715. The synthesis of thyroxine and related substances. Part V. A synthesis of L-thyroxine from L-tyrosine

Chalmers, J. R.; Dickson, G. T.; Elks, J.; Hems, B. A.

doi:10.1039/jr9490003424

Cited by 67Thyroid Disorders and TreatmentsOxidative Organic Chemistry ReactionsOrganic Chemistry Synthesis Methods

715. The synthesis of thyroxine and related substances. Part V. A synthesis of L-thyroxine from L-tyrosine

Chalmers, J. R., Dickson, G. T., Elks, J., Hems, B. A.·1949·Journal of the Chemical Society (Resumed)

DOI 10.1039/jr9490003424

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J. R. Chalmers, G. T. Dickson, J. Elks and B. A. Hems, J. Chem. Soc., 1949, 3424 DOI: 10.1039/JR9490003424

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T4 and its better-absorbed sodium salt were synthesized by Chalmers et al.
“second, the synthesis of T4 (32) and its better-absorbed sodium salt by Chalmers et al. (33);”
From Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement (2014) · cites this paper as [33]

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Authors: Chalmers, J. R., Dickson, G. T., Elks, J., & Hems, B. A.
Venue: Journal of the Chemical Society (Resumed)
Publisher: Royal Society of Chemistry (RSC)
Published: 1949
Pages: 3424
ISSN: 0368-1769 (ISSN-L)
DOI: 10.1039/jr9490003424
OpenAlex: W2145894306
Cited by: 67
References: 0
Citations by year: 2025: 5 · 2024: 1 · 2022: 2 · 2021: 1 · 2020: 1 · 2019: 3 · 2016: 5 · 2015: 2 · 2014: 3 · 2013: 5
FWCI: 2.81
Type: journal article
Language: en
Open access: closed
Locations: Journal of the Chemical Society (Resumed) (publishedVersion)
Topics: Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
Physical Sciences › Chemistry › Organic Chemistry › Oxidative Organic Chemistry Reactions
Physical Sciences › Chemistry › Organic Chemistry › Organic Chemistry Synthesis Methods
Keywords: thyroxine, levothyroxine, tyrosine, total synthesis, thyroid hormones, amino acid derivatives

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715. The synthesis of thyroxine and related substances. Part V. A synthesis of L-thyroxine from L-tyrosine

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