Superparamagnetic iron oxide nanoparticulate system: synthesis, targeting, drug delivery and therapy in cancer

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Band gaps and electronic structure of transition-metal compounds

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Breast cancer nanomedicine market update and other industrial perspectives of nanomedicine

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Bioconjugation studies of an EGF-R targeting ligand on dendronized iron oxide nanoparticles to target head and neck cancer cells

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Superparamagnetic iron oxide nanoparticles drive miR-485-5p inhibition in glioma stem cells by silencing Tie1 expression

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Synthesis and characterization of magnetic nanoparticles of cobalt ferrite coated with silica

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Unravelling coexistence of superparamagnetism- soft ferrimagnetism, super-spin glass and Griffith phases in an assembly of greenly synthesized Zn0.5Fe2.5O4 nanopolygons and their magnetic hyperthermia efficiency

Tiwari, S., Yadav, A., Kamali, S., Williams, A., Anandhi, J. S., Johnson, J. A., Johnson, C., Eyal, A., & Kumar, S. (2025) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2025.173118 · Cited by 15

Stimuli-responsive magnetic silica-poly-lactic-co-glycolic acid hybrid nanoparticles for targeted cancer chemo-immunotherapy

Gupta, A., Niveria, K., Chandpa, H. H., Singh, M., Kumar, V., Panda, A. K., & Meena, J. (2024) · Drug Delivery and Translational Research · doi:10.1007/s13346-024-01521-0 · Cited by 15

In vitro Biological Tests as the First Tools To Validate Magnetic Nanotheranostics for Colorectal Cancer Models

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How well can we characterize human serum transformations of magnetic nanoparticles?

Timerbaev, A. R. (2019) · The Analyst · doi:10.1039/c9an01920k · Cited by 15

Coating of SPIONs with a Cysteine-Decorated Copolyester: A Possible Novel Nanoplatform for Enzymatic Release

Beltrame, J. M., Ribeiro, B. B. P., Guindani, C., Candiotto, G., Felipe, K. B., Lucas, R., Zottis, A. D., Isoppo, E. D. A., Sayer, C., & de Araújo, P. H. H. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15031000 · Cited by 14

Reitveld refinement, structural, optical band gap and low-temperature magnetic characterization of Gd3+ doped spinel cubic CoFe2O4 nanoparticles

Kumar, A., Gora, M. K., Kumar, S., Choudhary, B. L., Maheshwari, P., & Dolia, S. N. (2022) · Bangladesh Journal of Scientific and Industrial Research · doi:10.3329/bjsir.v57i3.62019 · Cited by 13

Fabrication of PEGylated SPIONs-Loaded Niosome for Codelivery of Paclitaxel and Trastuzumab for Breast Cancer Treatment: In Vivo Study

Masoumi, S., Asefnejad, A., & Bahrami, S. H. (2024) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c00027 · Cited by 13

Nanoparticles and Nanomaterials: A Review from the Standpoint of Pharmacy and Medicine

Petrov, G. V., Koldina, A. M., Ledenev, O. V., Tumasov, V. N., Nazarov, A. V., & Syroeshkin, A. V. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17050655 · Cited by 14

Super Para-Magnetic Iron Oxide Nanoparticles (SPIONs) in the Treatment of Cancer: Challenges, Approaches, and its Pivotal Role in Pancreatic, Colon, and Prostate Cancer

Khan, S. A., & Sharma, R. (2022) · Current Drug Delivery · doi:10.2174/1567201819666220509164611 · Cited by 13

Toxicological Aspects of Iron Oxide Nanoparticles

Fernández‐Bertólez, N., Costa, C., Brandão, F., Teixeira, J. P., Pásaro, E., Valdiglesias, V., & Laffón, B. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-88071-2_13 · Cited by 12

Energy Conversion and Biocompatibility of Surface Functionalized Magnetite Nanoparticles with Phosphonic Moieties

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Iron Oxide/Salicylic Acid Nanoparticles as Potential Therapy for B16F10 Melanoma Transplanted on the Chick Chorioallantoic Membrane

Predoi, M. C., Mîndrilă, I., Buteică, S. A., Purcaru, Ş. O., Mihăiescu, D. E., & Mărginean, O. M. (2020) · Processes · doi:10.3390/pr8060706 · Cited by 13

Magnetic triggers in biomedical applications – prospects for contact free cell sensing and guidance

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Nanomagnet-facilitated pharmaco-compatibility for cancer diagnostics: Underlying risks and the emergence of ultrasmall nanomagnets

Parimi, D. S., Gupta, Y., Marpu, S. B., Bhatt, C. S., Bollu, T. K., & Suresh, A. K. (2021) · Journal of Pharmaceutical Analysis · doi:10.1016/j.jpha.2021.11.002 · Cited by 13

MiRNA-520a-3p combined with folic acid conjugated Fe2O3@PDA multifunctional nanoagents for MR imagine and antitumor gene-photothermal therapy

Li, X., Wang, S., Gao, Q., Li, N., Dong, S., Gao, Y., Wang, Z., Zhang, B., & He, X. (2023) · Nanotechnology · doi:10.1088/1361-6528/acd5d9 · Cited by 11

Superparamagnetic nanoparticles as potential drug delivery systems for the treatment of Duchenne muscular dystrophy

Schumacher, M. L., Britos, T. N., Fonseca, F. L. A., Ferreira, F. F., Feder, D., Fratini, P., Petri, G., & Haddad, P. S. (2024) · Nanoscale · doi:10.1039/d4nr03407d · Cited by 11

A nontoxic biocompatible nanocomposite comprising black phosphorus with Au–γ-Fe 2 O 3 nanoparticles

Naskar, A., Kim, S., & Kim, K.-S. (2020) · RSC Advances · doi:10.1039/d0ra02476g · Cited by 11

A multiparametric model for the industrialization of co-precipitation synthesis of nano-commodities

Segovia, L. C. A., Agudelo, J. I. D., Glisoni, R. J., Acha, C., Zan, M. M. D., & Rintoul, I. (2020) · Nanotechnology · doi:10.1088/1361-6528/ab70d0 · Cited by 11

Simulation research on the forward problem of magnetoacoustic concentration tomography for magnetic nanoparticles with magnetic induction in a saturation magnetization state

Yan, X., Pan, Y., Chen, W., Xu, Z., & Li, Z. (2020) · Journal of Physics D Applied Physics · doi:10.1088/1361-6463/abc27c · Cited by 11

Phenotypic Switching of B16F10 Melanoma Cells as a Stress Adaptation Response to Fe3O4/Salicylic Acid Nanoparticle Therapy

Mîndrilă, I., Osman, A., Mîndrilă, B., Predoi, M. C., Mihăiescu, D. E., & Buteică, S. A. (2021) · Pharmaceuticals · doi:10.3390/ph14101007 · Cited by 11

Preparation and applications of calcium ferrite as a functional material: A review

Han, X., Duan, B., Liu, L., Fang, S., & Wang, W. (2024) · International Journal of Minerals Metallurgy and Materials · doi:10.1007/s12613-024-2966-9 · Cited by 10

Research on the Construction of Bispecific-Targeted Sustained-Release Drug-Delivery Microspheres and Their Function in Treatment of Hepatocellular Carcinoma

Huang, Z., Li, F., Zhang, J., Shi, X., Xu, Y., & Huang, X. (2022) · ACS Omega · doi:10.1021/acsomega.2c02584 · Cited by 10

Highly emissive hybrid mesoporous organometallo-silica nanoparticles for bioimaging

Ezquerro, C., López, I. P., Serrano, E., Alfaro‐Arnedo, E., Lalinde, E., Larráyoz, I. M., Pichel, J. G., García‐Martínez, J., & Berenguer, J. R. (2022) · Materials Advances · doi:10.1039/d1ma01243f · Cited by 10

Magnetite crystallization in a sodium-calcium-silicate glass with high iron oxide concentration–Effect on the magnetic properties

Harizanova, R., Mihailova, I., Georgieva, M., Tzankov, D., Cherkezova‐Zheleva, Z., Paneva, D. G., Avramova, I. A., Karashanova, D. B., Avdeev, G., Gugov, I., et al. (2024) · Journal of Non-Crystalline Solids · doi:10.1016/j.jnoncrysol.2024.122986 · Cited by 9

Cisplatin meets liposomes for a smarter delivery: A review

Stępień, M., Zajda, J., Keppler, B. K., Timerbaev, A. R., & Matczuk, M. (2025) · Talanta · doi:10.1016/j.talanta.2025.128331 · Cited by 9

Recent progress in cancer immunotherapy: Application of nano-therapeutic systems

Ghafelehbashi, R., Salehi, M., Kouhi, M., Naeini, A. A., Sajadi-Javan, Z. S., & Nejatidanesh, F. (2023) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2023.105184 · Cited by 9

In Vitro Magnetic Techniques for Investigating Cancer Progression

Libring, S., Enríquez, Á., Lee, H., & Solorio, L. (2021) · Cancers · doi:10.3390/cancers13174440 · Cited by 9

Non-Debye Behavior of the Néel and Brown Relaxation in Interacting Magnetic Nanoparticle Ensembles

Botez, C. E., & Knoop, J. (2024) · Materials · doi:10.3390/ma17163957 · Cited by 8

Stimuli-responsive polymer-coated iron oxide nanoparticles as drug delivery platforms

Ejderyan, N., Sanyal, R., & Sanyal, A. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824456-2.00009-6 · Cited by 8

Advancements in nanocarrier-mediated sunitinib delivery: Addressing obstacles and revealing its therapeutic promise in oncological treatment

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Heterogeneous Fenton-like activity of novel metallosalophen magnetic nanocomposites: significant anchoring group effect

Keikha, N., Rezaeifard, A., & Jafarpour, M. (2019) · RSC Advances · doi:10.1039/c9ra05097c · Cited by 8

Fundamentals of Superparamagnetic Iron Oxide Nanoparticles: Recent Update

Nehe, A., & Kulkarni, A. D. (2022) · Journal of Microscopy and Ultrastructure · doi:10.4103/jmau.jmau_17_22 · Cited by 8

Functional mixed metal oxide nanomaterials: a comprehensive review of their hyperthermic potential in cancer therapy

Pandhare, A. B., Mulik, S. V., Patil, S. S., Смотраєв, Р. В., Patil, R. S., & Delekar, S. D. (2025) · New Journal of Chemistry · doi:10.1039/d4nj02783c · Cited by 7

Porphyrin–iron oxide nanoparticle functionalized with trastuzumab (ION–PP–TZ) potential MR imaging probe for breast cancer cells

Eivazi, M., Khaniabadi, P. M., Hejazi, S. H., & Shahbazi‐Gahrouei, D. (2022) · Applied Physics A · doi:10.1007/s00339-022-05558-1 · Cited by 7

Superparamagnetic Iron Oxide Nanoparticle‐Based Drug Delivery in Cancer Therapeutics

Maity, D., Sudame, A., & Kandasamy, G. (2020) · doi:10.1002/9781119671732.ch7 · Cited by 7

Development and characterization of ciprofloxacin-loaded mesoporous silica-coated superparamagnetic iron oxide nanoparticles: Antioxidant, antimicrobial, and anticancer activity

Hessen, O. E. A., Darwish, M. M., & Mohamed, N. (2025) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2025.114589 · Cited by 6

Characterization of Mössbauer and Superparamagnetic Properties in Maghemite Nanoparticles Synthesized by a Sol–Gel Method

An, S. Y. (2023) · Journal of Electronic Materials · doi:10.1007/s11664-023-10569-6 · Cited by 6

Synthesis, characterization, and optimization of Co-, Mn-, and Zn-substituted ferrite nanoparticles and nanoclusters for cancer theranostic applications

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Development and in functional study of a bi-specific sustained release drug-loaded nano-liposomes for hepatocellular carcinoma

Zhang, Y.-F., Wu, X., Zhu, H., & Cong, Y. (2023) · Journal of Biomaterials Applications · doi:10.1177/08853282231179313 · Cited by 6

Functional polysaccharide-coated SPIONs for in vitro mRNA delivery in breast cancer cells

Tsave, O., Ψαρρού, Μ., Kastrinaki, G., Papachristou, E., Papi, R. M., Zaspalis, V. T., Nalbandian, L., Sarafidis, C., Ouranidis, A., Choli‐Papadopoulou, T., et al. (2024) · Materials Advances · doi:10.1039/d4ma00010b · Cited by 7

From Magnetic Moment to Magnetic Particle Imaging: A Comprehensive Review on MPI Technology, Tracer Design and Biological Applications

Negri, A., & Bongers, A. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18040497 · Cited by 5

Iron oxide nanoparticles: current and future applications in nanomedicine

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Magnetically guided Bi 2 S 3 @C/Fe 3 O 4 nanoparticles for enhanced photothermal-radiation synergy in glioblastoma treatment

Miao, B., Zhu, G., Lin, S., Zhang, C., Wang, Y., Chen, D., Liang, Y., & Wang, C. (2025) · RSC Advances · doi:10.1039/d5ra05381a · Cited by 4

Crafting Iron Oxides for Next-Generation Biomedical Applications

Amrillah, T., Notodidjojo, B. A., Kalimanjaro, M., Prastika, R. A., Nurrahman, A. M., Taufiq, A., Santoso, D., & Setyawan, D. (2024) · Crystal Growth & Design · doi:10.1021/acs.cgd.4c00015 · Cited by 6

Anxiety of microbially synthesized Fe3O4-SPIONs on embryonic/larval ontogeny in red tilapia (Oreochromis sp.)

Abouelkheir, S. S., & Mourad, M. M. (2025) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-024-13386-x · Cited by 5

Metal oxide-based composites for magnetic hyperthermia applications

Pandhare, A. B., Patil, R. S., & Delekar, S. D. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-85705-5.00019-1 · Cited by 4

Holothurian triterpene glycoside cucumarioside A2-2 induces macrophages activation and polarization in cancer immunotherapy

Chuang, W.-H., Pislyagin, Е. А., Lin, L., Menchinskaya, E. S., Chernikov, O. V., Kozhemyako, V. B., Gorpenchenko, T. Y., Manzhulo, I., Чайкина, Е. Л., Агафонова, И. Г., et al. (2023) · Cancer Cell International · doi:10.1186/s12935-023-03141-z · Cited by 4

Heparin-Modified Superparamagnetic Iron Oxide Nanoparticles Suppress Lithium Chloride/Pilocarpine-Induced Temporal Lobe Epilepsy in Rats through Attenuation of Inflammation and Oxidative Stress

Xu, H., Wang, Y., Yu, C., Han, C., & Cui, H. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.4c00188 · Cited by 4

Tailored Iron Oxide Nanoparticles as Potential Cannabinoid Carriers for Anti-Cancer Treatment

Taudul, J., Celej, J., Żelechowska-Matysiak, K., Kępińska, D., Majkowska‐Pilip, A., Strawski, M., Krysiński, P., & Nieciecka, D. (2025) · Biomolecules · doi:10.3390/biom15020230 · Cited by 4

Nanomedicine: future therapy for brain cancers

Haque, S., Norbert, C. C., & Patra, C. R. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819793-6.00003-5 · Cited by 4

New progress in tumor treatment based on nanoparticles combined with irreversible electroporation

Xu, L., Xie, L., Fang, C., Lou, W., & Jiang, T. (2022) · Nano Select · doi:10.1002/nano.202200064 · Cited by 4

High dielectric-energy storage and ferromagnetic-superparamagnetic properties: tetra-doping CuO nanocompositions

Youssef, A. M., & Yakout, S. M. (2023) · Journal of Materials Science Materials in Electronics · doi:10.1007/s10854-022-09564-0 · Cited by 4

Fabrication of gold–calcium phosphate composite nanoparticles through coprecipitation mediated by amino-terminated polyethylene glycol

Nakamura, M., Oyane, A., Kuroiwa, K., & Kosuge, H. (2020) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2020.111169 · Cited by 4

Construction of long-circulation EpCAM targeted drug delivery system and its application in the diagnosis and treatment of breast cancer

Song, C., Gao, C., Zhao, J., & Wang, Z. (2020) · Journal of Biomaterials Applications · doi:10.1177/0885328220965135 · Cited by 4

Inorganic Nanoparticles for Drug‐delivery Applications

Sabu, C., Shirin, V. K. A., Sankar, R., & Pramod, K. S. (2022) · doi:10.1002/9781119558026.ch14 · Cited by 4

Magnetically controlled drug-loaded coaxial electrospun suspension fibers for promoting Schwann cell myelination

Sun, S., Shang, Y., Wang, L., Jia, M., Shen, H., Han, Y., Gao, H., Liu, Y., Guan, W., Jin, N., et al. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.115098 · Cited by 3

Molecular Signal Reception in Complex Vessel Networks: The Role of the Network Topology

Jakumeit, T., Brand, L., Kirchner, J., Schober, R., & Lotter, S. (2025) · International Conference on Communications · doi:10.1109/icc52391.2025.11160711 · Cited by 3

Nickel-Oxide-Doped Borate Hench Glass for Magnetic Hyperthermia Applications

El-gendy, A., Salatein, N. M., Fahim, I. S., Abdelghany, A. M., Abdou, Y., ElHussiny, F. A., & Elmowafy, B. M. (2025) · Journal of Materials Engineering and Performance · doi:10.1007/s11665-025-12790-2 · Cited by 3

Magnetically separable Mangifera Indica leaf extract-mediated hematite nanoparticles potentiate cytotoxic activity

Sharma, A., Aggarwal, N., Panwar, R. S., Raja, V., Ali, D., Alarifi, S. A., Sharma, N., Radhakrishnan, A., & Kumar, N. (2024) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2024.140745 · Cited by 3

Nanozymatic activity assessment of iron oxide nanoparticle loaded chitosan-dextran sulfate matrix

Fahmy, H. M., Yassin, F. M., & Fathy, M. M. (2025) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2025.114237 · Cited by 3

The Cytotoxic Effect of Annona muricata-Loaded PHB-Coated Magnetic Nanoparticles on Cancer Cell Lines and Molecular Docking Analyses

Köksal, R., & Yalçın, S. (2020) · Current Pharmacology Reports · doi:10.1007/s40495-020-00220-x · Cited by 3

Inorganic Nanoparticles as Free Radical Scavengers

Fifere, A., Turin-Moleavin, I.-A., Lungoci, A.-L., Marangoci, N. L., & Pinteală, M. (2021) · Springer eBooks · doi:10.1007/978-3-030-57456-7_15 · Cited by 3

SPION based nanoformulations: bio-inspired design and functionalization strategies for applications in medicine

Tietze, R., & Alexiou, C. (2022) · Precision Nanomedicine · doi:10.33218/001c.35650 · Cited by 3

Polymeric and Inorganic Nanoparticles Targeting Chronic Respiratory Diseases

Chan, Y., Ng, S. W., & Soon, L. (2022) · Springer eBooks · doi:10.1007/978-981-16-4392-7_18 · Cited by 3

Evidence of Individual Superspin Relaxation in Diluted Fe3O4/Hexane Ferrofluids

Botez, C. E., & Musslewhite, Z. (2023) · Materials · doi:10.3390/ma16134850 · Cited by 3

Nanotheranostic Approach for the Management of Colorectal Cancer

Sharma, S., Kuppusamy, G., Chowdhury, P. R., & Pamu, D. (2023) · Nanoscience & Nanotechnology-Asia · doi:10.2174/2210681213666230823160616 · Cited by 3

P53 Pathway Activate Detection based on Machine Learning

Zhang, A., Liu, C., & Lin, G. (2021) · International Conference on Control Engineering and Artificial Intelligence (CCEAI) · doi:10.1145/3448218.3448237 · Cited by 3

A Combinatorial Approach for the Fabrication of Magneto-Optical Hybrid Nanoparticles

Koktysh, D. S., & Pham, W. N. (2019) · International Journal of Nanomedicine · doi:10.2147/ijn.s228962 · Cited by 3

Folic acid conjugation of magnetite nanoparticles using pulsed electrohydraulic discharges

Mikelashvili, V., Kekutia, S., Markhulia, J., Saneblidze, L., Jabua, Z., Almásy, L., & Kriechbaum, M. (2020) · Journal of the Serbian Chemical Society · doi:10.2298/jsc200414053m · Cited by 3

From fundamentals to applications: magnetic nanoparticles for MRI imaging and NIR-induced thermal activation in tissue-mimicking environments

Lapusan, R., Balmus, A., Fechete, R., Neamţu, B. V., Ponti, J., Borlan, R., & Focşan, M. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb01160d · Cited by 2

Magnetic hyperthermic and anticancer properties of hydrothermally synthesized magnetic nanoparticles using Gypsophila arrostii

Aksoy, H. R., Solak, K., Nadaroğlu, H., & Mavi, A. (2025) · Journal of Magnetism and Magnetic Materials · doi:10.1016/j.jmmm.2025.173639 · Cited by 2

Magnetic micro/nano robots for physical cell stimulation: fundamentals, fabrication, and applications

Chen, Y., Du, X., Law, J., & Sun, Y. (2025) · International Journal of Extreme Manufacturing · doi:10.1088/2631-7990/ae2242 · Cited by 2

Engineered Hybrid Nanoparticles for Multimodal Medical Imaging and Diagnosis

Shetty, A., & Chandra, S. (2022) · Springer eBooks · doi:10.1007/978-3-031-09636-5_12 · Cited by 2

Development of metal–polymer composite nanomaterials for diagnosis and phototherapy

Vydiam, K., Ahmad, J., & Mukherjee, S. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95758-8.00010-1 · Cited by 2

Design of Iron Oxide Nanoparticles as Theranostic Nanoplatforms for Cancer Treatment

Gevart, T., Freis, B., Vangijzegem, T., Ramírez, M. D. L. Á., Stanicki, D., Bégin‐Colin, S., & Laurent, S. (2024) · Topics in applied physics · doi:10.1007/978-3-031-58376-6_13 · Cited by 2

Corked Microcapsules Enabling Controlled Ultrasound-Mediated Protein Delivery

Singh, A., Dorogin, J., Baker, K., Que, J., Schimmer, P., Dowdall, N., Delfino, A., & Hoare, T. R. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c14615 · Cited by 2

Synthesis and Characterization of Magnetic Cellulose Powder from Sawdust Waste

Suryanto, H., Yanuhar, U., Wijaya, H. W., Binoj, J. S., Osman, A. F., Puspitasari, P., Maulana, J., Caesar, N. R., Nusantara, F., & Komarudin, K. (2024) · Journal of the Korean Wood Science and Technology · doi:10.5658/wood.2024.52.5.504 · Cited by 2

Effect of Early Enteral Nutrition of Three-Cavity Nasal Jejunal Tube Under Superparamagnetic Iron Oxide Nanoparticles (SPIONs) in Treatment of Severe Acute Pancreatitis

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