Phycocyanin prevents methylglyoxal-induced mitochondrial-dependent apoptosis in INS-1 cells by Nrf2
Abstract
Phycocyanin prevents mitochondrial-dependent apoptosis in methylgiyoxal-induced INS-1 cells by activating Nrf2.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
C-phycocyanin inhibits NF-kB and induces Nrf2 activation in pancreatic β-cell INS-1.
“In particular, C-phycocyanin was able to inhibit NF-kB [54] and induced Nrf2 activation in pancreatic β-cell INS-1 [55].”
From Antioxidant, Immunomodulating, and Microbial‐Modulating Activities of the Sustainable and Ecofriendly <i>Spirulina</i> (2017) · cites this paper as [55]
The citation lists haven’t been fetched yet
References 51 · Cited by 43
- Authors
- Gao, Y., Liu, C., Wan, G., Wang, X., Cheng, X., & Ou, Y.
- Affiliations
- China Pharmaceutical University (CN)
- Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (US)
- Corresponding author
- Ou, Yu
- Venue
- Food & Function
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2016
- Volume
- 7
- Issue
- 2
- Pages
- 1129-1137
- ISSN
- 2042-6496 (ISSN-L)
- 2042-650X
- OpenAlex
- W2229964270
- Cited by
- 43
- References
- 51
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 4 · 2023: 3 · 2022: 6 · 2021: 3 · 2020: 5 · 2019: 1 · 2018: 5 · 2017: 5 · 2016: 1
- FWCI
- 2.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food & Function (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics, phytochemicals, and oxidative stress
- Health Sciences › Medicine › Surgery › Pancreatic function and diabetes
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
- Keywords
- phycocyanin, methylglyoxal, mitochondrial-dependent apoptosis, Nrf2, INS-1 cells, pancreatic beta cells, type 2 diabetes, mitochondrial dysfunction, reactive oxygen species, cytochrome c release, apoptosis-inducing factor, Bcl-2 family proteins, caspase activation, heme oxygenase-1, glyoxalase I, antioxidant enzymes, dicarbonyl compounds
- MeSH terms
- Insulin Secretion, Antioxidants, Cells, Cultured, Humans, Insulin, Lactoylglutathione Lyase, Mitochondria, Phycocyanin, Pyruvaldehyde, Apoptosis, Reactive Oxygen Species, Oxidative Stress, Cytochromes c, Insulin-Secreting Cells, bcl-2-Associated X Protein, Apoptosis Inducing Factor, NF-E2-Related Factor 2, Heme Oxygenase-1
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
