The DOI matches its Crossref record; 61 of the 61 references it cites were found in a registry or an index.
Mesoporous silica nanoparticles in target drug delivery system: A review
Open accessAbstract
Due to lack of specification and solubility of drug molecules, patients have to take high doses of the drug to achieve the desired therapeutic effects for the treatment of diseases. To solve these problems, there are various drug carriers present in the pharmaceuticals, which can used to deliver therapeutic agents to the target site in the body. Mesoporous silica materials become known as a promising candidate that can overcome above problems and produce effects in a controllable and sustainable manner. In particular, mesoporous silica nanoparticles (MSNs) are widely used as a delivery reagent because silica possesses favorable chemical properties, thermal stability, and biocompatibility. The unique mesoporous structure of silica facilitates effective loading of drugs and their subsequent controlled release of the target site. The properties of mesoporous, including pore size, high drug loading, and porosity as well as the surface properties, can be altered depending on additives used to prepare MSNs. Active surface enables functionalization to changed surface properties and link therapeutic molecules. They are used as widely in the field of diagnosis, target drug delivery, bio-sensing, cellular uptake, etc., in the bio-medical field. This review aims to present the state of knowledge of silica containing mesoporous nanoparticles and specific application in various biomedical fields.
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Cites
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Cited by
Controlled Drug Delivery Systems: Current Status and Future Directions
Adepu, S., & Ramakrishna, S. (2021) · Molecules · doi:10.3390/molecules26195905 · Cited by 1,691
Nanotechnologies in Food Science: Applications, Recent Trends, and Future Perspectives
Nile, S. H., Baskar, V., Selvaraj, D., Nile, A., Xiao, J., & Kai, G. (2020) · Nano-Micro Letters · doi:10.1007/s40820-020-0383-9 · Cited by 631
Nanocarrier-based systems for targeted and site specific therapeutic delivery
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Metadata
- Authors
- Bharti, C., Gulati, N., Nagaich, U., & Pal, A.
- Venue
- International Journal of Pharmaceutical Investigation
- Publisher
- Manuscript Technomedia LLP
- Published
- 2015
- Volume
- 5
- Issue
- 3
- Pages
- 124
- ISSN
- 2230-9713 (ISSN-L)
- 2230-973X
- OpenAlex
- W1908453662
- Cited by
- 817
- References
- 61
- FWCI
- 15.99
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Bharti, C., Gulati, N., Nagaich, U., & Pal, A. (2015). Mesoporous silica nanoparticles in target drug delivery system: A review. International Journal of Pharmaceutical Investigation. https://doi.org/10.4103/2230-973x.160844
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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