The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.
Silica-based nanoprobes for biomedical imaging and theranostic applications
Open accessAbstract
Nanoparticle-based contrast agents are attracting a great deal of attention for various biomedical imaging and theranostic applications. Compared to conventional contrast agents, nanoparticles possess several potential advantages to improve in vivo detection and to enhance targeting efficiency. Silica-based nanoprobes can be engineered to achieve longer blood circulation times, specific clearance pathways, and multivalent binding. In this tutorial review, we summarize the latest progress on designing silica-based nanoprobes for imaging and theranostic applications. The synthesis of both solid silica and mesoporous silica nanoparticles is described, along with different approaches used for surface functionalization. Special emphasis is placed on the application of silica-based nanoprobes in optical, magnetic resonance, and multimodal imaging. The latest breakthroughs in the applications of silica nanoparticles as theranostic agents are also highlighted.
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Cites
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Cited by
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Mesoporous Silica Nanoparticles for Drug Delivery
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Mesoporous silica nanoparticles in target drug delivery system: A review
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Chemical Synthesis and Assembly of Uniformly Sized Iron Oxide Nanoparticles for Medical Applications
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Metadata
- Authors
- Vivero-Escoto, J. L., Huxford-Phillips, R. C., & Lin, W.
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2012
- Volume
- 41
- Issue
- 7
- Pages
- 2673
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2057610600
- Cited by
- 381
- References
- 55
- FWCI
- 3.95
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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