Optical 4D oxygen mapping of microperfused tissue models with tunable in vivo -like 3D oxygen microenvironments
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Abstract
Time-resolved optical 3D mapping of the oxygen distribution in 3D cell culture supports establishment and maintenance of in vivo like oxygen conditions.
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Former results using a single layer of perfusion channels showed full anoxia in the cultured cell volume within 10 min of stopping perfusion of medium.
“This is in agreement with our former results using a single layer of perfusion channels, where full anoxia in the cultured cell volume was observed within 10 min of stopping perfusion of medium [19] .”
From 3D microperfusion of mesoscale human microphysiological liver models improves functionality and recapitulates hepatic zonation (2023) · cites this paper as [19]
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Oxygenation in Cell Culture: Critical Parameters for Reproducibility Are Routinely Not Reported
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Cited by
Sorted by citations
Wesseler, M. F., Taebnia, N., Harrison, S., Youhanna, S., Preiss, L. C., Kemas, A. M., Vegvari, A., Mokry, J., Sullivan, G. J., Lauschke, V. M., et al. (2023) · Acta Biomaterialia · doi:10.1016/j.actbio.2023.09.022 · Cited by 39 · see citing works
Self-citation
- Authors
- Wesseler, M. F., Johansen, M. N., Kızıltay, A., Mortensen, K. I., & Larsen, N. B.
- Affiliations
- Department of Health Technology, DTU Health Tech, Technical University of Denmark, 2800 Kgs. Lyngby, Denmark
- Venue
- Lab on a Chip
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 2022
- Volume
- 22
- Issue
- 21
- Pages
- 4167-4179
- ISSN
- 1473-0197
- 1473-0189
- Cited by
- 18
- References
- 3
- Language
- en
- Funders
- Det Frie Forskningsråd (7017-00366B)
- Danmarks Tekniske Universitet
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
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