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Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications
Abstract
In recent years low molecular mass organic gelators (LMOGs) have gained increasing interest as an alternative biomaterial to polymer derived gels, with potential applications in drug delivery and tissue engineering. LMOGs are small organic molecules which self-assemble in water or organic solvents forming a 3D network that entraps the liquid phase resulting in gel formation. In this review, we report the classification of LMOGs into hydrogelators and gelators of organic solvents and we discuss the techniques commonly used to characterise the gels of these gelators with particular reference to specific applications of LMOGs in drug delivery and tissue engineering.
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Cites
Hydrogels for tissue engineering: scaffold design variables and applications
Drury, J. L., & Mooney, D. J. (2003) · Biomaterials · doi:10.1016/s0142-9612(03)00340-5 · Cited by 5,136
Cited by
Okesola, B. O., & Smith, D. K. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00124f · Cited by 760
Amabilino, D. B., Smith, D. K., & Steed, J. W. (2017) · Chemical Society Reviews · doi:10.1039/c7cs00163k · Cited by 720
Amino Acids and Peptide‐Based Supramolecular Hydrogels for Three‐Dimensional Cell Culture
Dou, X., & Feng, C. (2017) · Advanced Materials · doi:10.1002/adma.201604062 · Cited by 355
Supramolecular gels made from nucleobase, nucleoside and nucleotide analogs
Peters, G. M., & Davis, J. T. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00183a · Cited by 287
Metadata
- Authors
- Skilling, K. J., Citossi, F., Bradshaw, T. D., Ashford, M., Kellam, B., & Marlow, M.
- Venue
- Soft Matter
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2014
- Volume
- 10
- Issue
- 2
- Pages
- 237-256
- ISSN
- 1744-683X (ISSN-L)
- 1744-6848
- OpenAlex
- W2108587906
- Cited by
- 359
- References
- 1
- FWCI
- 10.90
- Type
- journal article
- Language
- en
- Open access
- closed
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- Skilling, K. J., Citossi, F., Bradshaw, T. D., Ashford, M., Kellam, B., & Marlow, M. (2014). Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications. Soft Matter. https://doi.org/10.1039/c3sm52244j
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
