupric ions selectively at ppm concentrations was tested. The stability of clusters in widely varying pH conditions and their continued luminescence make it feasible for them to be used for intracellular imaging and molecular delivery, particularly in view of Lf protection.
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Probing the Cytotoxicity of Semiconductor Quantum Dots
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Cited by
Engineering ultrasmall water-soluble gold and silver nanoclusters for biomedical applications
Luo, Z., Zheng, K., & Xie, J. (2014) · Chem. Commun. · doi:10.1039/c3cc47512c · Cited by 441
Liu, F., Sun, C., Yang, W., Yuan, F., & Gao, Y. (2015) · RSC Advances · doi:10.1039/c4ra10802g · Cited by 334
Luminescent Noble Metal Nanoclusters as an Emerging Optical Probe for Sensor Development
Yuan, X., Luo, Z., Yu, Y., Yao, Q., & Xie, J. (2013) · Chemistry – An Asian Journal · doi:10.1002/asia.201201236 · Cited by 328
Uma Suganya, K. S., Govindaraju, K., Ganesh Kumar, V., Stalin Dhas, T., Karthick, V., Singaravelu, G., & Elanchezhiyan, M. (2015) · Materials Science and Engineering: C · doi:10.1016/j.msec.2014.11.043 · Cited by 260
Ghahremani, F., Kefayat, A., Shahbazi-Gahrouei, D., Motaghi, H., Mehrgardi, M. A., & Haghjooy-Javanmard, S. (2018) · Nanomedicine · doi:10.2217/nnm-2018-0180 · Cited by 70
Metadata
- Authors
- Xavier, P. L., Chaudhari, K., Verma, P. K., Pal, S. K., & Pradeep, T.
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2010
- Volume
- 2
- Issue
- 12
- Pages
- 2769
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W2014057693
- Cited by
- 274
- References
- 37
- FWCI
- 10.35
- Type
- journal article
- Language
- en
- Open access
- closed
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