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The frequency of errors in protein biosynthesis
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Every protein molecule consists basically of a
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“Error frequencies of 0.01-0.1% per amino acid (AA) have been estimated for misincorporating structurally similar amino acids in vivo 20 .”
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Metadata
- Authors
- Loftfield, R. B., & Vanderjagt, D.
- Affiliations
- University of New Mexico (US)
- Venue
- Biochemical Journal
- Publisher
- Portland Press Ltd.
- Published
- 1972-08-01
- Volume
- 128
- Issue
- 5
- Pages
- 1353-1356
- ISSN
- 0306-3283 (ISSN-L)
- PMC
- PMC1174024
- OpenAlex
- W1923250545
- Cited by
- 399
- References
- 3
- Citations by year
- 2026: 7 · 2025: 3 · 2024: 6 · 2023: 5 · 2022: 8 · 2021: 5 · 2020: 5 · 2019: 8 · 2018: 9 · 2017: 11 · 2016: 12 · 2015: 7 · 2014: 15 · 2013: 8 · 2012: 7
- FWCI
- 2.35
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Biochemical Journal (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › RNA and protein synthesis mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Protein Structure and Dynamics
- Keywords
- protein synthesis, error rate, translation errors, protein synthesis fidelity, aminoacyl-tRNA
- MeSH terms
- Amino Acid Sequence, Animals, DNA, Genetic Code, Hemoglobins, Hemoglobins, Abnormal, Humans, Rabbits, Reticulocytes, RNA, Transcription, Genetic, Protein Biosynthesis, In Vitro Techniques
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