Cited by 56Garlic and Onion StudiesSpinal Cord Injury ResearchHeat shock proteins research

Allicin protects spinal cord neurons from Glutamate-induced oxidative stress through regulating the heat shock protein 70/inducible nitric oxide synthase pathway

Liu, Shu-Guang, Ren, Peng-Yu, Wang, Guo-Yu, Yao, Shu-Xin, He, Xi-Jing·2015·Food & Function

Abstract

We demonstrate that allicin may be used as an effective treatment for spinal cord injury, and that the potential underlying mechanism involves HSP70/iNOS pathway-mediated inhibition of oxidative stress.

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Crossref · 10.1039/c4fo00761a

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64 of 64 references verified0 citation errors · 0 not checkable

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Authors
Liu, S.-G., Ren, P.-Y., Wang, G.-Y., Yao, S.-X., & He, X.-J.
Affiliations
  • Xi'an Honghui Hospital (CN)
  • Department of Neurosurgery
  • Department of Orthopaedics
Venue
Food & Function
Published
2015
Volume
6
Issue
1
Pages
320-329
ISSN
  • 2042-6496 (ISSN-L)
  • 2042-650X
OpenAlex
W1972851617
Cited by
56
References
64
Citations by year
2026: 3 · 2025: 5 · 2024: 2 · 2023: 4 · 2022: 7 · 2021: 7 · 2020: 4 · 2019: 7 · 2018: 2 · 2017: 7 · 2016: 4 · 2015: 4
FWCI
5.83
Type
journal article
Language
en
Open access
closed
Locations
  • Food & Function (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Garlic and Onion Studies
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Spinal Cord Injury Research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Heat shock proteins research
Keywords
allicin, spinal cord injury, glutamate excitotoxicity, oxidative stress, HSP70, inducible nitric oxide synthase, neuronal apoptosis, neuroprotection, garlic, reactive oxygen species, lipid peroxidation, antioxidant enzymes, neuronal NOS
MeSH terms
Animals, Animals, Newborn, Antioxidants, Cell Survival, Cells, Cultured, Disulfides, Embryo, Mammalian, Gene Expression Regulation, Nerve Tissue Proteins, Neurons, Spinal Cord, Sulfinic Acids, Lipid Peroxidation, Apoptosis, Reactive Oxygen Species, Oxidative Stress, Neuroprotective Agents, Glutamic Acid, HSP70 Heat-Shock Proteins, RNA Interference, Rats, Nitric Oxide Synthase Type II, Phytochemicals

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