Review on ion mobility spectrometry. Part 1: current instrumentation
Open accessAbstract
Ion Mobility Spectrometry (IMS) is a widely used and 'well-known' technique of ion separation in the gaseous phase based on the differences in ion mobilities under an electric field. All IMS instruments operate with an electric field that provides space separation, but some IMS instruments also operate with a drift gas flow that provides also a temporal separation. In this review we will summarize the current IMS instrumentation. IMS techniques have received an increased interest as new instrumentation and have become available to be coupled with mass spectrometry (MS). For each of the eight types of IMS instruments reviewed it is mentioned whether they can be hyphenated with MS and whether they are commercially available. Finally, out of the described devices, the six most-consolidated ones are compared. The current review article is followed by a companion review article which details the IMS hyphenated techniques (mainly gas chromatography and mass spectrometry) and the factors that make the data from an IMS device change as a function of device parameters and sampling conditions. These reviews will provide the reader with an insightful view of the main characteristics and aspects of the IMS technique.
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Analyte separations within the vacuum of an MS instrument are possible, enabled by differences in gas phase ion mobility.
“Analyte separations within the vacuum of an MS instrument are also possible, enabled by differences in gas phase ion mobility [62].”
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Gridless Overtone Mobility Spectrometry
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Cited by
Sorted by citations
Liu, Y., D'Agostino, L. A., Qu, G., Jiang, G., & Martin, J. W. (2019) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2019.02.021 · Cited by 344 · see citing works
Electronic nose: a non-invasive technology for breath analysis of diabetes and lung cancer patients
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- Authors
- Cumeras, R., Figueras, E., Davis, C. E., Baumbach, J. I., & Gràcia, I.
- Affiliations
- Consejo Superior de Investigaciones Científicas (ES)
- University of California, Davis (US)
- Reutlingen University (DE)
- Corresponding author
- Figueras, E.
- Venue
- The Analyst
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 140
- Issue
- 5
- Pages
- 1376-1390
- ISSN
- 0003-2654 (ISSN-L)
- 1364-5528
- PMC
- PMC4331213
- OpenAlex
- W2135378461
- Cited by
- 459
- References
- 132
- Citations by year
- 2026: 23 · 2025: 34 · 2024: 35 · 2023: 39 · 2022: 50 · 2021: 60 · 2020: 47 · 2019: 55 · 2018: 51 · 2017: 28 · 2016: 23 · 2015: 12 · 2014: 1
- FWCI
- 2.09
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Analyst (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Reutlingen University Academic Bibliography (Reutlingen University) (submittedVersion)
- Funders
- National Science Foundation (1255915)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Mass Spectrometry Techniques and Applications
- Physical Sciences › Chemistry › Spectroscopy › Analytical Chemistry and Chromatography
- Physical Sciences › Engineering › Biomedical Engineering › Advanced Chemical Sensor Technologies
- Keywords
- ion mobility spectrometry, ion mobility, electrostatic separation
- MeSH terms
- Humans, Ions, Mass Spectrometry
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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