Near-infrared (NIR) fluorescence-emitting small organic molecules for cancer imaging and therapy
Abstract
We discuss recent advances made in the development of NIR fluorescence-emitting small organic molecules for tumor imaging and therapy.
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These ROS induce apoptosis or necrosis in target cells, damage tumor vasculature, and may activate immune responses, collectively contributing to antitumor effects.
“These ROS induce apoptosis or necrosis in target cells, damage tumor vasculature, and may activate immune responses, collectively contributing to antitumor effects26.”
From Organic small-molecule NIR-II fluorophores for tumor phototheranostics (2026) · cites this paper as [26]
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References 254 · Cited by 356
- Authors
- Li, H., Kim, Y., Jung, H., Hyun, J. Y., & Shin, I.
- Affiliations
- Yonsei University (KR)
- Korea Research Institute of Chemical Technology (KR)
- Corresponding author
- Hyun, Ji Young
- Shin, Injae
- Venue
- Chemical Society Reviews
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2022
- Volume
- 51
- Issue
- 21
- Pages
- 8957-9008
- ISSN
- 0306-0012 (ISSN-L)
- 1460-4744
- OpenAlex
- W4306168162
- Cited by
- 356
- References
- 254
- Citations by year
- 2026: 68 · 2025: 111 · 2024: 114 · 2023: 60 · 2022: 3
- FWCI
- 6.42
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Chemical Society Reviews (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Korea Research Institute of Chemical Technology (BSF22-914, SI-2231-30)
- National Research Foundation of Korea (2020R1A2C3003462)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Nanoplatforms for cancer theranostics
- Physical Sciences › Materials Science › Materials Chemistry › Luminescence and Fluorescent Materials
- Physical Sciences › Chemistry › Spectroscopy › Molecular Sensors and Ion Detection
- Keywords
- near-infrared fluorophores, small organic molecules, tumor imaging, cancer therapy, photodynamic therapy, photothermal therapy, photoacoustic imaging, fluorescence imaging, tumor selectivity
- MeSH terms
- Diagnostic Imaging, Fluorescence, Fluorescent Dyes, Humans, Neoplasms, Optical Imaging
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