Concentration gradient generation methods based on microfluidic systems

Cited by (218)

Items 101–200 of 218

1. Flow regimes of the immiscible liquids within a rectangular microchannel
   Xiang Wang, Yan Pang, Yilin Ma, Yanlin Ren, Zhaomiao Liu · 2021 · Acta Mechanica Sinica
2. Complete experimental and theoretical characterization of nonlinear concentration gradient generator microfluidic device for analytical purposes
   Paulo Henrique M. Buzzetti, Maiara Mitiko Taniguchi, Nayara de Souza Mendes, Renata Corrêa Vicentino, Jean Halison de Oliveira, Bento Pereira Cabral Júnior, Marcos de Almeida Souza, Johny P. Monteiro, Emerson Marcelo Girotto · 2021 · Microchimica Acta
3. Efficient Generation of Dilution Gradients With Digital Microfluidic Biochips
   Sukanta Bhattacharjee, Ansuman Banerjee, Tsung-Yi Ho, Krishnendu Chakrabarty, Bhargab B. Bhattacharya · 2018 · IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems
4. Electrochemical Generation of Steady-State Linear Concentration Gradients within Microfluidic Channels Perpendicular to the Flow Field
   Pierre Perrodin, Sella Catherine, Laurent Thouin · 2020 · Analytical Chemistry
5. A microfluidic platform enabling real-time control of dynamic biochemical stimuli to biological cells
   Chun‐Dong Xue, Yong‐Jiang Li, Jing‐Tong Na, Yanxia Wang, Hongjian Yu, Bo Liu, Tun Cao, Kai‐Rong Qin · 2020 · Journal of Micromechanics and Microengineering
6. Integration of Electrospray and Digital Light Processing for Freeform Patterning of Porous Microstructures
   Yue Kai Xue, Lin Qi, Ye Niu, Hanyang Huang, Fangsheng Huang, Ting Si, Yi Zhao, Ronald X. Xu · 2020 · Advanced Materials Technologies
7. Multi-fidelity reduced-order model for GPU-enabled microfluidic concentration gradient design
   Haizhou Yang, Seong Hyeon Hong, Gang Wang, Yi Wang · 2022 · Engineering With Computers
8. Toxicity of trastuzumab for breast cancer spheroids: Application of a novel on-a-chip concentration gradient generator
   Shabnam Shahrivari, Neda Aminoroaya, Roya Ghods, Hamid Latifi, Seyedeh Atiyeh Afjei, Neda Saraygord‐Afshari, Zeinab Bagheri · 2022 · Biochemical Engineering Journal
9. A Perfluoropolyether Microfluidic Device for Cell-Based Drug Screening with Accurate Quantitative Analysis
   Hyun Sun Choi, Gwang‐Noh Ahn, Gi-Su Na, Hyung Joon Chi, Dong‐Pyo Kim · 2022 · ACS Biomaterials Science & Engineering
10. An embedded obstacle type micromixer‐concentration gradient generator based on capillary driven
    Sisi Huang, Yihao Wu, Yifan Wang, Xiaoling Hu, Kui Song · 2023 · Electrophoresis
11. Multi-layered Microfluidic Drug Screening Platform Enabling Simultaneous Generation of Linear and Logarithmic Concentration Gradients
    Jung Yun Susan Yoon, Joonha Park, Hyeono Nam, Seunggyu Kim, Jessie Sungyun Jeon · 2024 · BioChip Journal
12. Pre-programmed microdroplet generator to control wide-ranging chemical concentrations
    Md. Ahasan Ahamed, Geunyong Kim, Zhenglin Li, Sung‐Jin Kim · 2022 · Analytica Chimica Acta
13. When Super‐Resolution Microscopy Meets Microfluidics: Enhanced Biological Imaging and Analysis with Unprecedented Resolution
    Wei Yang, Lei Hou, Chunxiong Luo · 2023 · Small
14. Recent Developments in Bacterial Chemotaxis Analysis Based on the Microfluidic System
    Heon‐Ho Jeong · 2020 · SLAS TECHNOLOGY
15. Breakup a droplet passing through an obstacle in an orthogonal cross-section microchannel
    Erfan Kadivar, Fatemeh Zarei · 2021 · Theoretical and Computational Fluid Dynamics
16. Flexible Toolbox of High-Precision Microfluidic Modules for Versatile Droplet-Based Applications
    Mario Saupe, Stefan Wiedemeier, Gunter Gastrock, Robert Römer, Karen Lemke · 2024 · Micromachines
17. GPU-enabled microfluidic design automation for concentration gradient generators
    Seong Hyeon Hong, Jung I. Shu, Junlin Ou, Yi Wang · 2022 · Engineering With Computers
18. Conventional and Microfluidic Methods for the Detection of Nucleic Acid of SARS-CoV-2
    Weidu Song, Taiyi Zhang, Huichao Lin, Yujing Yang, Gaozhen Zhao, Xiaowen Huang · 2022 · Micromachines
19. Micro-hydrogel molding-assisted fabrication of a PDMS-based microfluidic concentration-gradient generator for dynamic anticancer drug testing
    Dhruba Dhar, Jyotirmoy Chatterjee, Soumen Das · 2025 · RSC Advances
20. Harnessing Synergies between Combinatorial Microfluidics and Machine Learning for Chemistry, Biology, and Fluidic Design
    Suyash S. Damir, Julie Probst, Andrew J. deMello, Stavros Stavrakis · 2025 · Chemistry - Methods
21. Engineering approaches to control and design the in vitro environment towards the reconstruction of organs
    Masaya Hagiwara, Isabel Koh · 2020 · Development Growth & Differentiation
22. A Hybrid Microfluidic Differential Carbonator Approach for Enhancing Microalgae Growth: Inline Monitoring Through Optical Imaging
    Hayat Abdulla Yusuf, S. M. Zakir Hossain, Ahmed Ali Khamis, Hassan Tariq Radhi, Ahmed Salman Jaafar, Peter R. Fielden · 2021 · Arabian Journal for Science and Engineering
23. Patterning Neuroepithelial Cell Sheet via a Sustained Chemical Gradient Generated by Localized Passive Diffusion Devices
    Ningwei Li, Feiyu Yang, Subiksha Parthasarathy, Skyler R. St. Pierre, Kelly Hong, Narciso Pavon, ChangHui Pak, Yubing Sun · 2021 · ACS Biomaterials Science & Engineering
24. White calibration methods based on gradient techniques as a modern approach to quantitative flow analysis
    Paweł Kościelniak · 2022 · TrAC Trends in Analytical Chemistry
25. Towards Three-Dimensional Dynamic Regulation and In Situ Characterization of Single Stem Cell Phenotype Using Microfluidics
    Sébastien Sart, Spiros Nicolas Agathos · 2018 · Molecular Biotechnology
26. GNN-Based Concentration Prediction With Variable Input Flow Rates for Microfluidic Mixers
    Weiqing Ji, Xingzhuo Guo, Shouan Pan, Fei Long, Tsung-Yi Ho, Ulf Schlichtmann, Hailong Yao · 2024 · IEEE Transactions on Biomedical Circuits and Systems
27. CFD for Microfluidics: A Workflow for Setting Up the Simulation of Microfluidic Devices
    Philipp Ebner, Robert Wille · 2023 · Euromicro Conference on Digital System Design (DSD)
28. Thinning dynamics of the liquid thread at different stages in a rectangular cross junction
    Xiang Wang, Yan Pang, Yilin Ma, Yanlin Ren, Zhaomiao Liu · 2022 · AIChE Journal
29. Microfluidic Network Simulations Enable On-Demand Prediction of Control Parameters for Operating Lab-on-a-Chip-Devices
    Julia Sophie Böke, Daniel J. Kraus, Thomas Henkel · 2021 · Processes
30. Abnormal Liquid Chasing Effect in Paper Capillary Enables Versatile Gradient Generation on Microfluidic Paper Analytical Devices
    Yu Liu, Jin-Wen Shangguan, Bi-Yi Xu, Xiaodong Yu, Jing‐Juan Xu, Hong‐Yuan Chen · 2020 · Analytical Chemistry
31. Current Trends in Microfluidics and Biosensors for Cancer Research Applications
    David Caballero, Rui Luís Reis, Subhas Chandra Kundu · 2022 · Advances in experimental medicine and biology
32. 3D printed microfluidic devices produced by material extrusion: effect of ironing parameters on mixing efficiency and gradient generation
    Alessio Pricci, Gianluca Percoco · 2024 · Rapid Prototyping Journal
33. Sample Preparation with Free-Flowing Biochips using Microfluidic Binary-Tree Network
    Tapalina Banerjee, Sudip Poddar, Sukanta Bhattacharjee, Yong‐Ak Song, Ajymurat Orozaliev, Bhargab B. Bhattacharya · 2020 · IEEE International Symposium on Circuits and Systems proceedings
34. A sparse multi-fidelity surrogate-based optimization method with computational awareness
    Haizhou Yang, Yi Wang · 2022 · Engineering With Computers
35. Microfluidic-Based Platform for the Evaluation of Nanomaterial-Mediated Drug Delivery: From High-Throughput Screening to Dynamic Monitoring
    Yamin Yang, Sijia Liu, Jinfa Geng · 2019 · Current Pharmaceutical Design
36. Versatile Macroscale Concentration Gradients of Nanoparticles in Soft Nanocomposites
    Patricia Taladriz‐Blanco, Barbara Rothen‐Rutishauser, Alke Petri‐Fink, Sandor Balog · 2020 · Small
37. A generalized analytical model for investigating flow dynamics influenced by wall wettability in capillary-driven microfluidics
    Sergio Balestrieri, Federica Granata, Mario Iodice, Giuseppe Coppola · 2025 · Microfluidics and Nanofluidics
38. Microfluidics to Meet Antibiotic Resistance: A Growing Research Frontier
    Mikhail Y. Zhitlov, Коршун Владимир Аркадьевич, Vera A. Alferova · 2025 · Antibiotics
39. Chemotactic Interactions of Scenedesmus sp. and Azospirillum brasilense Investigated by Microfluidic Methods
    Erika Greipel, Krisztina Nagy, Eszter Csákvári, László Dér, Péter Galajda, József Kutasi · 2024 · Microbial Ecology
40. Microfluidic chip for synergic drugs assay in 3D breast cancer cell
    Franciele Flores Vit, Yu Tzu Wu, Eric Fujiwara, Hernandes F. Carvalho, Lucimara Gaziola de la Torre · 2024 · Microfluidics and Nanofluidics
41. Flexible and rapid generation of multiple concentration gradients for the protein nanoparticle synthesis
    Haoyang Lu, Zihan Zhou, H. M. i Zou Ping, Haizhen Sun, Lining Sun, Tao Chen · 2024 · Chemical Engineering Journal
42. Dispersion and residence time distribution of laminar tubular flow in the transition regime – models for flow chemistry and beyond
    Martin Wörner · 2025 · Chemical Engineering Science
43. Scalable Multiparametric Characterization of Aptamer–Target Interactions
    Marc Sulliger, Matthew Peters, Andrea Sottini, Annina Stuber, Kyung-Ae Yang, Nako Nakatsuka, Jaime Ortega Arroyo, Romain Quidant · 2026 · ACS Nano
44. Online Monitoring of Cell Growth on PDMS-PDMS Reversible Microfluidic Bioreactor Integrated to Optical Fiber Sensor
    Marco César Prado Soares, Franciele Flores Vit, Lucimara Gaziola de la Torre, Eric Fujiwara · 2019 · SBFoton International Optics and Photonics Conference (SBFoton IOPC)
45. Design Optimization of a 3D Microfluidic Channel System for Biomedical Applications
    Radita Tyas Atsani Susanto, Brijesh Patel, Yu‐Sheng Hsiao, Hsiu-Yang Tseng, Po Ting Lin · 2023 · 3D Printing and Additive Manufacturing
46. Flexible concentration control of Newtonian and non-Newtonian fluids in a microfluidic device via AC electrothermal flow
    Kailiang Zhang, Chen Cai, Haizhen Sun, Na Jia, Jiuqing Liu, Zhijie Xie · 2024 · Sensors and Actuators A Physical
47. Microflow Switching using Artificial Cilia for On‐Demand Particle Manipulation
    Prashant Kishor Sharma, Po‐Wei Wei, Dineshkumar Loganathan, Yueh‐Hsun Lu, Chia‐Yuan Chen · 2025 · Advanced Intelligent Systems
48. Flow-Based Passive Microfluidic Architecture for Homogeneous Mixing
    Tapalina Banerjee, Sudip Poddar, Robert Wille, Bhargab B. Bhattacharya · 2019 · International Symposium on Embedded Computing and System Design (ISED)
49. Reaction–diffusion phenomena in antagonistic bipolar diffusion fields
    Brigitta Dúzs, István Szalai · 2021 · Physical Chemistry Chemical Physics
50. Exploiting a gradient kinetics and color histogram in a single picture to second order digital imaging data acquisition with MCR-ALS for the arsenic quantification in water
    Federico Danilo Vallese, Federico Belén, Paula V. Messina, Adriano Araújo Gomes, Marcelo Fabián Pistonesi · 2021 · Sensors and Actuators B Chemical
51. Droplet-based microfluidics in chemical applications
    Dhruvkumar H. Wankawala, Sudip Shyam, Pranab Kumar Mondal · 2024 · Elsevier eBooks
52. A pump-free dual unidirectional circulation microfluidic device for tumor spheroid microenvironment modulation and motility analysis
    Xiaoqing Chen, Yuanyuan Xie, Wen Feng Sun, Ke Ning, Yi‐Rong Chen, Li Feng, Can Fang, Yan Li, Ling Dan Yu · 2025 · Microchemical Journal
53. Microfluidic engineering of AgNPs@ZIF-8 composites enables tunable peroxidase-like catalytic activity for enhanced bacterial inactivation
    Chong Hu, Juan Tao, Liqiang Zhang, Jiancheng Zha, Panpan Cui, Yanbao Li, Yuan Zhou, Jing Su, Feng Liu, Liangjun Li · 2025 · Chemical Engineering Journal
54. Generation of stable advective-diffusive chemokine gradients in a three-dimensional hydrogel
    Willy V. Bonneuil, Daniel Watson, Jennifer Frattolin, Matthew J. Russell, Francesca Fasanella Masci, Mikaila Bandara, Bindi S. Brook, Robert J. B. Nibbs, James E. Moore · 2022 · AIP Advances
55. Investigation of tumour environments through advancements in microtechnology and nanotechnology
    Zhen Liu, Yan Liang Fan, Mengyao Cui, Xuming Wang, Pengfei Zhao · 2024 · Biomedicine & Pharmacotherapy
56. Flexible Concentration Gradient Droplet Generation via Partitioning–Recombination in a Shear Flow-Driven Multilayer Microfluidic Chip
    Linkai Yu, Qingyang Feng, Yifan Chen, Yongji Wu, Haizhen Sun, Hao Chun Yang, Lining Sun · 2025 · Symmetry
57. Easy Generation of Droplets in a Capillary Inserted Microchannel
    Feng Shen, Jie Chen, Chunyou Li, Yongchun Yuan, Zhaomiao Liu · 2024 · Industrial & Engineering Chemistry Research
58. Bioengineering gradients for controlled embryo and organ modeling
    Shi-Yu Sun, Zhuowei Zhou, Aoife Tang, Jian-Ping Fu · 2025 · Current Opinion in Biomedical Engineering
59. Collision characteristics of droplet pairs with the presence of arriving distance differences
    Xiang Wang, Zhaomiao Liu, Yan Pang · 2018 · Journal of Industrial and Engineering Chemistry
60. A microfluidic platform for anterior-posterior human endoderm patterning via countervailing morphogen gradients in vitro
    Leeya Engel, Kevin J. Liu, Kiara W. Cui, Eva L. de la Serna, Vipul T. Vachharajani, Carolyn E. Dundes, Sherry Li Zheng, Manali Begur, Kyle M. Loh, Lay Teng Ang et al. · 2025 · iScience
61. Nanopore analysis of microfluidically prepared samples using a probe-type lipid bilayer system
    Yanyao Qian, Shun Okada, Kan Shoji · 2025 · Microchemical Journal
62. Analytical Modelling, CFD Simulation, and Experimental Validation of n-butanol-Diesel/Biodiesel Fuel Blends in a Microfluidic System
    Hayat Abdulla Yusuf · 2021 · Arabian Journal for Science and Engineering
63. Analysis of Static Molecular Gradients in a High-Throughput Drug Screening Microfluidic Assay
    Roman G. Szafran, Benita Wiatrak · 2021 · Molecules
64. Multi-fidelity surrogate-based optimization for microfluidic concentration gradient generator design
    Haizhou Yang, Seong Hyeon Hong, Yu Qian, Yi Wang · 2023 · Engineering Computations
65. Fluid dynamic design for mitigating undesired cell effects and its application to testis cell response testing to endocrine disruptors
    Seungjin Lee, Jin Seop Ahn, Seok‐Man Kim, Daehan Kim, Jiun Yeom, Jeongmok Kim, Joong Yull Park, Buom‐Yong Ryu · 2023 · Journal of Biological Engineering
66. Non-Contact Microfluidic Mixing Probe for Generating Controlled Concentration Gradient
    Dima Samer Ali, Ayoub Glia, Pavithra Sukumar, Muhammedin Deliorman, Mohammad Ameen Qasaimeh · 2023 · International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS)
67. A high-throughput flowless microfluidic single and multi-solute concentration gradient generator: Design and parametric study
    Mallikarjun P. V. N. Reddy, Ketaki Bachal, Prasanna S. Gandhi, Abhijit Majumder · 2024 · Biomicrofluidics
68. Parallel dilution microfluidic device for enabling logarithmic concentration generation in molecular diagnostics
    Akira Miyajima, Fumiya Nishimura, Daigo Natsuhara, Yuka Kiba, Shunya Okamoto, Moeto Nagai, Tadashi Yamamuro, Masashi Kitamura, Takayuki Shibata · 2025 · Lab on a Chip
69. Flexible modulation of droplet concentrations via AC electrothermal flow for fabrication of crystalline drug particles
    Kailiang Zhang, Chen Cai, Haizhen Sun, Yupan Wu, Zhijie Xie · 2025 · Sensors and Actuators B Chemical
70. Powder‐Based 3D Printing of Autonomous Concentration Gradient Generators
    Cesar Parra‐Cabrera, Ruben Dochy, Jonas Adriaenssens, Hans Van Cauteren, Agnese Piovesan, Pieter Verboven, Bart M. Nicolaï, Rob Ameloot · 2022 · Advanced Engineering Materials
71. Synthesizing microfluidic networks of one-step-dilution gradient generators with arbitrary concentration profiles
    Ying-Hsuan Chiu, Chia-Yu Cho, Jiun-Jr Hsu, Sheng-Feng Hung, Chih-Lin Huang, Yao-Joe Joseph Yang · 2023 · Sensors and Actuators A Physical
72. Optimization of Bacillus Bacteria Mediated Biosynthesis of Nickel Nanoparticles Using a Precise Gradient Generated Through Microfluidic Network.
    Hayat Abdulla Yusuf, Zainab Mohammed Redha, Salwa Al Thawadi, Husain Maki, Husain Abbas, Jasim Mohamed Mohsin · 2024 · Research Square
73. Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs Migration
    Zhen Xu, Anna Ponek, Jordan L. Thomas, Yibing Qyang · 2025 · ACS Sensors
74. Advances in microfluidic chip technology for cell analysis
    Luxi Shu, Yan Zhang · 2025 · Analytical Sciences
75. EnGRAM: Engineering Open-Space Microfluidic Gradient Modulators
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76. Microfluidic Concentration Manipulation via Controllable AC Electroosmotic Flow
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77. Electroporation of spheroids using an electric field gradient: a tool to study intensity-dependent permeabilization
    Théo Le Berre, Julien Marchalot, Guilhem Rival, Laure Franqueville, Rabia Önbaş, Charlotte Rivière, Gabriel Marcellier, Frédéric Prat, Marie Frénéa‐Robin · 2025 · Lab on a Chip
78. Accessible Ratio-Specific Mixing: Single-Pressure-Driven Multi-Reagent Mixer Design and Synthesis for 3D-Printed Microfluidics
    Yushen Zhang, Debraj Kundu, Tsun‐Ming Tseng, S. Roy, Shigeru Yamashita, Ulf Schlichtmann · 2026 · Asia and South Pacific Design Automation Conference (ASP-DAC)
79. A Microfluidic Gradient Generator Post‐Modified by Two‐Photon Direct Laser Writing for Dynamic Particle Functionalization
    Chantal Barwig, Valerio Chionna, Annabelle Sonn, Kathi Michèle Kaiser, Zhe Wang, Christine Selhuber‐Unkel, Sadaf Pashapour · 2026 · Journal of Applied Polymer Science
80. A Microwell Array Embedded Microfluidic Gradient Platform for Drug Screening on Tumor Spheroids
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81. Experimental and Molecular Simulation Study of Methyl Orange Adsorption on ZIF-67
    Lili Gao, Kalampyr Bexeitova, Inabat Sapargali, Kenes Kudaibergenov, Alzhan Baimenov, Tiancheng You, Сейтхан Азат, Jechan Lee · 2026 · International Journal of Molecular Sciences
82. Microchannels for microfluidic systems
    Behzad Nasseri, Samet Akar, Erdinç Naseri · 2020 · Elsevier eBooks
83. Design and Simulation of an Oxygen Gradient Generator for Heart-on-a-Chip
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84. Embedded screen-printed transducers in bulk polymer microfluidic devices
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85. Microfluidic Technologies for Head and Neck Cancer: From Single-Cell Analysis to Tumor-on-a-Chip
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86. Active matter dynamics in confined microfluidic environments
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87. A Novel Adaptive Sampling Method Based on Expected Improvement Reduction
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88. A Microfluidic Spheroid Culture Device with a Concentration Gradient Generator for High-Throughput Screening of Drug Efficacy
    Wanyoung Lim, Sungsu Park · 2021 · Vide Leaf, Hyderabad eBooks
89. Specific Ionic Recognition Using Fig’s Xylem/Phloem Vessel as a Novel and Applicable Device: Lab-on-a Xylem/Phloem
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90. Lithography-less, frugal and long-term diffusion-based static gradient generating microfluidic device for high-throughput drug testing
    Ketaki Bachal, Shital Yadav, Prasanna S. Gandhi, Abhijit Majumder · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
91. Electrochemical platform of controllable pH gradients in microbial systems
    Jingyu Wang, Yongchao Xie, Yi Chen, Haiyuan Zou, Chong Liu · 2024 · ChemRxiv
92. A Digital Maskless Photolithographic Patterning Method for DNA Based UV Photocleavable PEGDA Hydrogels with A Camphorquinone-Triethanolamine Photoinitiator
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93. Experimental and numerical study of temperature-actuated droplets within microfluidics
    Ali Khater, Asmaa Ali ElAwadi · 2019
94. Cheap, Versatile, and Turnkey Fabrication of Microfluidic Master Molds Using Consumer Grade LCD Stereolithography 3D Printing
    Vincent G. Colin, Théo Travers, Denis Gindre, R. Barillé, Matthieu Loumaigne · 2021 · Research Square
95. Projeto e desenvolvimento de microfermentadores monitorados por sensor de fibra óptica
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96. Synthesis of Thiol-Acrylate Hydrogels for 3D Cell Culture and Microfluidic Applications
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97. Optimization of Biosynthesized Ninps Production Using a Precise Gradient Generation from a Microfluidic Network
    Hayat Abdulla Yusuf, Zainab Mohammed Redha, Salwa Al-Thawadi, Husain Maki, Husain Abbas, Jasim Mohamed Mohsin · 2022 · SSRN Electronic Journal
98. Optimization of Biosynthesized Ninps Production Using a Precise Gradient Generation from a Microfluidic Network
    Hayat Abdulla Yusuf, Zainab Mohammed Redha, Salwa Al-Thawadi, Husain Maki, Husain Abbas, Jasim Mohamed Mohsin · 2022 · SSRN Electronic Journal
99. The Effects of Changing Dynamic Viscosity of Fluid to Velocity, Pressure and Volume Fraction in Co-axial and Tri-Axial Millifluidics
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100. An easy droplet-generation method using an inserted glass capillary into a microchannel
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