The DOI matches its OpenAlex record; 6 of the 6 references it cites were found in a registry or an index.
Carnitine biosynthesis in mammals
Open accessAbstract
Carnitine is indispensable for energy metabolism, since it enables activated fatty acids to enter the mitochondria, where they are broken down via beta-oxidation. Carnitine is probably present in all animal species, and in numerous micro-organisms and plants. In mammals, carnitine homoeostasis is maintained by endogenous synthesis, absorption from dietary sources and efficient tubular reabsorption by the kidney. This review aims to cover the current knowledge of the enzymological, molecular, metabolic and regulatory aspects of mammalian carnitine biosynthesis, with an emphasis on the human and rat.
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Citations
Cites
Carnitine—metabolism and functions
Bremer, J. (1983) · Physiological Reviews · doi:10.1152/physrev.1983.63.4.1420 · Cited by 1,666
The Mitochondrial Carnitine Palmitoyltransferase System — From Concept to Molecular Analysis
McGarry, J. D., & Brown, N. F. (1997) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1997.00001.x · Cited by 1,616
CARNITINE METABOLISM AND ITS REGULATION IN MICROORGANISMS AND MAMMALS
Rebouche, C. J., & Seim, H. (1998) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.18.1.39 · Cited by 362
Bacterial carnitine metabolism
Kleber, H.-P. (2006) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.1997.tb10212.x · Cited by 118
Rebouche, C. J. (1983) · The Journal of Nutrition · doi:10.1093/jn/113.10.1906 · Cited by 57
Marzo, A., & Curti, S. (1997) · Journal of Chromatography B Biomedical Sciences and Applications · doi:10.1016/s0378-4347(97)00376-9 · Cited by 29
Cited by
Oxygen sensing by HIF hydroxylases
Schofield, C. J., & Ratcliffe, P. J. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1366 · Cited by 2,068
Fe(II)/α-Ketoglutarate-Dependent Hydroxylases and Related Enzymes
Hausinger, R. P. (2004) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.1080/10409230490440541 · Cited by 937
Flanagan, J. L., Simmons, P. A., Vehige, J., Willcox, M. D., & Garrett, Q. (2010) · Nutrition & Metabolism · doi:10.1186/1743-7075-7-30 · Cited by 611
Schooneman, M. G., Vaz, F. M., Houten, S. M., & Soeters, M. R. (2013) · Diabetes · doi:10.2337/db12-0466 · Cited by 616
Self-citationNoland, R. C., Koves, T. R., Seiler, S. E., Lum, H., Lust, R. M., Ilkayeva, O., Stevens, R. D., Hegardt, F. G., & Muoio, D. M. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.032888 · Cited by 317
Metadata
- Authors
- Vaz, F. M., & Wanders, R. J. A.
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 2002-01-25
- Volume
- 361
- Issue
- 3
- Pages
- 417-429
- ISSN
- 0264-6021 (ISSN-L)
- 1470-8728
- OpenAlex
- W2067669340
- Cited by
- 764
- References
- 6
- FWCI
- 7.55
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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