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Recent progress in biomedical applications of persistent luminescence nanoparticles
Abstract
Persistent luminescence nanoparticles (PLNPs) are an emerging group of promising luminescent materials that can remain luminescent after the excitation ceases. In the past decade, PLNPs with intriguing optical properties have been developed and their applications in biomedicine have been widely studied. Due to the ultra-long decay time of persistent luminescence, autofluorescence interference in biosensing and bioimaging can be efficiently eliminated. Moreover, PLNPs can remain luminescent for hours, making them valuable in bio-tracing. Also, persistent luminescence imaging can guide cancer therapy with a high signal-to-noise ratio (SNR) and superior sensitivity. Briefly, PLNPs are demonstrated to be a newly-emerging class of functional materials with unprecedented advantages in biomedicine. In this review, we summarized recent advances in the preparation of PLNPs and the applications of PLNPs in biosensing, bioimaging and cancer therapy.
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Second window for in vivo imaging
Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848
Cited by
Molecular Probes for Autofluorescence-Free Optical Imaging
Jiang, Y., & Pu, K. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00506 · Cited by 426
Sun, S.-K., Wang, H.-F., & Yan, X.-P. (2018) · Accounts of Chemical Research · doi:10.1021/acs.accounts.7b00619 · Cited by 384
Tan, H., Wang, T., Shao, Y., Yu, C., & Hu, L. (2019) · Frontiers in Chemistry · doi:10.3389/fchem.2019.00387 · Cited by 59
Metadata
- Authors
- Wang, J., Ma, Q., Wang, Y., Shen, H., & Yuan, Q.
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2017
- Volume
- 9
- Issue
- 19
- Pages
- 6204-6218
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W2606790836
- Cited by
- 200
- References
- 1
- FWCI
- 9.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wang, J., Ma, Q., Wang, Y., Shen, H., & Yuan, Q. (2017). Recent progress in biomedical applications of persistent luminescence nanoparticles. Nanoscale. https://doi.org/10.1039/c7nr01488k
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