Pulse radiolysis of sulphur compounds. Part 3.—Repair by hydrogen transfer of a macromolecule irradiated in aqueous solution
Abstract
Free radical repair by hydrogen transfer from a sulphydryl compound (cysteamine) has been extended to a polymeric system. Repair rate constants vary from 2.6 × 107 M–1 sec–1 for ethylene glycol to 5 × 106 M–1 sec–1 for polyethylene oxide (PEO) of molecular weight 20,000. The analysis of rate data for polymers of m.w. >200 is complicated by competing radical-radical reactions. A comprehensive reaction scheme is proposed and the kinetic equations solved numerically. The effects of pH and molecular weight on the repair rate have also been studied. Some further data on the pulse radiolysis of cysteamine solutions, including a determination of the extinction coefficient of the radical-ion RSSR–(ε4100= 9.4 ± 0.5 × 103 M–1 cm–1) are presented.
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The set of reactions resulting in formation of superoxide radicals is omnipresent and a critical component in biological systems.
“The above set of reactions, resulting in the formation of superoxide radicals, has been shown to be omnipresent and a critical component in biological systems (Poole 2015; Adams et al. 1969; Davies et al. 2022).”
From Reactive Oxygen Species, Toxicity, Oxidative Stress, and Antioxidants: Chronic Diseases and Aging (2023) · cites this paper as Adams et al. 1969
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- Authors
- Adams, G. E., Armstrong, R. C., Charlesby, A., Michael, B. D., & Willson, R. L.
- Venue
- Trans. Faraday Soc.
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 1969
- Volume
- 65
- Issue
- 0
- Pages
- 732-742
- ISSN
- 0014-7672 (ISSN-L)
- OpenAlex
- W1986816943
- Cited by
- 69
- References
- 0
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 7 · 2020: 2
- FWCI
- 6.32
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Transactions of the Faraday Society (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Organic Chemistry › Free Radicals and Antioxidants
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biophysics › Electron Spin Resonance Studies
- Physical Sciences › Chemistry › Physical and Theoretical Chemistry › Photochemistry and Electron Transfer Studies
- Keywords
- hydrogen transfer, cysteamine, thiols, poly(ethylene oxide), ethylene glycol, radiation chemistry of polymers, radical-radical reactions, reaction kinetics, pH effect, molecular weight effects
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