The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
The toxic effect of silver ions and silver nanoparticles towards bacteria and human cells occurs in the same concentration range
Abstract
Silver is commonly used both in ionic form and in nanoparticulate form as a bactericidal agent. This is generally ascribed to a higher toxicity towards prokaryotic cells than towards mammalian cells. Comparative studies with both silver ions (such as silver acetate) and polyvinylpyrrolidone (PVP)-stabilized silver nanoparticles (70 nm) showed that the toxic effect of silver occurs in a similar concentration range for Escherichia coli, Staphylococcus aureus, human mesenchymal stem cells (hMSCs), and peripheral blood mononuclear cells (PBMCs), i.e. 0.5 to 5 ppm for silver ions and 12.5 to 50 ppm for silver nanoparticles. For a better comparison, bacteria were cultivated both in Lysogeny broth medium (LB) and in Roswell Park Memorial Institute medium (RPMI)/10% fetal calf serum (FCS) medium, as the state of silver ions and silver nanoparticles may be different due to the presence of salts, and biomolecules like proteins. The effective toxic concentration of silver towards bacteria and human cells is almost the same.
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Cites
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Cited by
Qian, Y., Zhou, X., Zhang, F., Diekwisch, T. G. H., Luan, X., & Yang, J. (2019) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.9b07053 · Cited by 235
Measuring direct current trans-epithelial electrical resistance in organ-on-a-chip microsystems
Odijk, M., van der Meer, A. D., Levner, D., Kim, H. J., van der Helm, M. W., Segerink, L. I., Frimat, J.-P., Hamilton, G. A., Ingber, D. E., & van den Berg, A. (2015) · Lab on a Chip · doi:10.1039/c4lc01219d · Cited by 209
Metadata
- Authors
- Greulich, C., Braun, D., Peetsch, A., Diendorf, J., Siebers, B., Epple, M., & Köller, M.
- Venue
- RSC Advances
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2012
- Volume
- 2
- Issue
- 17
- Pages
- 6981
- ISSN
- 2046-2069 (ISSN-L)
- OpenAlex
- W2159898289
- Cited by
- 389
- References
- 43
- FWCI
- 8.25
- Type
- journal article
- Language
- en
- Open access
- closed
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- Greulich, C., Braun, D., Peetsch, A., Diendorf, J., Siebers, B., Epple, M., & Köller, M. (2012). The toxic effect of silver ions and silver nanoparticles towards bacteria and human cells occurs in the same concentration range. RSC Advances. https://doi.org/10.1039/c2ra20684f
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
