Diblock copolymer glyco-nanomicelles constructed by a maltoheptaose-based amphiphile for reduction- and pH-mediated intracellular drug delivery
Abstract
A new type of reduction- and pH-mediated glyco-polymeric micelles was synthesized for the antitumor drug doxorubicin (DOX) delivery in this study.
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DOX-encapsulated MH-S-S-AcMH micelles revealed improved cytotoxicity to HeLa cells than bare DOX.
“Moreover, DOX-encapsulated micelles revealed improved cytotoxicity to HeLa cells than bare DOX.”
From Recent Advances in Nanomicelles Delivery Systems. (2020) · cites this paper as [155]
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Recent Advances in Nanomicelles Delivery Systems.
Tawfik, S. M., Azizov, S., Elmasry, M. R., Sharipov, M., & Lee, Y.-I. (2020) · Nanomaterials · doi:10.3390/nano11010070 · Cited by 156 · see citing works
- Authors
- Cheng, L., Luan, T., Liu, D., Cheng, J., Li, H., Wei, H., Zhang, L., Lan, J., Liu, Y., & Zhao, G.
- Affiliations
- State Key Laboratory of Applied Organic Chemistry (CN)
- Lanzhou University (CN)
- Gansu Provincial Maternal and Child Health Hospital (CN)
- Corresponding author
- Zhao, Guanghui
- Venue
- Polymer Chemistry
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2018
- Volume
- 9
- Issue
- 11
- Pages
- 1337-1347
- ISSN
- 1759-9954 (ISSN-L)
- 1759-9962
- OpenAlex
- W2788424675
- Cited by
- 13
- References
- 32
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 1 · 2023: 1 · 2022: 2 · 2020: 1 · 2019: 4
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Polymer Chemistry (publishedVersion)
- Lanzhou University Institutional Repository (submittedVersion)
- Funders
- National Natural Science Foundation of China (21772080)
- Natural Science Foundation of Gansu Province (1506RJYA221)
- Topics
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Physical Sciences › Materials Science › Polymers and Plastics › Dendrimers and Hyperbranched Polymers
- Physical Sciences › Chemistry › Organic Chemistry › Advanced Polymer Synthesis and Characterization
- Keywords
- diblock copolymer micelles, maltoheptaose, amphiphilic molecules, pH-responsive drug delivery, intracellular drug delivery, doxorubicin, anticancer drug delivery, polymeric micelles
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