The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently
Open accessAbstract
Improving enzymes by directed evolution requires the navigation of very large search spaces; we survey how to do this intelligently.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Trott, O., & Olson, A. J. (2010) · Journal of Computational Chemistry · doi:10.1002/jcc.21334 · Cited by 38,412
The Elements of Statistical Learning
Hastie, T., Tibshirani, R., & Friedman, J. (2009) · Springer Series in Statistics · doi:10.1007/978-0-387-84858-7 · Cited by 25,970
The Elements of Statistical Learning
Hastie, T., Friedman, J., & Tibshirani, R. (2001) · Springer Series in Statistics · doi:10.1007/978-0-387-21606-5 · Cited by 24,162
No free lunch theorems for optimization
Wolpert, D. H., & Macready, W. G. (1997) · IEEE Transactions on Evolutionary Computation · doi:10.1109/4235.585893 · Cited by 14,237
Introduction to information retrieval
(2009) · Choice Reviews Online · doi:10.5860/choice.46-2715 · Cited by 12,278
Introduction to Information Retrieval
Manning, C. D., Raghavan, P., & Schütze, H. (2008) · doi:10.1017/cbo9780511809071 · Cited by 11,288
Friesner, R. A., Banks, J. L., Murphy, R. B., Halgren, T. A., Klicic, J. J., Mainz, D. T., Repasky, M. P., Knoll, E. H., Shelley, M., Perry, J. K., et al. (2004) · Journal of Medicinal Chemistry · doi:10.1021/jm0306430 · Cited by 10,057
Efficient Global Optimization of Expensive Black-Box Functions
Jones, D. R., Schonlau, M., & Welch, W. J. (1998) · Journal of Global Optimization · doi:10.1023/a:1008306431147 · Cited by 8,070
The Origins of Order: Self-Organization and Selection in Evolution
Kauffman, S. A. (1993) · doi:10.1093/oso/9780195079517.001.0001 · Cited by 7,855
Principles that Govern the Folding of Protein Chains
Anfinsen, C. B. (1973) · Science · doi:10.1126/science.181.4096.223 · Cited by 7,096
Cited by
Role of Biocatalysis in Sustainable Chemistry
Sheldon, R. A., & Woodley, J. M. (2018) · Chemical Reviews · doi:10.1021/acs.chemrev.7b00203 · Cited by 1,755
Mutation effects predicted from sequence co-variation
Hopf, T. A., Ingraham, J. B., Poelwijk, F. J., Schärfe, C. P. I., Springer, M., Sander, C., & Marks, D. S. (2017) · Nature Biotechnology · doi:10.1038/nbt.3769 · Cited by 775
A robotic multidimensional directed evolution approach applied to fluorescent voltage reporters
Piatkevich, K. D., Jung, E. E., Straub, C., Linghu, C., Park, D., Suk, H.-J., Hochbaum, D. R., Goodwin, D., Pnevmatikakis, E., Pak, N., et al. (2018) · Nature Chemical Biology · doi:10.1038/s41589-018-0004-9 · Cited by 319
The Hitchhiker's guide to biocatalysis: recent advances in the use of enzymes in organic synthesis
Sheldon, R. A., Brady, D., & Bode, M. L. (2020) · Chemical Science · doi:10.1039/c9sc05746c · Cited by 299
UniKP: a unified framework for the prediction of enzyme kinetic parameters
Yu, H., Deng, H., He, J., Keasling, J. D., & Luo, X. (2023) · Nature Communications · doi:10.1038/s41467-023-44113-1 · Cited by 226
Metadata
- Authors
- Currin, A., Swainston, N., Day, P. J., & Kell, D. B.
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2015
- Volume
- 44
- Issue
- 5
- Pages
- 1172-1239
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W2160719116
- Cited by
- 388
- References
- 63
- FWCI
- 2.76
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently. https://app.cochat.ai/papers/10.1039/c4cs00351a
- The paper
- Currin, A., Swainston, N., Day, P. J., & Kell, D. B. (2015). Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently. Chemical Society Reviews. https://doi.org/10.1039/c4cs00351a
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.