A pH-activated autocatalytic nanoreactor for self-boosting Fenton-like chemodynamic therapy
Abstract
A pH-activated autocatalytic nanoreactor was designed for self-boosted Fenton-like chemodynamic therapy via GSH depletion and H 2 O 2 self-sufficiency.
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CDT utilizes endogenous H2O2 in the TME to generate ·OH through Fenton or Fenton-like reactions catalyzed by nanomaterials containing transition metals.
“CDT utilizes endogenous H2O2 in the TME to generate ·OH through Fenton or Fenton-like reactions catalyzed by nanomaterials containing transition metals [122].”
From Nanosensitizer-assisted sonodynamic therapy for breast cancer (2025) · cites this paper as [122]
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Niu, B., Liao, K., Zhou, Y., Wen, T., Quan, G., Pan, X., & Wu, C. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121110 · Cited by 1,168 · see citing works
Nanosensitizer-assisted sonodynamic therapy for breast cancer
Yu, J., Hu, J.-R., Tian, Y., Lei, Y.-M., Hu, H.-M., Lei, B.-S., Zhang, G., Sun, Y., & Ye, H.-R. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03311-3 · Cited by 43 · see citing works
- Authors
- Wu, H., Chen, F., Gu, D., You, C., & Sun, B.
- Affiliations
- Southeast University (CN)
- Nanjing Forestry University (CN)
- School of Chemistry and Chemical Engineering
- Corresponding author
- You, Chaoqun
- Venue
- Nanoscale
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2020
- Volume
- 12
- Issue
- 33
- Pages
- 17319-17331
- ISSN
- 2040-3364 (ISSN-L)
- 2040-3372
- OpenAlex
- W3042539293
- Cited by
- 79
- References
- 0
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 10 · 2023: 17 · 2022: 19 · 2021: 17 · 2020: 2
- FWCI
- 4.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nanoscale (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (21905138, 21371031, 21628101)
- Natural Science Foundation of Jiangsu Province (BK20190756)
- China Postdoctoral Science Foundation (2019M651841)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Physical Sciences › Materials Science › Materials Chemistry › Advanced Nanomaterials in Catalysis
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- glutathione depletion, cancer nanomedicine, reactive oxygen species generation
- MeSH terms
- Glucose Oxidase, Glutathione, Hydrogen Peroxide, Hydrogen-Ion Concentration, Nanotechnology
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