The preparation and characterization of nitric oxide releasing silicone rubber materials impregnated with S-nitroso-tert-dodecyl mercaptan
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bacteria. The use of such lipophilic RSNO impregnated silicone rubber tubing could dramatically reduce the risk of catheter-related infections, which are a common problem associated with placement of intravascular or urinary catheters.
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Colletta et al. and Ketchum et al. loaded silicone tubing with NO donors (SNAP and lipophilic SNAP derivatives) and demonstrated antibacterial effects toward several microorganisms, including S. epidermis, P. mirabilis, and S. aureus.
“In subsequent studies, Colletta et al.19 and Ketchum et al.189 used the solvent impregnation method previously described above (see section Physical Encapsulation-based NO Releasing Polymers) to load silicone-based tubing with NO donors (SNAP and lipophilic SNAP derivatives, respectively) and demonstrated that they have antibacterial effects toward several microorganisms (e.g., Staphylococcus epid”
From Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO) (2016) · cites this paper as [189]
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Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices
Lee, J. N., Park, C., & Whitesides, G. M. (2003) · Analytical Chemistry · doi:10.1021/ac0346712 · Cited by 2,643 · see citing works
Colletta, A., Wu, J., Wo, Y., Kappler, M., Chen, H., Xi, C., & Meyerhoff, M. E. (2015) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.5b00032 · Cited by 89 · see citing works
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Wo, Y., Brisbois, E. J., Bartlett, R. H., & Meyerhoff, M. E. (2016) · Biomaterials Science · doi:10.1039/c6bm00271d · Cited by 251 · see citing works
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- Authors
- Ketchum, A. R., Kappler, M. P., Wu, J., Xi, C., & Meyerhoff, M. E.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Meyerhoff, Mark E.
- Venue
- Journal of Materials Chemistry B
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2016
- Volume
- 4
- Issue
- 3
- Pages
- 422-430
- ISSN
- 2050-750X (ISSN-L)
- 2050-7518
- PMC
- PMC4826759
- OpenAlex
- W2191968953
- Cited by
- 28
- References
- 2
- Citations by year
- 2026: 1 · 2024: 5 · 2022: 2 · 2021: 5 · 2020: 3 · 2019: 2 · 2018: 6 · 2017: 2 · 2016: 2
- FWCI
- 1.53
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Materials Chemistry B (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (EB-000783)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Antimicrobial agents and applications
- Health Sciences › Medicine › Physiology › Nitric Oxide and Endothelin Effects
- Physical Sciences › Engineering › Building and Construction › Dyeing and Modifying Textile Fibers
- Keywords
- nitric oxide release, silicone rubber, catheter-related infection, antibacterial materials, intravascular catheters, urinary catheter
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